Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CHI3L2 (chitinase 3 like 2)

Identity

Alias_nameschitinase 3-like 2
Alias_symbol (synonym)YKL-39
YKL39
Other aliasCHIL2
HGNC (Hugo) CHI3L2
LocusID (NCBI) 1117
Atlas_Id 52915
Location 1p13.2  [Link to chromosome band 1p13]
Location_base_pair Starts at 111227659 and ends at 111243440 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AQP1 (7p14.3) / CHI3L2 (1p13.3)MUCL1 (12q13.2) / CHI3L2 (1p13.3)AQP1 7p14.3 / CHI3L2 1p13.3
MUCL1 12q13.2 / CHI3L2 1p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CHI3L2   1933
Cards
Entrez_Gene (NCBI)CHI3L2  1117  chitinase 3 like 2
AliasesCHIL2; YKL-39; YKL39
GeneCards (Weizmann)CHI3L2
Ensembl hg19 (Hinxton)ENSG00000064886 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000064886 [Gene_View]  chr1:111227659-111243440 [Contig_View]  CHI3L2 [Vega]
ICGC DataPortalENSG00000064886
TCGA cBioPortalCHI3L2
AceView (NCBI)CHI3L2
Genatlas (Paris)CHI3L2
WikiGenes1117
SOURCE (Princeton)CHI3L2
Genetics Home Reference (NIH)CHI3L2
Genomic and cartography
GoldenPath hg38 (UCSC)CHI3L2  -     chr1:111227659-111243440 +  1p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHI3L2  -     1p13.2   [Description]    (hg19-Feb_2009)
EnsemblCHI3L2 - 1p13.2 [CytoView hg19]  CHI3L2 - 1p13.2 [CytoView hg38]
Mapping of homologs : NCBICHI3L2 [Mapview hg19]  CHI3L2 [Mapview hg38]
OMIM601526   
Gene and transcription
Genbank (Entrez)AK223316 AK298466 BC011460 BG698401 BM787868
RefSeq transcript (Entrez)NM_001025197 NM_001025199 NM_004000
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CHI3L2
Cluster EST : UnigeneHs.514840 [ NCBI ]
CGAP (NCI)Hs.514840
Alternative Splicing GalleryENSG00000064886
Gene ExpressionCHI3L2 [ NCBI-GEO ]   CHI3L2 [ EBI - ARRAY_EXPRESS ]   CHI3L2 [ SEEK ]   CHI3L2 [ MEM ]
Gene Expression Viewer (FireBrowse)CHI3L2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1117
GTEX Portal (Tissue expression)CHI3L2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15782   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15782  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15782
Splice isoforms : SwissVarQ15782
PhosPhoSitePlusQ15782
Domains : Interpro (EBI)CHI3L2    Chitinase_II    Chitinase_insertion    Glyco_hydro18_cat    Glyco_hydro_catalytic_dom    Glycoside_hydrolase_SF   
Domain families : Pfam (Sanger)Glyco_hydro_18 (PF00704)   
Domain families : Pfam (NCBI)pfam00704   
Domain families : Smart (EMBL)Glyco_18 (SM00636)  
Conserved Domain (NCBI)CHI3L2
DMDM Disease mutations1117
Blocks (Seattle)CHI3L2
PDB (SRS)4AY1    4P8U    4P8V    4P8W    4P8X   
PDB (PDBSum)4AY1    4P8U    4P8V    4P8W    4P8X   
PDB (IMB)4AY1    4P8U    4P8V    4P8W    4P8X   
PDB (RSDB)4AY1    4P8U    4P8V    4P8W    4P8X   
Structural Biology KnowledgeBase4AY1    4P8U    4P8V    4P8W    4P8X   
SCOP (Structural Classification of Proteins)4AY1    4P8U    4P8V    4P8W    4P8X   
CATH (Classification of proteins structures)4AY1    4P8U    4P8V    4P8W    4P8X   
SuperfamilyQ15782
Human Protein AtlasENSG00000064886
Peptide AtlasQ15782
HPRD03315
IPIIPI00019533   IPI00977027   IPI00978295   IPI00607646   IPI00979578   IPI00607669   IPI00984297   IPI00983614   IPI00977688   IPI00984767   IPI00980694   IPI00975844   
Protein Interaction databases
DIP (DOE-UCLA)Q15782
IntAct (EBI)Q15782
FunCoupENSG00000064886
BioGRIDCHI3L2
STRING (EMBL)CHI3L2
ZODIACCHI3L2
Ontologies - Pathways
QuickGOQ15782
Ontology : AmiGOchitinase activity  extracellular space  carbohydrate metabolic process  chitin binding  carbohydrate binding  
Ontology : EGO-EBIchitinase activity  extracellular space  carbohydrate metabolic process  chitin binding  carbohydrate binding  
NDEx NetworkCHI3L2
Atlas of Cancer Signalling NetworkCHI3L2
Wikipedia pathwaysCHI3L2
Orthology - Evolution
OrthoDB1117
GeneTree (enSembl)ENSG00000064886
Phylogenetic Trees/Animal Genes : TreeFamCHI3L2
HOVERGENQ15782
HOGENOMQ15782
Homologs : HomoloGeneCHI3L2
Homology/Alignments : Family Browser (UCSC)CHI3L2
Gene fusions - Rearrangements
Fusion : MitelmanAQP1/CHI3L2 [7p14.3/1p13.3]  [t(1;7)(p13;p14)]  
Fusion : MitelmanMUCL1/CHI3L2 [12q13.2/1p13.3]  [t(1;12)(p13;q13)]  
Fusion: TCGAAQP1 7p14.3 CHI3L2 1p13.3 LGG
Fusion: TCGAMUCL1 12q13.2 CHI3L2 1p13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHI3L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHI3L2
dbVarCHI3L2
ClinVarCHI3L2
1000_GenomesCHI3L2 
Exome Variant ServerCHI3L2
ExAC (Exome Aggregation Consortium)CHI3L2 (select the gene name)
Genetic variants : HAPMAP1117
Genomic Variants (DGV)CHI3L2 [DGVbeta]
DECIPHERCHI3L2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHI3L2 
Mutations
ICGC Data PortalCHI3L2 
TCGA Data PortalCHI3L2 
Broad Tumor PortalCHI3L2
OASIS PortalCHI3L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHI3L2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCHI3L2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CHI3L2
DgiDB (Drug Gene Interaction Database)CHI3L2
DoCM (Curated mutations)CHI3L2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHI3L2 (select a term)
intoGenCHI3L2
Cancer3DCHI3L2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601526   
Orphanet
MedgenCHI3L2
Genetic Testing Registry CHI3L2
NextProtQ15782 [Medical]
TSGene1117
GENETestsCHI3L2
Target ValidationCHI3L2
Huge Navigator CHI3L2 [HugePedia]
snp3D : Map Gene to Disease1117
BioCentury BCIQCHI3L2
ClinGenCHI3L2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1117
Chemical/Pharm GKB GenePA26464
Clinical trialCHI3L2
Miscellaneous
canSAR (ICR)CHI3L2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHI3L2
EVEXCHI3L2
GoPubMedCHI3L2
iHOPCHI3L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:02:17 CEST 2017

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