CIZ1 (CDKN1A interacting zinc finger protein 1)

2007-02-01  

Identity

HGNC
LOCATION
9q34.11
LOCUSID
ALIAS
LSFR1,NP94,ZNF356
FUSION GENES

Other Information

Locus ID:

NCBI: 25792
MIM: 611420
HGNC: 16744
Ensembl: ENSG00000148337

Variants:

dbSNP: 25792
ClinVar: 25792
TCGA: ENSG00000148337
COSMIC: CIZ1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148337ENST00000277465Q5SYW2
ENSG00000148337ENST00000324544F6VD24
ENSG00000148337ENST00000357558Q5SYW2
ENSG00000148337ENST00000372938Q9ULV3
ENSG00000148337ENST00000372938A0A024R885
ENSG00000148337ENST00000372948Q9ULV3
ENSG00000148337ENST00000372954Q9ULV3
ENSG00000148337ENST00000393608Q9BTG3
ENSG00000148337ENST00000415526H0Y5D5
ENSG00000148337ENST00000420484F6WSM2
ENSG00000148337ENST00000471839A0A0U1RQR2
ENSG00000148337ENST00000538431F5H2X7
ENSG00000148337ENST00000629610Q9ULV3
ENSG00000148337ENST00000634901Q9ULV3
ENSG00000148337ENST00000634901A0A024R885
ENSG00000148337ENST00000651955A0A494C0L7

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
224477172012Mutations in CIZ1 cause adult onset primary cervical dystonia.56
171081412006Ciz1, a Novel DNA-binding coactivator of the estrogen receptor alpha, confers hypersensitivity to estrogen action.21
230742562012Variant Ciz1 is a circulating biomarker for early-stage lung cancer.21
289239642017Repeat E anchors Xist RNA to the inactive X chromosomal compartment through CDKN1A-interacting protein (CIZ1).18
180818652008Ciz1, a p21 cip1/Waf1-interacting zinc finger protein and DNA replication factor, is a novel molecular partner for human enhancer of rudimentary homolog.16
175084232007Cancer-associated missplicing of exon 4 influences the subnuclear distribution of the DNA replication factor CIZ1.14
185831512008Altered splicing in exon 8 of the DNA replication factor CIZ1 affects subnuclear distribution and is associated with Alzheimer's disease.14
128247002003Ciz1, Cip1 interacting zinc finger protein 1 binds the consensus DNA sequence ARYSR(0-2)YYAC.13
257362922015Cyclin-A-CDK2-mediated phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replication.11
208317842010Differential detection of alternatively spliced variants of Ciz1 in normal and cancer cells using a custom exon-junction microarray.10

Citation

Dessen P

CIZ1 (CDKN1A interacting zinc finger protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46240/ciz1