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CHIA (chitinase, acidic)

Identity

Alias_symbol (synonym)AMCase
TSA1902
CHIT2
Other aliasAMCASE
HGNC (Hugo) CHIA
LocusID (NCBI) 27159
Atlas_Id 61796
Location 1p13.2  [Link to chromosome band 1p13]
Location_base_pair Starts at 111833474 and ends at 111863188 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
LRIG2 (1p13.2) / CHIA (1p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CHIA   17432
Cards
Entrez_Gene (NCBI)CHIA  27159  chitinase, acidic
AliasesAMCASE; CHIT2; TSA1902
GeneCards (Weizmann)CHIA
Ensembl hg19 (Hinxton)ENSG00000134216 [Gene_View]  chr1:111833474-111863188 [Contig_View]  CHIA [Vega]
Ensembl hg38 (Hinxton)ENSG00000134216 [Gene_View]  chr1:111833474-111863188 [Contig_View]  CHIA [Vega]
ICGC DataPortalENSG00000134216
TCGA cBioPortalCHIA
AceView (NCBI)CHIA
Genatlas (Paris)CHIA
WikiGenes27159
SOURCE (Princeton)CHIA
Genetics Home Reference (NIH)CHIA
Genomic and cartography
GoldenPath hg19 (UCSC)CHIA  -     chr1:111833474-111863188 +  1p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CHIA  -     1p13.2   [Description]    (hg38-Dec_2013)
EnsemblCHIA - 1p13.2 [CytoView hg19]  CHIA - 1p13.2 [CytoView hg38]
Mapping of homologs : NCBICHIA [Mapview hg19]  CHIA [Mapview hg38]
OMIM606080   
Gene and transcription
Genbank (Entrez)AB025008 AB025009 AF290004 AK098814 AK290702
RefSeq transcript (Entrez)NM_001040623 NM_001258001 NM_001258002 NM_001258003 NM_001258004 NM_001258005 NM_021797 NM_201653
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)CHIA
Cluster EST : UnigeneHs.128814 [ NCBI ]
CGAP (NCI)Hs.128814
Alternative Splicing GalleryENSG00000134216
Gene ExpressionCHIA [ NCBI-GEO ]   CHIA [ EBI - ARRAY_EXPRESS ]   CHIA [ SEEK ]   CHIA [ MEM ]
Gene Expression Viewer (FireBrowse)CHIA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27159
GTEX Portal (Tissue expression)CHIA
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZP6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZP6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZP6
Splice isoforms : SwissVarQ9BZP6
Catalytic activity : Enzyme3.2.1.14 [ Enzyme-Expasy ]   3.2.1.143.2.1.14 [ IntEnz-EBI ]   3.2.1.14 [ BRENDA ]   3.2.1.14 [ KEGG ]   
PhosPhoSitePlusQ9BZP6
Domaine pattern : Prosite (Expaxy)CHIT_BIND_II (PS50940)    CHITINASE_18 (PS01095)   
Domains : Interpro (EBI)Chitin-bd_dom    Chitinase_II    Chitinase_insertion    Glyco_hydro18cat    Glyco_hydro_18_chit_AS    Glyco_hydro_catalytic_dom    Glycoside_hydrolase_SF   
Domain families : Pfam (Sanger)CBM_14 (PF01607)    Glyco_hydro_18 (PF00704)   
Domain families : Pfam (NCBI)pfam01607    pfam00704   
Domain families : Smart (EMBL)ChtBD2 (SM00494)  Glyco_18 (SM00636)  
Conserved Domain (NCBI)CHIA
DMDM Disease mutations27159
Blocks (Seattle)CHIA
PDB (SRS)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
PDB (PDBSum)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
PDB (IMB)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
PDB (RSDB)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
Structural Biology KnowledgeBase2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
SCOP (Structural Classification of Proteins)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
CATH (Classification of proteins structures)2YBT    2YBU    3FXY    3FY1    3RM4    3RM8    3RM9    3RME   
SuperfamilyQ9BZP6
Human Protein AtlasENSG00000134216
Peptide AtlasQ9BZP6
HPRD09355
IPIIPI00033102   IPI00374037   IPI00374038   IPI00641931   IPI00973906   IPI00982930   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZP6
IntAct (EBI)Q9BZP6
FunCoupENSG00000134216
BioGRIDCHIA
STRING (EMBL)CHIA
ZODIACCHIA
Ontologies - Pathways
QuickGOQ9BZP6
Ontology : AmiGOpolysaccharide catabolic process  production of molecular mediator involved in inflammatory response  lysozyme activity  chitinase activity  chitinase activity  extracellular region  extracellular space  extracellular space  cytoplasm  cytoplasm  cytoplasm  chitin metabolic process  chitin catabolic process  chitin catabolic process  cell wall chitin metabolic process  apoptotic process  immune response  digestion  chitin binding  response to fungus  kinase binding  carbohydrate binding  positive regulation of chemokine secretion  
Ontology : EGO-EBIpolysaccharide catabolic process  production of molecular mediator involved in inflammatory response  lysozyme activity  chitinase activity  chitinase activity  extracellular region  extracellular space  extracellular space  cytoplasm  cytoplasm  cytoplasm  chitin metabolic process  chitin catabolic process  chitin catabolic process  cell wall chitin metabolic process  apoptotic process  immune response  digestion  chitin binding  response to fungus  kinase binding  carbohydrate binding  positive regulation of chemokine secretion  
Pathways : KEGGAmino sugar and nucleotide sugar metabolism   
NDEx NetworkCHIA
Atlas of Cancer Signalling NetworkCHIA
Wikipedia pathwaysCHIA
Orthology - Evolution
OrthoDB27159
GeneTree (enSembl)ENSG00000134216
Phylogenetic Trees/Animal Genes : TreeFamCHIA
HOVERGENQ9BZP6
HOGENOMQ9BZP6
Homologs : HomoloGeneCHIA
Homology/Alignments : Family Browser (UCSC)CHIA
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHIA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHIA
dbVarCHIA
ClinVarCHIA
1000_GenomesCHIA 
Exome Variant ServerCHIA
ExAC (Exome Aggregation Consortium)CHIA (select the gene name)
Genetic variants : HAPMAP27159
Genomic Variants (DGV)CHIA [DGVbeta]
DECIPHER (Syndromes)1:111833474-111863188  ENSG00000134216
CONAN: Copy Number AnalysisCHIA 
Mutations
ICGC Data PortalCHIA 
TCGA Data PortalCHIA 
Broad Tumor PortalCHIA
OASIS PortalCHIA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHIA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCHIA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CHIA
DgiDB (Drug Gene Interaction Database)CHIA
DoCM (Curated mutations)CHIA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHIA (select a term)
intoGenCHIA
Cancer3DCHIA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606080   
Orphanet
MedgenCHIA
Genetic Testing Registry CHIA
NextProtQ9BZP6 [Medical]
TSGene27159
GENETestsCHIA
Huge Navigator CHIA [HugePedia]
snp3D : Map Gene to Disease27159
BioCentury BCIQCHIA
ClinGenCHIA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27159
Chemical/Pharm GKB GenePA142672117
Clinical trialCHIA
Miscellaneous
canSAR (ICR)CHIA (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHIA
EVEXCHIA
GoPubMedCHIA
iHOPCHIA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:59:24 CET 2017

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