CHSY3 (chondroitin sulfate synthase 3)

2011-08-01  

Identity

HGNC
CHSY3
LOCATION
5q23.3
LOCUSID
337876
ALIAS
CHSY2,CSS3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 337876
MIM: 609963
HGNC: 24293
Ensembl: ENSG00000198108

Variants:

dbSNP: 337876
ClinVar: 337876
TCGA: ENSG00000198108
COSMIC: CHSY3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000198108ENST00000305031Q70JA7

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGko00532
Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfateKEGGhsa00532
Metabolic pathwaysKEGGhsa01100
Glycosaminoglycan biosynthesis, chondroitin sulfate backboneKEGGhsa_M00058
Glycosaminoglycan biosynthesis, chondroitin sulfate backboneKEGGM00058
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Glycosaminoglycan metabolismREACTOMER-HSA-1630316
Chondroitin sulfate/dermatan sulfate metabolismREACTOMER-HSA-1793185
Chondroitin sulfate biosynthesisREACTOMER-HSA-2022870

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
214685782011Chondroitin synthases I, II, III and chondroitin sulfate glucuronyltransferase expression in colorectal cancer.12
129076872003Chondroitin sulfate synthase-3. Molecular cloning and characterization.0
172539602007Involvement of chondroitin sulfate synthase-3 (chondroitin synthase-2) in chondroitin polymerization through its interaction with chondroitin synthase-1 or chondroitin-polymerizing factor.0

Citation

Dessen P

CHSY3 (chondroitin sulfate synthase 3)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52358/chsy3