CITED1 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1)

2003-02-01  

Identity

HGNC
CITED1
LOCATION
Xq13.1
LOCUSID
4435
ALIAS
MSG1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4435
MIM: 300149
HGNC: 1986
Ensembl: ENSG00000125931

Variants:

dbSNP: 4435
ClinVar: 4435
TCGA: ENSG00000125931
COSMIC: CITED1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000125931ENST00000246139Q99966
ENSG00000125931ENST00000373619Q99966
ENSG00000125931ENST00000417400C9JRD8
ENSG00000125931ENST00000427412C9J300
ENSG00000125931ENST00000429794H7C2S6
ENSG00000125931ENST00000431381Q99966
ENSG00000125931ENST00000445983Q99966
ENSG00000125931ENST00000450875C9J7P8
ENSG00000125931ENST00000453707Q99966
ENSG00000125931ENST00000454225C9J1P6
ENSG00000125931ENST00000651998Q99966

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Gene ExpressionREACTOMER-HSA-74160
Generic Transcription PathwayREACTOMER-HSA-212436
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factorsREACTOMER-HSA-8864260
Activation of the TFAP2 (AP-2) family of transcription factorsREACTOMER-HSA-8866907

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
211728052011TOX3 is a neuronal survival factor that induces transcription depending on the presence of CITED1 or phosphorylated CREB in the transcriptionally active complex.31
177101622007CITED1 expression in Wilms' tumor and embryonic kidney.23
227038002012SIX2 and CITED1, markers of nephronic progenitor self-renewal, remain active in primitive elements of Wilms' tumor.18
244814232014CITED1 confers stemness to Wilms tumor and enhances tumorigenic responses when enriched in the nucleus.10
214497672011Aberrant promoter methylation in overexpression of CITED1 in papillary thyroid cancer.9
168645822006The transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent manner.8
239355262013Cited1 deficiency suppresses intestinal tumorigenesis.7
237467642013Predicting lymph node metastasis in early colorectal cancer using the CITED1 expression.6

Citation

Dessen P

CITED1 (Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40086/cited1