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CHRD (chordin)

Identity

Other alias-
HGNC (Hugo) CHRD
LocusID (NCBI) 8646
Atlas_Id 43607
Location 3q27.1  [Link to chromosome band 3q27]
Location_base_pair Starts at 184380073 and ends at 184389835 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PQLC2L (3q25.32) / CHRD (3q27.1)C3orf55 CHRD 3q27.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CHRD   1949
Cards
Entrez_Gene (NCBI)CHRD  8646  chordin
Aliases
GeneCards (Weizmann)CHRD
Ensembl hg19 (Hinxton)ENSG00000090539 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000090539 [Gene_View]  chr3:184380073-184389835 [Contig_View]  CHRD [Vega]
ICGC DataPortalENSG00000090539
TCGA cBioPortalCHRD
AceView (NCBI)CHRD
Genatlas (Paris)CHRD
WikiGenes8646
SOURCE (Princeton)CHRD
Genetics Home Reference (NIH)CHRD
Genomic and cartography
GoldenPath hg38 (UCSC)CHRD  -     chr3:184380073-184389835 +  3q27.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHRD  -     3q27.1   [Description]    (hg19-Feb_2009)
EnsemblCHRD - 3q27.1 [CytoView hg19]  CHRD - 3q27.1 [CytoView hg38]
Mapping of homologs : NCBICHRD [Mapview hg19]  CHRD [Mapview hg38]
OMIM603475   
Gene and transcription
Genbank (Entrez)AB208947 AF038198 AF076612 AF209928 AF209929
RefSeq transcript (Entrez)NM_001304472 NM_001304473 NM_001304474 NM_003741 NM_177978 NM_177979
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CHRD
Cluster EST : UnigeneHs.166186 [ NCBI ]
CGAP (NCI)Hs.166186
Alternative Splicing GalleryENSG00000090539
Gene ExpressionCHRD [ NCBI-GEO ]   CHRD [ EBI - ARRAY_EXPRESS ]   CHRD [ SEEK ]   CHRD [ MEM ]
Gene Expression Viewer (FireBrowse)CHRD [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8646
GTEX Portal (Tissue expression)CHRD
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H2X0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H2X0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H2X0
Splice isoforms : SwissVarQ9H2X0
PhosPhoSitePlusQ9H2X0
Domaine pattern : Prosite (Expaxy)CHRD (PS50933)    VWFC_1 (PS01208)    VWFC_2 (PS50184)   
Domains : Interpro (EBI)Chordin    CHRD    VWF_dom   
Domain families : Pfam (Sanger)CHRD (PF07452)    VWC (PF00093)   
Domain families : Pfam (NCBI)pfam07452    pfam00093   
Domain families : Smart (EMBL)CHRD (SM00754)  VWC (SM00214)  
Conserved Domain (NCBI)CHRD
DMDM Disease mutations8646
Blocks (Seattle)CHRD
SuperfamilyQ9H2X0
Human Protein AtlasENSG00000090539
Peptide AtlasQ9H2X0
HPRD04592
IPIIPI00306710   IPI00221160   IPI00221161   IPI00221162   IPI00719497   IPI00921914   IPI00555959   IPI00179013   IPI00924496   
Protein Interaction databases
DIP (DOE-UCLA)Q9H2X0
IntAct (EBI)Q9H2X0
FunCoupENSG00000090539
BioGRIDCHRD
STRING (EMBL)CHRD
ZODIACCHRD
Ontologies - Pathways
QuickGOQ9H2X0
Ontology : AmiGOskeletal system development  osteoblast differentiation  gastrulation with mouth forming second  mesoderm formation  positive regulation of mesenchymal cell proliferation  protein binding  extracellular space  heparin binding  cytokine binding  BMP signaling pathway involved in spinal cord dorsal/ventral patterning  negative regulation of cell migration  negative regulation of BMP signaling pathway  forebrain development  floor plate development  syndecan binding  negative regulation of osteoblast differentiation  positive regulation of cell adhesion  
Ontology : EGO-EBIskeletal system development  osteoblast differentiation  gastrulation with mouth forming second  mesoderm formation  positive regulation of mesenchymal cell proliferation  protein binding  extracellular space  heparin binding  cytokine binding  BMP signaling pathway involved in spinal cord dorsal/ventral patterning  negative regulation of cell migration  negative regulation of BMP signaling pathway  forebrain development  floor plate development  syndecan binding  negative regulation of osteoblast differentiation  positive regulation of cell adhesion  
Pathways : BIOCARTAALK in cardiac myocytes [Genes]   
Pathways : KEGGTGF-beta signaling pathway   
NDEx NetworkCHRD
Atlas of Cancer Signalling NetworkCHRD
Wikipedia pathwaysCHRD
Orthology - Evolution
OrthoDB8646
GeneTree (enSembl)ENSG00000090539
Phylogenetic Trees/Animal Genes : TreeFamCHRD
HOVERGENQ9H2X0
HOGENOMQ9H2X0
Homologs : HomoloGeneCHRD
Homology/Alignments : Family Browser (UCSC)CHRD
Gene fusions - Rearrangements
Fusion : MitelmanPQLC2L/CHRD [3q25.32/3q27.1]  [t(3;3)(q25;q27)]  
Fusion: TCGAC3orf55 CHRD 3q27.1 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHRD [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHRD
dbVarCHRD
ClinVarCHRD
1000_GenomesCHRD 
Exome Variant ServerCHRD
ExAC (Exome Aggregation Consortium)CHRD (select the gene name)
Genetic variants : HAPMAP8646
Genomic Variants (DGV)CHRD [DGVbeta]
DECIPHERCHRD [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHRD 
Mutations
ICGC Data PortalCHRD 
TCGA Data PortalCHRD 
Broad Tumor PortalCHRD
OASIS PortalCHRD [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHRD  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCHRD
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CHRD
DgiDB (Drug Gene Interaction Database)CHRD
DoCM (Curated mutations)CHRD (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHRD (select a term)
intoGenCHRD
Cancer3DCHRD(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603475   
Orphanet
MedgenCHRD
Genetic Testing Registry CHRD
NextProtQ9H2X0 [Medical]
TSGene8646
GENETestsCHRD
Huge Navigator CHRD [HugePedia]
snp3D : Map Gene to Disease8646
BioCentury BCIQCHRD
ClinGenCHRD
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8646
Chemical/Pharm GKB GenePA26482
Clinical trialCHRD
Miscellaneous
canSAR (ICR)CHRD (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHRD
EVEXCHRD
GoPubMedCHRD
iHOPCHRD
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:10:34 CEST 2017

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