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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret jlhuret@AtlasGeneticsOncology.org
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

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CHST4 (carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4)

Identity

Other namesGST3
GlcNAc6ST2
HECGLCNAC6ST
LSST
HGNC (Hugo) CHST4
LocusID (NCBI) 10164
Location 16q22.2
Location_base_pair Starts at 71560154 and ends at 71572493 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CHST4   1972
Cards
Entrez_Gene (NCBI)CHST4  10164  carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
GeneCards (Weizmann)CHST4
Ensembl hg19 (Hinxton)ENSG00000140835 [Gene_View]  chr16:71560154-71572493 [Contig_View]  CHST4 [Vega]
Ensembl hg38 (Hinxton)ENSG00000140835 [Gene_View]  chr16:71560154-71572493 [Contig_View]  CHST4 [Vega]
ICGC DataPortalENSG00000140835
cBioPortalCHST4
AceView (NCBI)CHST4
Genatlas (Paris)CHST4
WikiGenes10164
SOURCE (Princeton)CHST4
Genomic and cartography
GoldenPath hg19 (UCSC)CHST4  -     chr16:71560154-71572493 +  16q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CHST4  -     16q22.2   [Description]    (hg38-Dec_2013)
EnsemblCHST4 - 16q22.2 [CytoView hg19]  CHST4 - 16q22.2 [CytoView hg38]
Mapping of homologs : NCBICHST4 [Mapview hg19]  CHST4 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF131235 AF149783 AF280088 AK026635 AK074746
RefSeq transcript (Entrez)NM_001166395 NM_005769
RefSeq genomic (Entrez)NC_000016 NC_018927 NG_029801 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)CHST4
Cluster EST : UnigeneHs.251383 [ NCBI ]
CGAP (NCI)Hs.251383
Alternative Splicing : Fast-db (Paris)GSHG0011334
Alternative Splicing GalleryENSG00000140835
Gene ExpressionCHST4 [ NCBI-GEO ]     CHST4 [ SEEK ]   CHST4 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NCG5 (Uniprot)
NextProtQ8NCG5  [Medical]
With graphics : InterProQ8NCG5
Splice isoforms : SwissVarQ8NCG5 (Swissvar)
Catalytic activity : Enzyme2.8.2.- [ Enzyme-Expasy ]   2.8.2.-2.8.2.- [ IntEnz-EBI ]   2.8.2.- [ BRENDA ]   2.8.2.- [ KEGG ]   
Domains : Interpro (EBI)Carbohydrate_sulfotransferase    P-loop_NTPase    Sulfotransferase_dom   
Related proteins : CluSTrQ8NCG5
Domain families : Pfam (Sanger)Sulfotransfer_1 (PF00685)   
Domain families : Pfam (NCBI)pfam00685   
DMDM Disease mutations10164
Blocks (Seattle)Q8NCG5
Human Protein AtlasENSG00000140835
Peptide AtlasQ8NCG5
HPRD07477
IPIIPI00301494   
Protein Interaction databases
DIP (DOE-UCLA)Q8NCG5
IntAct (EBI)Q8NCG5
FunCoupENSG00000140835
BioGRIDCHST4
IntegromeDBCHST4
STRING (EMBL)CHST4
Ontologies - Pathways
QuickGOQ8NCG5
Ontology : AmiGON-acetylglucosamine 6-O-sulfotransferase activity  trans-Golgi network  carbohydrate metabolic process  N-acetylglucosamine metabolic process  protein sulfation  sulfur compound metabolic process  movement of cell or subcellular component  inflammatory response  immune response  cell adhesion  cell-cell signaling  sulfotransferase activity  integral component of membrane  intrinsic component of Golgi membrane  leukocyte tethering or rolling  
Ontology : EGO-EBIN-acetylglucosamine 6-O-sulfotransferase activity  trans-Golgi network  carbohydrate metabolic process  N-acetylglucosamine metabolic process  protein sulfation  sulfur compound metabolic process  movement of cell or subcellular component  inflammatory response  immune response  cell adhesion  cell-cell signaling  sulfotransferase activity  integral component of membrane  intrinsic component of Golgi membrane  leukocyte tethering or rolling  
Pathways : KEGGGlycosaminoglycan biosynthesis - keratan sulfate   
Protein Interaction DatabaseCHST4
DoCM (Curated mutations)CHST4
Wikipedia pathwaysCHST4
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCHST4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CHST4
dbVarCHST4
ClinVarCHST4
1000_GenomesCHST4 
Exome Variant ServerCHST4
SNP (GeneSNP Utah)CHST4
SNP : HGBaseCHST4
Genetic variants : HAPMAPCHST4
Genomic Variants (DGV)CHST4 [DGVbeta]
Mutations
ICGC Data PortalENSG00000140835 
Somatic Mutations in Cancer : COSMICCHST4 
CONAN: Copy Number AnalysisCHST4 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)16:71560154-71572493
Mutations and Diseases : HGMDCHST4
OMIM
MedgenCHST4
NextProtQ8NCG5 [Medical]
GENETestsCHST4
Disease Genetic AssociationCHST4
Huge Navigator CHST4 [HugePedia]  CHST4 [HugeCancerGEM]
snp3D : Map Gene to Disease10164
DGIdb (Drug Gene Interaction db)CHST4
General knowledge
Homologs : HomoloGeneCHST4
Homology/Alignments : Family Browser (UCSC)CHST4
Phylogenetic Trees/Animal Genes : TreeFamCHST4
Chemical/Protein Interactions : CTD10164
Chemical/Pharm GKB GenePA26504
Clinical trialCHST4
Cancer Resource (Charite)ENSG00000140835
Other databases
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
CoreMineCHST4
GoPubMedCHST4
iHOPCHST4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 15:02:59 CET 2015

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jlhuret@AtlasGeneticsOncology.org.