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CHP1 (calcineurin like EF-hand protein 1)

Identity

Alias (NCBI)CHP
SLC9A1BP
SPAX9
Sid470p
p22
p24
HGNC (Hugo) CHP1
HGNC Alias symbSid470p
CHP
SLC9A1BP
p22
p24
HGNC Alias namecalcineurin homologous protein
LocusID (NCBI) 11261
Atlas_Id 50667
Location 15q15.1  [Link to chromosome band 15q15]
Location_base_pair Starts at 41231268 and ends at 41281885 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CHP1   17433
Cards
Entrez_Gene (NCBI)CHP1    calcineurin like EF-hand protein 1
AliasesCHP; SLC9A1BP; SPAX9; Sid470p; 
p22; p24
GeneCards (Weizmann)CHP1
Ensembl hg19 (Hinxton)ENSG00000187446 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187446 [Gene_View]  ENSG00000187446 [Sequence]  chr15:41231268-41281885 [Contig_View]  CHP1 [Vega]
ICGC DataPortalENSG00000187446
TCGA cBioPortalCHP1
AceView (NCBI)CHP1
Genatlas (Paris)CHP1
SOURCE (Princeton)CHP1
Genetics Home Reference (NIH)CHP1
Genomic and cartography
GoldenPath hg38 (UCSC)CHP1  -     chr15:41231268-41281885 +  15q15.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHP1  -     15q15.1   [Description]    (hg19-Feb_2009)
GoldenPathCHP1 - 15q15.1 [CytoView hg19]  CHP1 - 15q15.1 [CytoView hg38]
ImmunoBaseENSG00000187446
Genome Data Viewer NCBICHP1 [Mapview hg19]  
OMIM606988   618438   
Gene and transcription
Genbank (Entrez)AK000095 AK094363 AK299660 AK307060 AK312582
RefSeq transcript (Entrez)NM_007236
Consensus coding sequences : CCDS (NCBI)CHP1
Gene ExpressionCHP1 [ NCBI-GEO ]   CHP1 [ EBI - ARRAY_EXPRESS ]   CHP1 [ SEEK ]   CHP1 [ MEM ]
Gene Expression Viewer (FireBrowse)CHP1 [ Firebrowse - Broad ]
GenevisibleExpression of CHP1 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11261
GTEX Portal (Tissue expression)CHP1
Human Protein AtlasENSG00000187446-CHP1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99653   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99653  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99653
PhosPhoSitePlusQ99653
Domaine pattern : Prosite (Expaxy)EF_HAND_2 (PS50222)   
Domains : Interpro (EBI)EF-hand-dom_pair    EF_hand_dom   
Domain families : Pfam (Sanger)EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam13499   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)CHP1
PDB (RSDB)2.00E+30   
PDB Europe2.00E+30   
PDB (PDBSum)2.00E+30   
PDB (IMB)2.00E+30   
Structural Biology KnowledgeBase2.00E+30   
SCOP (Structural Classification of Proteins)2.00E+30   
CATH (Classification of proteins structures)2.00E+30   
SuperfamilyQ99653
AlphaFold pdb e-kbQ99653   
Human Protein Atlas [tissue]ENSG00000187446-CHP1 [tissue]
HPRD06101
Protein Interaction databases
DIP (DOE-UCLA)Q99653
IntAct (EBI)Q99653
BioGRIDCHP1
STRING (EMBL)CHP1
ZODIACCHP1
Ontologies - Pathways
QuickGOQ99653
Ontology : AmiGOGolgi membrane  microtubule bundle formation  negative regulation of protein phosphorylation  protein kinase inhibitor activity  calcium ion binding  protein binding  nucleus  cytoplasm  endoplasmic reticulum  endoplasmic reticulum-Golgi intermediate compartment  cytosol  plasma membrane  plasma membrane  plasma membrane  focal adhesion  negative regulation of protein kinase activity  protein export from nucleus  potassium ion transport  vesicle targeting  vesicle fusion  small GTPase mediated signal transduction  microtubule binding  negative regulation of phosphatase activity  potassium channel regulator activity  microtubule cytoskeleton  kinase binding  membrane docking  transport vesicle  hyaluronan catabolic process  cytoplasmic microtubule organization  negative regulation of protein ubiquitination  negative regulation of protein autophosphorylation  negative regulation of NF-kappaB transcription factor activity  positive regulation of sodium:proton antiporter activity  positive regulation of sodium:proton antiporter activity  negative regulation of protein import into nucleus  calcium-dependent protein binding  protein stabilization  positive regulation of protein transport  protein complex oligomerization  regulation of intracellular pH  positive regulation of protein glycosylation  membrane organization  membrane fusion  extracellular exosome  negative regulation of calcineurin-NFAT signaling cascade  positive regulation of phospholipid biosynthetic process  cellular response to acidic pH  positive regulation of protein targeting to membrane  regulation of neuron death  
