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CHIA (chitinase acidic)

Identity

Alias (NCBI)AMCASE
CHIT2
TSA1902
HGNC (Hugo) CHIA
HGNC Alias symbAMCase
TSA1902
CHIT2
HGNC Alias nameacidic mammalian chitinase
LocusID (NCBI) 27159
Atlas_Id 61796
Location 1p13.2  [Link to chromosome band 1p13]
Location_base_pair Starts at 111290851 and ends at 111320563 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
LRIG2 (1p13.2) / CHIA (1p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CHIA   17432
Cards
Entrez_Gene (NCBI)CHIA    chitinase acidic
AliasesAMCASE; CHIT2; TSA1902
GeneCards (Weizmann)CHIA
Ensembl hg19 (Hinxton)ENSG00000134216 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000134216 [Gene_View]  ENSG00000134216 [Sequence]  chr1:111290851-111320563 [Contig_View]  CHIA [Vega]
ICGC DataPortalENSG00000134216
TCGA cBioPortalCHIA
AceView (NCBI)CHIA
Genatlas (Paris)CHIA
SOURCE (Princeton)CHIA
Genetics Home Reference (NIH)CHIA
Genomic and cartography
GoldenPath hg38 (UCSC)CHIA  -     chr1:111290851-111320563 +  1p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHIA  -     1p13.2   [Description]    (hg19-Feb_2009)
GoldenPathCHIA - 1p13.2 [CytoView hg19]  CHIA - 1p13.2 [CytoView hg38]
ImmunoBaseENSG00000134216
Genome Data Viewer NCBICHIA [Mapview hg19]  
OMIM606080   
Gene and transcription
Genbank (Entrez)AB025008 AB025009 AF290004 AK098814 AK290702
RefSeq transcript (Entrez)NM_001040623 NM_001258001 NM_001258002 NM_001258003 NM_001258004 NM_001258005 NM_021797 NM_201653
Consensus coding sequences : CCDS (NCBI)CHIA
Gene ExpressionCHIA [ NCBI-GEO ]   CHIA [ EBI - ARRAY_EXPRESS ]   CHIA [ SEEK ]   CHIA [ MEM ]
Gene Expression Viewer (FireBrowse)CHIA [ Firebrowse - Broad ]
GenevisibleExpression of CHIA in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27159
GTEX Portal (Tissue expression)CHIA
Human Protein AtlasENSG00000134216-CHIA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZP6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZP6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZP6
Catalytic activity : Enzyme3.2.1.14 [ Enzyme-Expasy ]   3.2.1.143.2.1.14 [ IntEnz-EBI ]   3.2.1.14 [ BRENDA ]   3.2.1.14 [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9BZP6
Domaine pattern : Prosite (Expaxy)CHIT_BIND_II (PS50940)    GH18_1 (PS01095)    GH18_2 (PS51910)   
Domains : Interpro (EBI)Chitin-bd_dom    Chitin-bd_dom_sf    Chitinase_II    Chitinase_insertion_sf    Glyco_hydro18_cat    Glyco_hydro_18_chit_AS    Glycoside_hydrolase_SF   
Domain families : Pfam (Sanger)CBM_14 (PF01607)    Glyco_hydro_18 (PF00704)   
Domain families : Pfam (NCBI)pfam01607    pfam00704   
Domain families : Smart (EMBL)ChtBD2 (SM00494)  Glyco_18 (SM00636)  
Conserved Domain (NCBI)CHIA
PDB (RSDB)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
PDB Europe2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
PDB (PDBSum)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
PDB (IMB)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
Structural Biology KnowledgeBase2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
SCOP (Structural Classification of Proteins)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
CATH (Classification of proteins structures)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
SuperfamilyQ9BZP6
AlphaFold pdb e-kbQ9BZP6   
Human Protein Atlas [tissue]ENSG00000134216-CHIA [tissue]
HPRD09355
Protein Interaction databases
DIP (DOE-UCLA)Q9BZP6
IntAct (EBI)Q9BZP6
BioGRIDCHIA
STRING (EMBL)CHIA
ZODIACCHIA
Ontologies - Pathways
QuickGOQ9BZP6
Ontology : AmiGOpolysaccharide catabolic process  immune system process  production of molecular mediator involved in inflammatory response  chitinase activity  chitinase activity  chitinase activity  protein binding  extracellular region  extracellular region  extracellular space  cytoplasm  cytoplasm  chitin metabolic process  chitin catabolic process  chitin catabolic process  apoptotic process  chitin binding  kinase binding  positive regulation of chemokine production  polysaccharide digestion  
Ontology : EGO-EBIpolysaccharide catabolic process  immune system process  production of molecular mediator involved in inflammatory response  chitinase activity  chitinase activity  chitinase activity  protein binding  extracellular region  extracellular region  extracellular space  cytoplasm  cytoplasm  chitin metabolic process  chitin catabolic process  chitin catabolic process  apoptotic process  chitin binding  kinase binding  positive regulation of chemokine production  polysaccharide digestion  
Pathways : KEGGAminosugars metabolism   
NDEx NetworkCHIA
Atlas of Cancer Signalling NetworkCHIA
Wikipedia pathwaysCHIA
Orthology - Evolution
OrthoDB27159
GeneTree (enSembl)ENSG00000134216
Phylogenetic Trees/Animal Genes : TreeFamCHIA
Homologs : HomoloGeneCHIA
Homology/Alignments : Family Browser (UCSC)CHIA
Gene fusions - Rearrangements
Fusion : QuiverCHIA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHIA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHIA
dbVarCHIA
ClinVarCHIA
MonarchCHIA
1000_GenomesCHIA 
Exome Variant ServerCHIA
GNOMAD BrowserENSG00000134216
Varsome BrowserCHIA
ACMGCHIA variants
VarityQ9BZP6
Genomic Variants (DGV)CHIA [DGVbeta]
DECIPHERCHIA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHIA 
Mutations
ICGC Data PortalCHIA 
TCGA Data PortalCHIA 
Broad Tumor PortalCHIA
OASIS PortalCHIA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHIA  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCHIA
Mutations and Diseases : HGMDCHIA
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCHIA
DgiDB (Drug Gene Interaction Database)CHIA
DoCM (Curated mutations)CHIA
CIViC (Clinical Interpretations of Variants in Cancer)CHIA
Cancer3DCHIA
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606080   
Orphanet
DisGeNETCHIA
MedgenCHIA
Genetic Testing Registry CHIA
NextProtQ9BZP6 [Medical]
GENETestsCHIA
Target ValidationCHIA
Huge Navigator CHIA [HugePedia]
ClinGenCHIA
Clinical trials, drugs, therapy
MyCancerGenomeCHIA
Protein Interactions : CTDCHIA
Pharm GKB GenePA142672117
PharosQ9BZP6
Clinical trialCHIA
Miscellaneous
canSAR (ICR)CHIA
HarmonizomeCHIA
DataMed IndexCHIA
Probes
Litterature
PubMed43 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCHIA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:46:02 CEST 2021

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