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CHST4 (carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4)

Identity

Other namesGST3
GlcNAc6ST2
HECGLCNAC6ST
LSST
HGNC (Hugo) CHST4
LocusID (NCBI) 10164
Atlas_Id 46239
Location 16q22.2
Location_base_pair Starts at 71560154 and ends at 71572493 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2015)
SNTB2 16q22.1 / CHST4 16q22.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CHST4   1972
Cards
Entrez_Gene (NCBI)CHST4  10164  carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
GeneCards (Weizmann)CHST4
Ensembl hg19 (Hinxton)ENSG00000140835 [Gene_View]  chr16:71560154-71572493 [Contig_View]  CHST4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000140835 [Gene_View]  chr16:71560154-71572493 [Contig_View]  CHST4 [Vega]
ICGC DataPortalENSG00000140835
TCGA cBioPortalCHST4
AceView (NCBI)CHST4
Genatlas (Paris)CHST4
WikiGenes10164
SOURCE (Princeton)CHST4
Genomic and cartography
GoldenPath hg19 (UCSC)CHST4  -     chr16:71560154-71572493 +  16q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CHST4  -     16q22.2   [Description]    (hg38-Dec_2013)
EnsemblCHST4 - 16q22.2 [CytoView hg19]  CHST4 - 16q22.2 [CytoView hg38]
Mapping of homologs : NCBICHST4 [Mapview hg19]  CHST4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF131235 AF149783 AF280088 AK026635 AK074746
RefSeq transcript (Entrez)NM_001166395 NM_005769
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_029801 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)CHST4
Cluster EST : UnigeneHs.251383 [ NCBI ]
CGAP (NCI)Hs.251383
Alternative Splicing : Fast-db (Paris)GSHG0011334
Alternative Splicing GalleryENSG00000140835
Gene ExpressionCHST4 [ NCBI-GEO ]     CHST4 [ SEEK ]   CHST4 [ MEM ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)10164
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NCG5 (Uniprot)
NextProtQ8NCG5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NCG5
Splice isoforms : SwissVarQ8NCG5 (Swissvar)
Catalytic activity : Enzyme2.8.2.- [ Enzyme-Expasy ]   2.8.2.- [ Enzyme-SRS ]   2.8.2.- [ IntEnz-EBI ]   2.8.2.- [ PRIAM ]   2.8.2.- [ BRENDA ]   2.8.2.- [ KEGG ]   2.8.2.- [ IUBMB ]
PhosPhoSitePlusQ8NCG5
Domains : Interpro (EBI)Carbohydrate_sulfotransferase    P-loop_NTPase    Sulfotransferase_dom   
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
DMDM Disease mutations10164
Blocks (Seattle)CHST4
Human Protein AtlasENSG00000140835
Peptide AtlasQ8NCG5
HPRD07477
IPIIPI00301494   
Protein Interaction databases
DIP (DOE-UCLA)Q8NCG5
IntAct (EBI)Q8NCG5
FunCoupENSG00000140835
BioGRIDCHST4
IntegromeDBCHST4
STRING (EMBL)CHST4
ZODIACCHST4
Ontologies - Pathways
QuickGOQ8NCG5
Ontology : AmiGON-acetylglucosamine 6-O-sulfotransferase activity  trans-Golgi network  carbohydrate metabolic process  N-acetylglucosamine metabolic process  protein sulfation  sulfur compound metabolic process  movement of cell or subcellular component  inflammatory response  immune response  cell adhesion  cell-cell signaling  sulfotransferase activity  integral component of membrane  intrinsic component of Golgi membrane  
Ontology : EGO-EBIN-acetylglucosamine 6-O-sulfotransferase activity  trans-Golgi network  carbohydrate metabolic process  N-acetylglucosamine metabolic process  protein sulfation  sulfur compound metabolic process  movement of cell or subcellular component  inflammatory response  immune response  cell adhesion  cell-cell signaling  sulfotransferase activity  integral component of membrane  intrinsic component of Golgi membrane  
Pathways : KEGGGlycosaminoglycan biosynthesis - keratan sulfate   
Protein Interaction DatabaseCHST4
Atlas of Cancer Signalling NetworkCHST4
Wikipedia pathwaysCHST4
Orthology - Evolution
OrthoDB10164
GeneTree (enSembl)ENSG00000140835
Phylogenetic Trees/Animal Genes : TreeFamCHST4
Homologs : HomoloGeneCHST4
Homology/Alignments : Family Browser (UCSC)CHST4
Gene fusions - Rearrangements
Fusion: TCGASNTB2 16q22.1 CHST4 16q22.2 BRCA
Polymorphisms : SNP, variants
NCBI Variation ViewerCHST4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHST4
dbVarCHST4
ClinVarCHST4
1000_GenomesCHST4 
Exome Variant ServerCHST4
Exome Aggregation Consortium (ExAC)ENSG00000140835
SNP (GeneSNP Utah)CHST4
SNP : HGBaseCHST4
Genetic variants : HAPMAPCHST4
Genomic Variants (DGV)CHST4 [DGVbeta]
Mutations
ICGC Data PortalCHST4 
TCGA Data PortalCHST4 
Tumor PortalCHST4
TCGA Copy Number PortalCHST4
Somatic Mutations in Cancer : COSMICCHST4 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch CHST4
DgiDB (Drug Gene Interaction Database)CHST4
DoCM (Curated mutations)CHST4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CHST4 (select a term)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:71560154-71572493
CONAN: Copy Number AnalysisCHST4 
Mutations and Diseases : HGMDCHST4
OMIM
MedgenCHST4
NextProtQ8NCG5 [Medical]
TSGene10164
GENETestsCHST4
Huge Navigator CHST4 [HugePedia]  CHST4 [HugeCancerGEM]
snp3D : Map Gene to Disease10164
BioCentury BCIQCHST4
General knowledge
Chemical/Protein Interactions : CTD10164
Chemical/Pharm GKB GenePA26504
Clinical trialCHST4
Other databases
Probes
Litterature
PubMed23 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCHST4
GoPubMedCHST4
iHOPCHST4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jan 16 18:21:10 CET 2016

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