CHN2 (chimerin (chimaerin) 2)

Identity

Other names	ARHGAP3
	BCH
	MGC138360
	RHOGAP3
HGNC	CHN2
Location	7p15.3
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	CHN2   1944
Entrez_Gene	CHN2  1124  chimerin (chimaerin) 2
	Cards
GeneCards	CHN2
Ensembl	CHN2 [Search_View]   ENSG00000106069 [Gene_View]
Genatlas	CHN2
GeneLynx	CHN2
eGenome	CHN2
euGene	1124
	Genomic and cartography
GoldenPath	CHN2  -  7p15.3   chr7:29486011-29520469 +  7p15.1   [Description]    (hg18-March_2006)
Ensembl	CHN2 - 7p15.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	CHN2
	Gene and transcription
Genbank	AA521339 [ ENTREZ ]
Genbank	AF147327 [ ENTREZ ]
Genbank	AK026415 [ ENTREZ ]
Genbank	AK123927 [ ENTREZ ]
Genbank	AK124021 [ ENTREZ ]
RefSeq	NM_001039936 [ SRS ]    NM_001039936 [ ENTREZ ]
RefSeq	NM_004067 [ SRS ]    NM_004067 [ ENTREZ ]
RefSeq	AC_000050 [ SRS ]    AC_000050 [ ENTREZ ]
RefSeq	AC_000068 [ SRS ]    AC_000068 [ ENTREZ ]
RefSeq	AC_000139 [ SRS ]    AC_000139 [ ENTREZ ]
RefSeq	NC_000007 [ SRS ]    NC_000007 [ ENTREZ ]
RefSeq	NT_007819 [ SRS ]    NT_007819 [ ENTREZ ]
RefSeq	NT_079592 [ SRS ]    NT_079592 [ ENTREZ ]
RefSeq	NW_001839003 [ SRS ]    NW_001839003 [ ENTREZ ]
RefSeq	NW_923240 [ SRS ]    NW_923240 [ ENTREZ ]
AceView	CHN2 AceView - NCBI
Unigene	Hs.710429 [ SRS ]    Hs.710429 [ NCBI ]     HS710429 [ spliceNest ]
Fast-db	3366 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P52757 [ SRS]    P52757 [ EXPASY ]     P52757 [ INTERPRO ]     P52757 [ UNIPROT ]
Prosite	PS50238 RHOGAP [ SRS ]    PS50238 RHOGAP [ Expasy ]
Prosite	PS50001 SH2 [ SRS ]    PS50001 SH2 [ Expasy ]
Prosite	PS00479 ZF_DAG_PE_1 [ SRS ]    PS00479 ZF_DAG_PE_1 [ Expasy ]
Prosite	PS50081 ZF_DAG_PE_2 [ SRS ]    PS50081 ZF_DAG_PE_2 [ Expasy ]
Interpro	IPR002219 DAG_PE_bd [ SRS ]    IPR002219 DAG_PE_bd [ EBI ]
Interpro	IPR017356 N-chimaerin [ SRS ]    IPR017356 N-chimaerin [ EBI ]
Interpro	IPR000198 RhoGAP [ SRS ]    IPR000198 RhoGAP [ EBI ]
Interpro	IPR000980 SH2 [ SRS ]    IPR000980 SH2 [ EBI ]
CluSTr	P52757
Pfam	PF00130 C1_1 [ SRS ]    PF00130 C1_1 [ Sanger ]    pfam00130 [ NCBI-CDD ]
Pfam	PF00620 RhoGAP [ SRS ]    PF00620 RhoGAP [ Sanger ]    pfam00620 [ NCBI-CDD ]
Pfam	PF00017 SH2 [ SRS ]    PF00017 SH2 [ Sanger ]    pfam00017 [ NCBI-CDD ]
Smart	SM00109 C1 [EMBL]
Smart	SM00324 RhoGAP [EMBL]
Smart	SM00252 SH2 [EMBL]
Prodom	PD000093 SH2[INRA-Toulouse]
Prodom	P52757 CHIO_HUMAN [ Domain structure ]   P52757 CHIO_HUMAN  [ sequences sharing at least 1 domain ]
Blocks	P52757
PDB	1XA6 [ SRS ]    1XA6 [ PdbSum ],   1XA6 [ IMB ]   1XA6 [ RSDB ]
HPRD	04173
	Protein Interaction databases
DIP	P52757
IntAct	P52757
	Polymorphism : SNP, mutations, diseases
OMIM	602857    [ map ]
GENECLINICS	602857
SNP	CHN2 [dbSNP-NCBI]
SNP	NM_001039936 [SNP-NCI]
SNP	NM_004067 [SNP-NCI]
SNP	CHN2 [GeneSNPs - Utah]  CHN2] [HGBASE - SRS]
HAPMAP	CHN2 [HAPMAP]
COSMIC	CHN2 [Somatic mutation (COSMIC-CGP-Sanger)]
HGMD	CHN2
	General knowledge
Family Browser	CHN2 [UCSC Family Browser]
SOURCE	NM_001039936
SOURCE	NM_004067
SMD	Hs.710429
SAGE	Hs.710429
GO	SH3/SH2 adaptor activity [Amigo]  SH3/SH2 adaptor activity
GO	GTPase activator activity [Amigo]  GTPase activator activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	zinc ion binding [Amigo]  zinc ion binding
GO	membrane [Amigo]  membrane
GO	diacylglycerol binding [Amigo]  diacylglycerol binding
GO	metal ion binding [Amigo]  metal ion binding
PubGene	CHN2
TreeFam	CHN2
CTD	1124 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	CHN2 Related clones (RZPD - Berlin)
	PubMed
PubMed	26 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Sep 29 17:52:40 2008