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CHKB (choline kinase beta)

Identity

Other namesCHETK
CHKL
CK
CKB
CKEKB
EK
EKB
MDCMC
HGNC (Hugo) CHKB
LocusID (NCBI) 1120
Atlas_Id 51457
Location 22q13.33
Location_base_pair Starts at 51017387 and ends at 51021428 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CHKB   1938
Cards
Entrez_Gene (NCBI)CHKB  1120  choline kinase beta
AliasesCHETK; CHKL; CK; CKB; 
CKEKB; EK; EKB; MDCMC
GeneCards (Weizmann)CHKB
Ensembl hg19 (Hinxton)ENSG00000100288 [Gene_View]  chr22:51017387-51021428 [Contig_View]  CHKB [Vega]
Ensembl hg38 (Hinxton)ENSG00000100288 [Gene_View]  chr22:51017387-51021428 [Contig_View]  CHKB [Vega]
ICGC DataPortalENSG00000100288
TCGA cBioPortalCHKB
AceView (NCBI)CHKB
Genatlas (Paris)CHKB
WikiGenes1120
SOURCE (Princeton)CHKB
Genomic and cartography
GoldenPath hg19 (UCSC)CHKB  -     chr22:51017387-51021428 -  22q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CHKB  -     22q13.33   [Description]    (hg38-Dec_2013)
EnsemblCHKB - 22q13.33 [CytoView hg19]  CHKB - 22q13.33 [CytoView hg38]
Mapping of homologs : NCBICHKB [Mapview hg19]  CHKB [Mapview hg38]
OMIM602541   612395   
Gene and transcription
Genbank (Entrez)AB029886 AK097775 AK314324 AL096780 AL096781
RefSeq transcript (Entrez)NM_005198 NM_152253
RefSeq genomic (Entrez)NC_000022 NC_018933 NG_012643 NG_029213 NT_011526 NW_004929431
Consensus coding sequences : CCDS (NCBI)CHKB
Cluster EST : UnigeneHs.654827 [ NCBI ]
CGAP (NCI)Hs.654827
Alternative Splicing GalleryENSG00000100288
Gene ExpressionCHKB [ NCBI-GEO ]   CHKB [ EBI - ARRAY_EXPRESS ]   CHKB [ SEEK ]   CHKB [ MEM ]
Gene Expression Viewer (FireBrowse)CHKB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1120
GTEX Portal (Tissue expression)CHKB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y259 (Uniprot)
NextProtQ9Y259  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y259
Splice isoforms : SwissVarQ9Y259 (Swissvar)
Catalytic activity : Enzyme2.7.1.32 [ Enzyme-Expasy ]   2.7.1.322.7.1.32 [ IntEnz-EBI ]   2.7.1.32 [ BRENDA ]   2.7.1.32 [ KEGG ]   
PhosPhoSitePlusQ9Y259
Domains : Interpro (EBI)Cho/Etha_kinase    Kinase-like_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations1120
Blocks (Seattle)CHKB
PDB (SRS)2IG7    3FEG    3LQ3   
PDB (PDBSum)2IG7    3FEG    3LQ3   
PDB (IMB)2IG7    3FEG    3LQ3   
PDB (RSDB)2IG7    3FEG    3LQ3   
Structural Biology KnowledgeBase2IG7    3FEG    3LQ3   
SCOP (Structural Classification of Proteins)2IG7    3FEG    3LQ3   
CATH (Classification of proteins structures)2IG7    3FEG    3LQ3   
SuperfamilyQ9Y259
Human Protein AtlasENSG00000100288
Peptide AtlasQ9Y259
HPRD07631
IPIIPI00031758   IPI00376947   IPI00815846   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y259
IntAct (EBI)Q9Y259
FunCoupENSG00000100288
BioGRIDCHKB
STRING (EMBL)CHKB
ZODIACCHKB
Ontologies - Pathways
QuickGOQ9Y259
Ontology : AmiGOcholine kinase activity  choline kinase activity  ethanolamine kinase activity  ethanolamine kinase activity  ATP binding  cytosol  phosphatidylethanolamine biosynthetic process  phosphatidylethanolamine biosynthetic process  phosphatidylethanolamine biosynthetic process  phosphatidylcholine biosynthetic process  CDP-choline pathway  CDP-choline pathway  CDP-choline pathway  phosphorylation  
Ontology : EGO-EBIcholine kinase activity  choline kinase activity  ethanolamine kinase activity  ethanolamine kinase activity  ATP binding  cytosol  phosphatidylethanolamine biosynthetic process  phosphatidylethanolamine biosynthetic process  phosphatidylethanolamine biosynthetic process  phosphatidylcholine biosynthetic process  CDP-choline pathway  CDP-choline pathway  CDP-choline pathway  phosphorylation  
Pathways : KEGGGlycerophospholipid metabolism   
NDEx Network
Atlas of Cancer Signalling NetworkCHKB
Wikipedia pathwaysCHKB
Orthology - Evolution
OrthoDB1120
GeneTree (enSembl)ENSG00000100288
Phylogenetic Trees/Animal Genes : TreeFamCHKB
Homologs : HomoloGeneCHKB
Homology/Alignments : Family Browser (UCSC)CHKB
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCHKB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHKB
dbVarCHKB
ClinVarCHKB
1000_GenomesCHKB 
Exome Variant ServerCHKB
ExAC (Exome Aggregation Consortium)CHKB (select the gene name)
Genetic variants : HAPMAP1120
Genomic Variants (DGV)CHKB [DGVbeta]
Mutations
ICGC Data PortalCHKB 
TCGA Data PortalCHKB 
Broad Tumor PortalCHKB
OASIS PortalCHKB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHKB 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)Leiden Muscular Dystrophy pages
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch CHKB
DgiDB (Drug Gene Interaction Database)CHKB
DoCM (Curated mutations)CHKB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHKB (select a term)
intoGenCHKB
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)22:51017387-51021428  ENSG00000100288
CONAN: Copy Number AnalysisCHKB 
Mutations and Diseases : HGMDCHKB
OMIM602541    612395   
MedgenCHKB
Genetic Testing Registry CHKB
NextProtQ9Y259 [Medical]
TSGene1120
GENETestsCHKB
Huge Navigator CHKB [HugePedia]
snp3D : Map Gene to Disease1120
BioCentury BCIQCHKB
ClinGenCHKB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1120
Chemical/Pharm GKB GenePA26469
Clinical trialCHKB
Miscellaneous
canSAR (ICR)CHKB (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHKB
EVEXCHKB
GoPubMedCHKB
iHOPCHKB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 10:57:46 CEST 2016

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