CHPF2 (chondroitin polymerizing factor 2)

2011-08-01  

Identity

HGNC
LOCATION
7q36.1
LOCUSID
ALIAS
CSGLCA-T,CSGlcAT,ChSy-3,chPF-2
FUSION GENES

Other Information

Locus ID:

NCBI: 54480
MIM: 608037
HGNC: 29270
Ensembl: ENSG00000033100

Variants:

dbSNP: 54480
ClinVar: 54480
TCGA: ENSG00000033100
COSMIC: CHPF2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000033100ENST00000035307Q9P2E5
ENSG00000033100ENST00000465601H7C5L5
ENSG00000033100ENST00000482173C9JZF7
ENSG00000033100ENST00000495645G5E9W2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGko00532
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGhsa00532
Metabolic pathwaysKEGGhsa01100
Glycosaminoglycan biosynthesis, chondroitin sulfate backboneKEGGhsa_M00058
Glycosaminoglycan biosynthesis, chondroitin sulfate backboneKEGGM00058
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Chondroitin sulfate/dermatan sulfate metabolismREACTOMER-HSA-1793185
Chondroitin sulfate biosynthesisREACTOMER-HSA-2022870

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
183163762008Identification of chondroitin sulfate glucuronyltransferase as chondroitin synthase-3 involved in chondroitin polymerization: chondroitin polymerization is achieved by multiple enzyme complexes consisting of chondroitin synthase family members.35
121452782002Molecular cloning and characterization of a novel chondroitin sulfate glucuronyltransferase that transfers glucuronic acid to N-acetylgalactosamine.14
214685782011Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer.12

Citation

Dessen P

CHPF2 (chondroitin polymerizing factor 2)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52307/chpf2