CHST12 (carbohydrate sulfotransferase 12)

2007-04-01  

Identity

HGNC
LOCATION
7p22.3
LOCUSID
ALIAS
C4S-2,C4ST-2,C4ST2
FUSION GENES

Other Information

Locus ID:

NCBI: 55501
MIM: 610129
HGNC: 17423
Ensembl: ENSG00000136213

Variants:

dbSNP: 55501
ClinVar: 55501
TCGA: ENSG00000136213
COSMIC: CHST12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000136213ENST00000258711Q9NRB3
ENSG00000136213ENST00000258711A0A024R860
ENSG00000136213ENST00000432336C9J991
ENSG00000136213ENST00000618655Q9NRB3
ENSG00000136213ENST00000618655A0A024R860

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGko00532
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGhsa00532
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Chondroitin sulfate/dermatan sulfate metabolismREACTOMER-HSA-1793185
Chondroitin sulfate biosynthesisREACTOMER-HSA-2022870

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
128470912003Specificities of three distinct human chondroitin/dermatan N-acetylgalactosamine 4-O-sulfotransferases demonstrated using partially desulfated dermatan sulfate as an acceptor: implication of differential roles in dermatan sulfate biosynthesis.26
269938262016CHST11/13 Regulate the Metastasis and Chemosensitivity of Human Hepatocellular Carcinoma Cells Via Mitogen-Activated Protein Kinase Pathway.3
205803882010Natural frequency of polymorphisms linked to the chondroitin 4-sulfotransferase genes and its association with placental malaria.0

Citation

Dessen P

CHST12 (carbohydrate sulfotransferase 12)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46971/chst12