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CHST2 (carbohydrate sulfotransferase 2)

Identity

Alias (NCBI)C6ST
GST-2
GST2
Gn6ST-1
HEL-S-75
glcNAc6ST-1
HGNC (Hugo) CHST2
HGNC Alias symbC6ST
HGNC Previous namecarbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
LocusID (NCBI) 9435
Atlas_Id 49854
Location 3q24  [Link to chromosome band 3q24]
Location_base_pair Starts at 143119771 and ends at 143124014 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CHST2 (3q24)::CLN6 (15q23)CLN6 (15q23)::CHST2 (3q24)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CHST2   1970
Cards
Entrez_Gene (NCBI)CHST2    carbohydrate sulfotransferase 2
AliasesC6ST; GST-2; GST2; Gn6ST-1; 
HEL-S-75; glcNAc6ST-1
GeneCards (Weizmann)CHST2
Ensembl hg19 (Hinxton)ENSG00000175040 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175040 [Gene_View]  ENSG00000175040 [Sequence]  chr3:143119771-143124014 [Contig_View]  CHST2 [Vega]
ICGC DataPortalENSG00000175040
TCGA cBioPortalCHST2
AceView (NCBI)CHST2
Genatlas (Paris)CHST2
SOURCE (Princeton)CHST2
Genetics Home Reference (NIH)CHST2
Genomic and cartography
GoldenPath hg38 (UCSC)CHST2  -     chr3:143119771-143124014 +  3q24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CHST2  -     3q24   [Description]    (hg19-Feb_2009)
GoldenPathCHST2 - 3q24 [CytoView hg19]  CHST2 - 3q24 [CytoView hg38]
ImmunoBaseENSG00000175040
Genome Data Viewer NCBICHST2 [Mapview hg19]  
OMIM603798   
Gene and transcription
Genbank (Entrez)AB014679 AB014680 AB021124 AF083066 AK023268
RefSeq transcript (Entrez)NM_004267
Consensus coding sequences : CCDS (NCBI)CHST2
Gene ExpressionCHST2 [ NCBI-GEO ]   CHST2 [ EBI - ARRAY_EXPRESS ]   CHST2 [ SEEK ]   CHST2 [ MEM ]
Gene Expression Viewer (FireBrowse)CHST2 [ Firebrowse - Broad ]
GenevisibleExpression of CHST2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9435
GTEX Portal (Tissue expression)CHST2
Human Protein AtlasENSG00000175040-CHST2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y4C5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y4C5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y4C5
Catalytic activity : Enzyme2.8.2.- [ Enzyme-Expasy ]   2.8.2.-2.8.2.- [ IntEnz-EBI ]   2.8.2.- [ BRENDA ]   2.8.2.- [ KEGG ]   [ MEROPS ]
PhosPhoSitePlusQ9Y4C5
Domains : Interpro (EBI)Carbohydrate_sulfotransferase    P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
Conserved Domain (NCBI)CHST2
SuperfamilyQ9Y4C5
AlphaFold pdb e-kbQ9Y4C5   
Human Protein Atlas [tissue]ENSG00000175040-CHST2 [tissue]
HPRD04814
Protein Interaction databases
DIP (DOE-UCLA)Q9Y4C5
IntAct (EBI)Q9Y4C5
BioGRIDCHST2
STRING (EMBL)CHST2
ZODIACCHST2
Ontologies - Pathways
QuickGOQ9Y4C5
Ontology : AmiGOGolgi membrane  N-acetylglucosamine 6-O-sulfotransferase activity  N-acetylglucosamine 6-O-sulfotransferase activity  nucleoplasm  Golgi apparatus  trans-Golgi network  trans-Golgi network  cytosol  carbohydrate metabolic process  N-acetylglucosamine metabolic process  N-acetylglucosamine metabolic process  sulfur compound metabolic process  sulfur compound metabolic process  inflammatory response  multicellular organism development  sulfotransferase activity  integral component of membrane  keratan sulfate biosynthetic process  intrinsic component of Golgi membrane  
Ontology : EGO-EBIGolgi membrane  N-acetylglucosamine 6-O-sulfotransferase activity  N-acetylglucosamine 6-O-sulfotransferase activity  nucleoplasm  Golgi apparatus  trans-Golgi network  trans-Golgi network  cytosol  carbohydrate metabolic process  N-acetylglucosamine metabolic process  N-acetylglucosamine metabolic process  sulfur compound metabolic process  sulfur compound metabolic process  inflammatory response  multicellular organism development  sulfotransferase activity  integral component of membrane  keratan sulfate biosynthetic process  intrinsic component of Golgi membrane  
Pathways : KEGGGlycosaminoglycan biosynthesis - keratan sulfate   
NDEx NetworkCHST2
Atlas of Cancer Signalling NetworkCHST2
Wikipedia pathwaysCHST2
Orthology - Evolution
OrthoDB9435
GeneTree (enSembl)ENSG00000175040
Phylogenetic Trees/Animal Genes : TreeFamCHST2
Homologs : HomoloGeneCHST2
Homology/Alignments : Family Browser (UCSC)CHST2
Gene fusions - Rearrangements
Fusion : QuiverCHST2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCHST2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHST2
dbVarCHST2
ClinVarCHST2
MonarchCHST2
1000_GenomesCHST2 
Exome Variant ServerCHST2
GNOMAD BrowserENSG00000175040
Varsome BrowserCHST2
ACMGCHST2 variants
VarityQ9Y4C5
Genomic Variants (DGV)CHST2 [DGVbeta]
DECIPHERCHST2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCHST2 
Mutations
ICGC Data PortalCHST2 
TCGA Data PortalCHST2 
Broad Tumor PortalCHST2
OASIS PortalCHST2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCHST2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCHST2
Mutations and Diseases : HGMDCHST2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCHST2
DgiDB (Drug Gene Interaction Database)CHST2
DoCM (Curated mutations)CHST2
CIViC (Clinical Interpretations of Variants in Cancer)CHST2
Cancer3DCHST2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603798   
Orphanet
DisGeNETCHST2
MedgenCHST2
Genetic Testing Registry CHST2
NextProtQ9Y4C5 [Medical]
GENETestsCHST2
Target ValidationCHST2
Huge Navigator CHST2 [HugePedia]
ClinGenCHST2
Clinical trials, drugs, therapy
MyCancerGenomeCHST2
Protein Interactions : CTDCHST2
Pharm GKB GenePA26502
PharosQ9Y4C5
Clinical trialCHST2
Miscellaneous
canSAR (ICR)CHST2
HarmonizomeCHST2
ARCHS4CHST2
DataMed IndexCHST2
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCHST2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jan 17 15:19:08 CET 2022

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