Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CHMP4C (charged multivesicular body protein 4C)

Identity

Alias_nameschromatin modifying protein 4C
Alias_symbol (synonym)MGC22825
Shax3
VPS32C
Other aliasSNF7-3
HGNC (Hugo) CHMP4C
LocusID (NCBI) 92421
Atlas_Id 53354
Location 8q21.13  [Link to chromosome band 8q21]
Location_base_pair Starts at 81732453 and ends at 81759513 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CHMP4C   30599
Cards
Entrez_Gene (NCBI)CHMP4C  92421  charged multivesicular body protein 4C
AliasesSNF7-3; Shax3; VPS32C
GeneCards (Weizmann)CHMP4C
Ensembl hg19 (Hinxton)ENSG00000164695 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000164695 [Gene_View]  chr8:81732453-81759513 [Contig_View]  CHMP4C [Vega]
ICGC DataPortalENSG00000164695
TCGA cBioPortalCHMP4C
AceView (NCBI)CHMP4C
Genatlas (Paris)CHMP4C
WikiGenes92421
SOURCE (Princeton)CHMP4C
Genetics Home Reference (NIH)CHMP4C
Genomic and cartography
GoldenPath hg38 (UCSC)CHMP4C  -     chr8:81732453-81759513 +  8q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHMP4C  -     8q21.13   [Description]    (hg19-Feb_2009)
EnsemblCHMP4C - 8q21.13 [CytoView hg19]  CHMP4C - 8q21.13 [CytoView hg38]
Mapping of homologs : NCBICHMP4C [Mapview hg19]  CHMP4C [Mapview hg38]
OMIM610899   
Gene and transcription
Genbank (Entrez)AB120734 AK000049 AK314873 AY329086 BC014321
RefSeq transcript (Entrez)NM_152284
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CHMP4C
Cluster EST : UnigeneHs.183861 [ NCBI ]
CGAP (NCI)Hs.183861
Alternative Splicing GalleryENSG00000164695
Gene ExpressionCHMP4C [ NCBI-GEO ]   CHMP4C [ EBI - ARRAY_EXPRESS ]   CHMP4C [ SEEK ]   CHMP4C [ MEM ]
Gene Expression Viewer (FireBrowse)CHMP4C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)92421
GTEX Portal (Tissue expression)CHMP4C
Human Protein AtlasENSG00000164695-CHMP4C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96CF2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96CF2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96CF2
Splice isoforms : SwissVarQ96CF2
PhosPhoSitePlusQ96CF2
Domains : Interpro (EBI)Snf7_fam   
Domain families : Pfam (Sanger)Snf7 (PF03357)   
Domain families : Pfam (NCBI)pfam03357   
Conserved Domain (NCBI)CHMP4C
DMDM Disease mutations92421
Blocks (Seattle)CHMP4C
PDB (SRS)3C3R   
PDB (PDBSum)3C3R   
PDB (IMB)3C3R   
PDB (RSDB)3C3R   
Structural Biology KnowledgeBase3C3R   
SCOP (Structural Classification of Proteins)3C3R   
CATH (Classification of proteins structures)3C3R   
SuperfamilyQ96CF2
Human Protein Atlas [tissue]ENSG00000164695-CHMP4C [tissue]
Peptide AtlasQ96CF2
HPRD18135
IPIIPI00060414   
Protein Interaction databases
DIP (DOE-UCLA)Q96CF2
IntAct (EBI)Q96CF2
FunCoupENSG00000164695
BioGRIDCHMP4C
STRING (EMBL)CHMP4C
ZODIACCHMP4C
Ontologies - Pathways
QuickGOQ96CF2
Ontology : AmiGOESCRT III complex  cell separation after cytokinesis  protein binding  cytosol  nucleus organization  vacuolar transport  mitotic metaphase plate congression  abscission  regulation of centrosome duplication  protein transport  endosomal transport  macroautophagy  viral life cycle  midbody  late endosome membrane  negative regulation of cytokinesis  multivesicular body assembly  viral budding via host ESCRT complex  protein homodimerization activity  regulation of viral process  extracellular exosome  Flemming body  ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway  regulation of mitotic spindle assembly  positive regulation of viral release from host cell  
Ontology : EGO-EBIESCRT III complex  cell separation after cytokinesis  protein binding  cytosol  nucleus organization  vacuolar transport  mitotic metaphase plate congression  abscission  regulation of centrosome duplication  protein transport  endosomal transport  macroautophagy  viral life cycle  midbody  late endosome membrane  negative regulation of cytokinesis  multivesicular body assembly  viral budding via host ESCRT complex  protein homodimerization activity  regulation of viral process  extracellular exosome  Flemming body  ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway  regulation of mitotic spindle assembly  positive regulation of viral release from host cell  
Pathways : KEGGEndocytosis   
NDEx NetworkCHMP4C
Atlas of Cancer Signalling NetworkCHMP4C
Wikipedia pathwaysCHMP4C
Orthology - Evolution
OrthoDB92421
GeneTree (enSembl)ENSG00000164695
Phylogenetic Trees/Animal Genes : TreeFamCHMP4C
HOVERGENQ96CF2
HOGENOMQ96CF2
Homologs : HomoloGeneCHMP4C
Homology/Alignments : Family Browser (UCSC)CHMP4C
Gene fusions - Rearrangements
Tumor Fusion PortalCHMP4C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHMP4C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHMP4C
dbVarCHMP4C
ClinVarCHMP4C
1000_GenomesCHMP4C 
Exome Variant ServerCHMP4C
ExAC (Exome Aggregation Consortium)ENSG00000164695
GNOMAD BrowserENSG00000164695
Genetic variants : HAPMAP92421
Genomic Variants (DGV)CHMP4C [DGVbeta]
DECIPHERCHMP4C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHMP4C 
Mutations
ICGC Data PortalCHMP4C 
TCGA Data PortalCHMP4C 
Broad Tumor PortalCHMP4C
OASIS PortalCHMP4C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHMP4C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCHMP4C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CHMP4C
DgiDB (Drug Gene Interaction Database)CHMP4C
DoCM (Curated mutations)CHMP4C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHMP4C (select a term)
intoGenCHMP4C
Cancer3DCHMP4C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610899   
Orphanet
DisGeNETCHMP4C
MedgenCHMP4C
Genetic Testing Registry CHMP4C
NextProtQ96CF2 [Medical]
TSGene92421
GENETestsCHMP4C
Target ValidationCHMP4C
Huge Navigator CHMP4C [HugePedia]
snp3D : Map Gene to Disease92421
BioCentury BCIQCHMP4C
ClinGenCHMP4C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD92421
Chemical/Pharm GKB GenePA142672113
Clinical trialCHMP4C
Miscellaneous
canSAR (ICR)CHMP4C (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHMP4C
EVEXCHMP4C
GoPubMedCHMP4C
iHOPCHMP4C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:07:41 CET 2017

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