CHPF (chondroitin polymerizing factor)

2011-08-01  

Identity

HGNC
LOCATION
2q35
LOCUSID
ALIAS
CHSY2,CSS2

Other Information

Locus ID:

NCBI: 79586
MIM: 610405
HGNC: 24291
Ensembl: ENSG00000123989

Variants:

dbSNP: 79586
ClinVar: 79586
TCGA: ENSG00000123989
COSMIC: CHPF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000123989ENST00000243776Q8IZ52
ENSG00000123989ENST00000373891F8W6H2
ENSG00000123989ENST00000535926Q8IZ52

Expression (GTEx)

0
50
100
150
200
250

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGko00532
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGhsa00532
Metabolic pathwaysKEGGhsa01100
Glycosaminoglycan biosynthesis, chondroitin sulfate backboneKEGGhsa_M00058
Glycosaminoglycan biosynthesis, chondroitin sulfate backboneKEGGM00058
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Chondroitin sulfate/dermatan sulfate metabolismREACTOMER-HSA-1793185
Chondroitin sulfate biosynthesisREACTOMER-HSA-2022870

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
381902702024MiR-214-3p overexpression-triggered chondroitin polymerizing factor (CHPF) inhibition modulates the ferroptosis and metabolism in colon cancer.0
382677312024Activation of CHPF by transcription factor NFIC promotes NLRP3 activation during the progression of colorectal cancer.0
387750312024Chondroitin polymerizing factor promotes development and progression of colorectal cancer via facilitating transcription of VEGFB.1
381902702024MiR-214-3p overexpression-triggered chondroitin polymerizing factor (CHPF) inhibition modulates the ferroptosis and metabolism in colon cancer.0
382677312024Activation of CHPF by transcription factor NFIC promotes NLRP3 activation during the progression of colorectal cancer.0
387750312024Chondroitin polymerizing factor promotes development and progression of colorectal cancer via facilitating transcription of VEGFB.1
371561852023Extracellular vesicles derived from hypoxic HTR-8/SVneo trophoblast inhibit endothelial cell functions through the miR-150-3p /CHPF pathway.1
378513642023The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.0
371561852023Extracellular vesicles derived from hypoxic HTR-8/SVneo trophoblast inhibit endothelial cell functions through the miR-150-3p /CHPF pathway.1
378513642023The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma.0
333016432021Chondroitin polymerizing factor promotes breast carcinoma cell proliferation, invasion and migration and affects expression of epithelial-mesenchymal transition-related markers.6
336516572021Identification of chondroitin polymerizing factor (CHPF) as tumor promotor in cholangiocarcinoma through regulating cell proliferation, cell apoptosis and cell migration.4
345647112021CHPF promotes gastric cancer tumorigenesis through the activation of E2F1.15
333016432021Chondroitin polymerizing factor promotes breast carcinoma cell proliferation, invasion and migration and affects expression of epithelial-mesenchymal transition-related markers.6
336516572021Identification of chondroitin polymerizing factor (CHPF) as tumor promotor in cholangiocarcinoma through regulating cell proliferation, cell apoptosis and cell migration.4

Citation

Dessen P

CHPF (chondroitin polymerizing factor)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52317/chpf