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CHRDL2 (chordin like 2)

Identity

Alias_symbol (synonym)BNF1
Other aliasCHL2
HGNC (Hugo) CHRDL2
LocusID (NCBI) 25884
Atlas_Id 40080
Location 11q13.4  [Link to chromosome band 11q13]
Location_base_pair Starts at 74696428 and ends at 74731385 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ERP44 (9q31.1) / CHRDL2 (11q13.4)PIGG (4p16.3) / CHRDL2 (11q13.4)ERP44 9q31.1 / CHRDL2 11q13.4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(9;11)(q31;q13) ERP44/CHRDL2


External links

Nomenclature
HGNC (Hugo)CHRDL2   24168
Cards
Entrez_Gene (NCBI)CHRDL2  25884  chordin like 2
AliasesBNF1; CHL2
GeneCards (Weizmann)CHRDL2
Ensembl hg19 (Hinxton)ENSG00000054938 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000054938 [Gene_View]  ENSG00000054938 [Sequence]  chr11:74696428-74731385 [Contig_View]  CHRDL2 [Vega]
ICGC DataPortalENSG00000054938
TCGA cBioPortalCHRDL2
AceView (NCBI)CHRDL2
Genatlas (Paris)CHRDL2
WikiGenes25884
SOURCE (Princeton)CHRDL2
Genetics Home Reference (NIH)CHRDL2
Genomic and cartography
GoldenPath hg38 (UCSC)CHRDL2  -     chr11:74696428-74731385 -  11q13.4   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHRDL2  -     11q13.4   [Description]    (hg19-Feb_2009)
GoldenPathCHRDL2 - 11q13.4 [CytoView hg19]  CHRDL2 - 11q13.4 [CytoView hg38]
ImmunoBaseENSG00000054938
Mapping of homologs : NCBICHRDL2 [Mapview hg19]  CHRDL2 [Mapview hg38]
OMIM613127   
Gene and transcription
Genbank (Entrez)AF332891 AK304519 AL047873 AL110168 AY163868
RefSeq transcript (Entrez)NM_001278473 NM_001304390 NM_001304391 NM_001304415 NM_001304416 NM_001304417 NM_015424
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CHRDL2
Cluster EST : UnigeneHs.432379 [ NCBI ]
CGAP (NCI)Hs.432379
Alternative Splicing GalleryENSG00000054938
Gene ExpressionCHRDL2 [ NCBI-GEO ]   CHRDL2 [ EBI - ARRAY_EXPRESS ]   CHRDL2 [ SEEK ]   CHRDL2 [ MEM ]
Gene Expression Viewer (FireBrowse)CHRDL2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25884
GTEX Portal (Tissue expression)CHRDL2
Human Protein AtlasENSG00000054938-CHRDL2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6WN34   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6WN34  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6WN34
Splice isoforms : SwissVarQ6WN34
PhosPhoSitePlusQ6WN34
Domaine pattern : Prosite (Expaxy)VWFC_1 (PS01208)    VWFC_2 (PS50184)   
Domains : Interpro (EBI)VWF_dom   
Domain families : Pfam (Sanger)VWC (PF00093)   
Domain families : Pfam (NCBI)pfam00093   
Domain families : Smart (EMBL)VWC (SM00214)  
Conserved Domain (NCBI)CHRDL2
DMDM Disease mutations25884
Blocks (Seattle)CHRDL2
SuperfamilyQ6WN34
Human Protein Atlas [tissue]ENSG00000054938-CHRDL2 [tissue]
Peptide AtlasQ6WN34
HPRD09881
IPIIPI00449244   IPI00307781   IPI00449239   IPI00449238   IPI00983254   IPI00908547   IPI00976199   IPI00449242   IPI01019089   IPI00984579   IPI00555793   
Protein Interaction databases
DIP (DOE-UCLA)Q6WN34
IntAct (EBI)Q6WN34
FunCoupENSG00000054938
BioGRIDCHRDL2
STRING (EMBL)CHRDL2
ZODIACCHRDL2
Ontologies - Pathways
QuickGOQ6WN34
Ontology : AmiGOossification  extracellular space  cytoplasm  cell differentiation  cartilage development  
Ontology : EGO-EBIossification  extracellular space  cytoplasm  cell differentiation  cartilage development  
NDEx NetworkCHRDL2
Atlas of Cancer Signalling NetworkCHRDL2
Wikipedia pathwaysCHRDL2
Orthology - Evolution
OrthoDB25884
GeneTree (enSembl)ENSG00000054938
Phylogenetic Trees/Animal Genes : TreeFamCHRDL2
HOGENOMQ6WN34
Homologs : HomoloGeneCHRDL2
Homology/Alignments : Family Browser (UCSC)CHRDL2
Gene fusions - Rearrangements
Fusion : MitelmanERP44/CHRDL2 [9q31.1/11q13.4]  [t(9;11)(q31;q13)]  
Fusion PortalERP44 9q31.1 CHRDL2 11q13.4 HNSC
Fusion : QuiverCHRDL2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHRDL2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHRDL2
dbVarCHRDL2
ClinVarCHRDL2
1000_GenomesCHRDL2 
Exome Variant ServerCHRDL2
ExAC (Exome Aggregation Consortium)ENSG00000054938
GNOMAD BrowserENSG00000054938
Varsome BrowserCHRDL2
Genetic variants : HAPMAP25884
Genomic Variants (DGV)CHRDL2 [DGVbeta]
DECIPHERCHRDL2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHRDL2 
Mutations
ICGC Data PortalCHRDL2 
TCGA Data PortalCHRDL2 
Broad Tumor PortalCHRDL2
OASIS PortalCHRDL2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHRDL2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCHRDL2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CHRDL2
DgiDB (Drug Gene Interaction Database)CHRDL2
DoCM (Curated mutations)CHRDL2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHRDL2 (select a term)
intoGenCHRDL2
Cancer3DCHRDL2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613127   
Orphanet
DisGeNETCHRDL2
MedgenCHRDL2
Genetic Testing Registry CHRDL2
NextProtQ6WN34 [Medical]
TSGene25884
GENETestsCHRDL2
Target ValidationCHRDL2
Huge Navigator CHRDL2 [HugePedia]
snp3D : Map Gene to Disease25884
BioCentury BCIQCHRDL2
ClinGenCHRDL2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25884
Chemical/Pharm GKB GenePA134883081
Clinical trialCHRDL2
Miscellaneous
canSAR (ICR)CHRDL2 (select the gene name)
DataMed IndexCHRDL2
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHRDL2
EVEXCHRDL2
GoPubMedCHRDL2
iHOPCHRDL2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Jul 8 11:14:57 CEST 2019

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