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CHRM5 (cholinergic receptor muscarinic 5)

Identity

Alias_namesmuscarinic 5
Other aliasHM5
HGNC (Hugo) CHRM5
LocusID (NCBI) 1133
Atlas_Id 56099
Location 15q14  [Link to chromosome band 15q14]
Location_base_pair Starts at 33968314 and ends at 34065094 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CHRM5   1954
Cards
Entrez_Gene (NCBI)CHRM5  1133  cholinergic receptor muscarinic 5
AliasesHM5
GeneCards (Weizmann)CHRM5
Ensembl hg19 (Hinxton)ENSG00000184984 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184984 [Gene_View]  chr15:33968314-34065094 [Contig_View]  CHRM5 [Vega]
ICGC DataPortalENSG00000184984
TCGA cBioPortalCHRM5
AceView (NCBI)CHRM5
Genatlas (Paris)CHRM5
WikiGenes1133
SOURCE (Princeton)CHRM5
Genetics Home Reference (NIH)CHRM5
Genomic and cartography
GoldenPath hg38 (UCSC)CHRM5  -     chr15:33968314-34065094 +  15q14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHRM5  -     15q14   [Description]    (hg19-Feb_2009)
EnsemblCHRM5 - 15q14 [CytoView hg19]  CHRM5 - 15q14 [CytoView hg38]
Mapping of homologs : NCBICHRM5 [Mapview hg19]  CHRM5 [Mapview hg38]
OMIM118496   
Gene and transcription
Genbank (Entrez)AB084282 AF026263 AF385591 AF498919 AK095198
RefSeq transcript (Entrez)NM_001320917 NM_012125
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CHRM5
Cluster EST : UnigeneHs.584747 [ NCBI ]
CGAP (NCI)Hs.584747
Alternative Splicing GalleryENSG00000184984
Gene ExpressionCHRM5 [ NCBI-GEO ]   CHRM5 [ EBI - ARRAY_EXPRESS ]   CHRM5 [ SEEK ]   CHRM5 [ MEM ]
Gene Expression Viewer (FireBrowse)CHRM5 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1133
GTEX Portal (Tissue expression)CHRM5
Protein : pattern, domain, 3D structure
UniProt/SwissProtP08912   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP08912  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP08912
Splice isoforms : SwissVarP08912
PhosPhoSitePlusP08912
Domaine pattern : Prosite (Expaxy)G_PROTEIN_RECEP_F1_1 (PS00237)    G_PROTEIN_RECEP_F1_2 (PS50262)   
Domains : Interpro (EBI)GPCR_Rhodpsn    GPCR_Rhodpsn_7TM    Musac_Ach_M5_rcpt    Musac_Ach_rcpt   
Domain families : Pfam (Sanger)7tm_1 (PF00001)   
Domain families : Pfam (NCBI)pfam00001   
Conserved Domain (NCBI)CHRM5
DMDM Disease mutations1133
Blocks (Seattle)CHRM5
SuperfamilyP08912
Human Protein AtlasENSG00000184984
Peptide AtlasP08912
HPRD00331
IPIIPI00031710   IPI00982928   
Protein Interaction databases
DIP (DOE-UCLA)P08912
IntAct (EBI)P08912
FunCoupENSG00000184984
BioGRIDCHRM5
STRING (EMBL)CHRM5
ZODIACCHRM5
Ontologies - Pathways
QuickGOP08912
Ontology : AmiGOgastric acid secretion  phosphatidylinositol phospholipase C activity  plasma membrane  integral component of plasma membrane  adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway  phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway  G-protein coupled acetylcholine receptor signaling pathway  synaptic transmission, cholinergic  cell proliferation  dopamine transport  G-protein coupled acetylcholine receptor activity  transmission of nerve impulse  cell junction  synapse  postsynaptic membrane  regulation of phosphatidylinositol dephosphorylation  
Ontology : EGO-EBIgastric acid secretion  phosphatidylinositol phospholipase C activity  plasma membrane  integral component of plasma membrane  adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway  phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway  G-protein coupled acetylcholine receptor signaling pathway  synaptic transmission, cholinergic  cell proliferation  dopamine transport  G-protein coupled acetylcholine receptor activity  transmission of nerve impulse  cell junction  synapse  postsynaptic membrane  regulation of phosphatidylinositol dephosphorylation  
Pathways : KEGGCalcium signaling pathway    Neuroactive ligand-receptor interaction    Cholinergic synapse    Regulation of actin cytoskeleton   
NDEx NetworkCHRM5
Atlas of Cancer Signalling NetworkCHRM5
Wikipedia pathwaysCHRM5
Orthology - Evolution
OrthoDB1133
GeneTree (enSembl)ENSG00000184984
Phylogenetic Trees/Animal Genes : TreeFamCHRM5
HOVERGENP08912
HOGENOMP08912
Homologs : HomoloGeneCHRM5
Homology/Alignments : Family Browser (UCSC)CHRM5
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHRM5 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHRM5
dbVarCHRM5
ClinVarCHRM5
1000_GenomesCHRM5 
Exome Variant ServerCHRM5
ExAC (Exome Aggregation Consortium)CHRM5 (select the gene name)
Genetic variants : HAPMAP1133
Genomic Variants (DGV)CHRM5 [DGVbeta]
DECIPHERCHRM5 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHRM5 
Mutations
ICGC Data PortalCHRM5 
TCGA Data PortalCHRM5 
Broad Tumor PortalCHRM5
OASIS PortalCHRM5 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHRM5  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCHRM5
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CHRM5
DgiDB (Drug Gene Interaction Database)CHRM5
DoCM (Curated mutations)CHRM5 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHRM5 (select a term)
intoGenCHRM5
Cancer3DCHRM5(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118496   
Orphanet
MedgenCHRM5
Genetic Testing Registry CHRM5
NextProtP08912 [Medical]
TSGene1133
GENETestsCHRM5
Huge Navigator CHRM5 [HugePedia]
snp3D : Map Gene to Disease1133
BioCentury BCIQCHRM5
ClinGenCHRM5
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1133
Chemical/Pharm GKB GenePA26486
Clinical trialCHRM5
Miscellaneous
canSAR (ICR)CHRM5 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHRM5
EVEXCHRM5
GoPubMedCHRM5
iHOPCHRM5
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:10:35 CEST 2017

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