Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CHKB (choline kinase beta)

Identity

Other namesCHETK
CHKL
CK
CKB
CKEKB
EK
EKB
MDCMC
HGNC (Hugo) CHKB
LocusID (NCBI) 1120
Location 22q13.33
Location_base_pair Starts at 51017387 and ends at 51021428 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)CHKB   1938
Cards
Entrez_Gene (NCBI)CHKB  1120  choline kinase beta
GeneCards (Weizmann)CHKB
Ensembl (Hinxton)ENSG00000100288 [Gene_View]  chr22:51017387-51021428 [Contig_View]  CHKB [Vega]
ICGC DataPortalENSG00000100288
cBioPortalCHKB
AceView (NCBI)CHKB
Genatlas (Paris)CHKB
WikiGenes1120
SOURCE (Princeton)NM_005198 NM_152253
Genomic and cartography
GoldenPath (UCSC)CHKB  -  22q13.33   chr22:51017387-51021428 -  22q13.33   [Description]    (hg19-Feb_2009)
EnsemblCHKB - 22q13.33 [CytoView]
Mapping of homologs : NCBICHKB [Mapview]
OMIM602541   612395   
Gene and transcription
Genbank (Entrez)AB029886 AK097775 AK314324 AL096780 AL096781
RefSeq transcript (Entrez)NM_005198 NM_152253
RefSeq genomic (Entrez)AC_000154 NC_000022 NC_018933 NG_012643 NG_029213 NT_011526 NW_001838756 NW_004929431
Consensus coding sequences : CCDS (NCBI)CHKB
Cluster EST : UnigeneHs.654827 [ NCBI ]
CGAP (NCI)Hs.654827
Alternative Splicing : Fast-db (Paris)GSHG0020525
Alternative Splicing GalleryENSG00000100288
Gene ExpressionCHKB [ NCBI-GEO ]     CHKB [ SEEK ]   CHKB [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y259 (Uniprot)
NextProtQ9Y259  [Medical]
With graphics : InterProQ9Y259
Splice isoforms : SwissVarQ9Y259 (Swissvar)
Catalytic activity : Enzyme2.7.1.32 [ Enzyme-Expasy ]   2.7.1.322.7.1.32 [ IntEnz-EBI ]   2.7.1.32 [ BRENDA ]   2.7.1.32 [ KEGG ]   
Domains : Interpro (EBI)Kinase-like_dom [organisation]  
Related proteins : CluSTrQ9Y259
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations1120
Blocks (Seattle)Q9Y259
PDB (SRS)2IG7    3FEG    3LQ3   
PDB (PDBSum)2IG7    3FEG    3LQ3   
PDB (IMB)2IG7    3FEG    3LQ3   
PDB (RSDB)2IG7    3FEG    3LQ3   
Human Protein AtlasENSG00000100288 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9Y259
HPRD07631
IPIIPI00031758   IPI00376947   IPI00815846   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y259
IntAct (EBI)Q9Y259
FunCoupENSG00000100288
BioGRIDCHKB
InParanoidQ9Y259
Interologous Interaction database Q9Y259
IntegromeDBCHKB
STRING (EMBL)CHKB
Ontologies - Pathways
Ontology : AmiGOcholine kinase activity  ethanolamine kinase activity  ATP binding  cytoplasm  cytosol  phospholipid metabolic process  phosphatidylethanolamine biosynthetic process  phosphatidylethanolamine biosynthetic process  phosphatidylethanolamine biosynthetic process  phosphatidylcholine biosynthetic process  CDP-choline pathway  small molecule metabolic process  glycerophospholipid biosynthetic process  
Ontology : EGO-EBIcholine kinase activity  ethanolamine kinase activity  ATP binding  cytoplasm  cytosol  phospholipid metabolic process  phosphatidylethanolamine biosynthetic process  phosphatidylethanolamine biosynthetic process  phosphatidylethanolamine biosynthetic process  phosphatidylcholine biosynthetic process  CDP-choline pathway  small molecule metabolic process  glycerophospholipid biosynthetic process  
Pathways : KEGGGlycerophospholipid metabolism   
Protein Interaction DatabaseCHKB
Wikipedia pathwaysCHKB
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CHKB
snp3D : Map Gene to Disease1120
SNP (GeneSNP Utah)CHKB
SNP : HGBaseCHKB
Genetic variants : HAPMAPCHKB
Exome VariantCHKB
1000_GenomesCHKB 
ICGC programENSG00000100288 
Somatic Mutations in Cancer : COSMICCHKB 
CONAN: Copy Number AnalysisCHKB 
Mutations and Diseases : HGMDCHKB
Genomic VariantsCHKB  CHKB [DGVbeta]
dbVarCHKB
ClinVarCHKB
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM602541    612395   
MedgenCHKB
GENETestsCHKB
Disease Genetic AssociationCHKB
Huge Navigator CHKB [HugePedia]  CHKB [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneCHKB
Homology/Alignments : Family Browser (UCSC)CHKB
Phylogenetic Trees/Animal Genes : TreeFamCHKB
Chemical/Protein Interactions : CTD1120
Chemical/Pharm GKB GenePA26469
Clinical trialCHKB
Cancer Resource (Charite)ENSG00000100288
Other databases
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
CoreMineCHKB
iHOPCHKB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 16:49:47 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.