Ontology : EGO-EBIGolgi membrane  microtubule bundle formation  negative regulation of protein phosphorylation  protein kinase inhibitor activity  calcium ion binding  protein binding  nucleus  cytoplasm  endoplasmic reticulum  endoplasmic reticulum-Golgi intermediate compartment  cytosol  plasma membrane  plasma membrane  plasma membrane  focal adhesion  negative regulation of protein kinase activity  protein export from nucleus  potassium ion transport  vesicle targeting  vesicle fusion  small GTPase mediated signal transduction  microtubule binding  negative regulation of phosphatase activity  potassium channel regulator activity  microtubule cytoskeleton  kinase binding  membrane docking  transport vesicle  hyaluronan catabolic process  cytoplasmic microtubule organization  negative regulation of protein ubiquitination  negative regulation of protein autophosphorylation  negative regulation of NF-kappaB transcription factor activity  positive regulation of sodium:proton antiporter activity  positive regulation of sodium:proton antiporter activity  negative regulation of protein import into nucleus  calcium-dependent protein binding  protein stabilization  positive regulation of protein transport  protein complex oligomerization  regulation of intracellular pH  positive regulation of protein glycosylation  membrane organization  membrane fusion  extracellular exosome  negative regulation of calcineurin-NFAT signaling cascade  positive regulation of phospholipid biosynthetic process  cellular response to acidic pH  positive regulation of protein targeting to membrane  regulation of neuron death  
NDEx NetworkCHP1
Atlas of Cancer Signalling NetworkCHP1
Wikipedia pathwaysCHP1
Orthology - Evolution
OrthoDB11261
GeneTree (enSembl)ENSG00000187446
Phylogenetic Trees/Animal Genes : TreeFamCHP1
Homologs : HomoloGeneCHP1
Homology/Alignments : Family Browser (UCSC)CHP1
Gene fusions - Rearrangements
Fusion : QuiverCHP1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHP1
dbVarCHP1
ClinVarCHP1
MonarchCHP1
1000_GenomesCHP1 
Exome Variant ServerCHP1
GNOMAD BrowserENSG00000187446
Varsome BrowserCHP1
ACMGCHP1 variants
VarityQ99653
Genomic Variants (DGV)CHP1 [DGVbeta]
DECIPHERCHP1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHP1 
Mutations
ICGC Data PortalCHP1 
TCGA Data PortalCHP1 
Broad Tumor PortalCHP1
OASIS PortalCHP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHP1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCHP1
Mutations and Diseases : HGMDCHP1
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCHP1
DgiDB (Drug Gene Interaction Database)CHP1
DoCM (Curated mutations)CHP1
CIViC (Clinical Interpretations of Variants in Cancer)CHP1
Cancer3DCHP1
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606988    618438   
Orphanet
DisGeNETCHP1
MedgenCHP1
Genetic Testing Registry CHP1
NextProtQ99653 [Medical]
GENETestsCHP1
Target ValidationCHP1
Huge Navigator CHP1 [HugePedia]
ClinGenCHP1
Clinical trials, drugs, therapy
MyCancerGenomeCHP1
Protein Interactions : CTDCHP1
Pharm GKB GenePA166048950
PharosQ99653
Clinical trialCHP1
Miscellaneous
canSAR (ICR)CHP1
HarmonizomeCHP1
DataMed IndexCHP1
Probes
Litterature
PubMed63 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCHP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:03:55 CEST 2021

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