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CLASP2 (cytoplasmic linker associated protein 2)

Identity

Alias_symbol (synonym)KIAA0627
Other alias-
HGNC (Hugo) CLASP2
LocusID (NCBI) 23122
Atlas_Id 61847
Location 3p22.3  [Link to chromosome band 3p22]
Location_base_pair Starts at 33496246 and ends at 33659441 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ANXA5 (4q27) / CLASP2 (3p22.3)CLASP2 (3p22.3) / NMNAT3 (3q23)ISCU (12q23.3) / CLASP2 (3p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLASP2   17078
Cards
Entrez_Gene (NCBI)CLASP2  23122  cytoplasmic linker associated protein 2
Aliases
GeneCards (Weizmann)CLASP2
Ensembl hg19 (Hinxton)ENSG00000163539 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000163539 [Gene_View]  chr3:33496246-33659441 [Contig_View]  CLASP2 [Vega]
ICGC DataPortalENSG00000163539
TCGA cBioPortalCLASP2
AceView (NCBI)CLASP2
Genatlas (Paris)CLASP2
WikiGenes23122
SOURCE (Princeton)CLASP2
Genetics Home Reference (NIH)CLASP2
Genomic and cartography
GoldenPath hg38 (UCSC)CLASP2  -     chr3:33496246-33659441 -  3p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLASP2  -     3p22.3   [Description]    (hg19-Feb_2009)
EnsemblCLASP2 - 3p22.3 [CytoView hg19]  CLASP2 - 3p22.3 [CytoView hg38]
Mapping of homologs : NCBICLASP2 [Mapview hg19]  CLASP2 [Mapview hg38]
OMIM605853   
Gene and transcription
Genbank (Entrez)AB014527 AJ288058 AJ288059 AK024770 AK090716
RefSeq transcript (Entrez)NM_001207044 NM_015097
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLASP2
Cluster EST : UnigeneHs.108614 [ NCBI ]
CGAP (NCI)Hs.108614
Alternative Splicing GalleryENSG00000163539
Gene ExpressionCLASP2 [ NCBI-GEO ]   CLASP2 [ EBI - ARRAY_EXPRESS ]   CLASP2 [ SEEK ]   CLASP2 [ MEM ]
Gene Expression Viewer (FireBrowse)CLASP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23122
GTEX Portal (Tissue expression)CLASP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75122   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75122  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75122
Splice isoforms : SwissVarO75122
PhosPhoSitePlusO75122
Domains : Interpro (EBI)ARM-like    ARM-type_fold    CLASP_N_dom    TOG   
Domain families : Pfam (Sanger)CLASP_N (PF12348)   
Domain families : Pfam (NCBI)pfam12348   
Domain families : Smart (EMBL)TOG (SM01349)  
Conserved Domain (NCBI)CLASP2
DMDM Disease mutations23122
Blocks (Seattle)CLASP2
PDB (SRS)3WOY   
PDB (PDBSum)3WOY   
PDB (IMB)3WOY   
PDB (RSDB)3WOY   
Structural Biology KnowledgeBase3WOY   
SCOP (Structural Classification of Proteins)3WOY   
CATH (Classification of proteins structures)3WOY   
SuperfamilyO75122
Human Protein AtlasENSG00000163539
Peptide AtlasO75122
HPRD12054
IPIIPI00167067   IPI00945554   IPI00816321   IPI00925217   IPI00168165   IPI00980631   IPI00789331   IPI00871686   IPI00946716   IPI00947231   IPI00946874   IPI00789917   IPI00947416   IPI00967397   
Protein Interaction databases
DIP (DOE-UCLA)O75122
IntAct (EBI)O75122
FunCoupENSG00000163539
BioGRIDCLASP2
STRING (EMBL)CLASP2
ZODIACCLASP2
Ontologies - Pathways
QuickGOO75122
Ontology : AmiGOmicrotubule cytoskeleton organization  kinetochore  condensed chromosome kinetochore  dystroglycan binding  protein binding  cytoplasm  Golgi apparatus  trans-Golgi network  microtubule organizing center  kinetochore microtubule  cytosol  cytosol  microtubule  microtubule  cytoplasmic microtubule  plasma membrane  focal adhesion  cell cortex  vesicle targeting  microtubule nucleation  negative regulation of microtubule depolymerization  Golgi organization  mitotic spindle organization  sister chromatid cohesion  establishment or maintenance of cell polarity  microtubule binding  exit from mitosis  regulation of gastrulation  positive regulation of epithelial cell migration  regulation of epithelial to mesenchymal transition  membrane  microtubule organizing center organization  regulation of microtubule polymerization or depolymerization  cell leading edge  ruffle membrane  regulation of microtubule-based process  microtubule anchoring  basal cortex  positive regulation of exocytosis  microtubule plus-end binding  cell division  negative regulation of stress fiber assembly  negative regulation of focal adhesion assembly  mitotic spindle  establishment of protein localization to plasma membrane  positive regulation of extracellular matrix disassembly  negative regulation of wound healing, spreading of epidermal cells  positive regulation of basement membrane assembly involved in embryonic body morphogenesis  
Ontology : EGO-EBImicrotubule cytoskeleton organization  kinetochore  condensed chromosome kinetochore  dystroglycan binding  protein binding  cytoplasm  Golgi apparatus  trans-Golgi network  microtubule organizing center  kinetochore microtubule  cytosol  cytosol  microtubule  microtubule  cytoplasmic microtubule  plasma membrane  focal adhesion  cell cortex  vesicle targeting  microtubule nucleation  negative regulation of microtubule depolymerization  Golgi organization  mitotic spindle organization  sister chromatid cohesion  establishment or maintenance of cell polarity  microtubule binding  exit from mitosis  regulation of gastrulation  positive regulation of epithelial cell migration  regulation of epithelial to mesenchymal transition  membrane  microtubule organizing center organization  regulation of microtubule polymerization or depolymerization  cell leading edge  ruffle membrane  regulation of microtubule-based process  microtubule anchoring  basal cortex  positive regulation of exocytosis  microtubule plus-end binding  cell division  negative regulation of stress fiber assembly  negative regulation of focal adhesion assembly  mitotic spindle  establishment of protein localization to plasma membrane  positive regulation of extracellular matrix disassembly  negative regulation of wound healing, spreading of epidermal cells  positive regulation of basement membrane assembly involved in embryonic body morphogenesis  
NDEx NetworkCLASP2
Atlas of Cancer Signalling NetworkCLASP2
Wikipedia pathwaysCLASP2
Orthology - Evolution
OrthoDB23122
GeneTree (enSembl)ENSG00000163539
Phylogenetic Trees/Animal Genes : TreeFamCLASP2
HOVERGENO75122
HOGENOMO75122
Homologs : HomoloGeneCLASP2
Homology/Alignments : Family Browser (UCSC)CLASP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLASP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLASP2
dbVarCLASP2
ClinVarCLASP2
1000_GenomesCLASP2 
Exome Variant ServerCLASP2
ExAC (Exome Aggregation Consortium)CLASP2 (select the gene name)
Genetic variants : HAPMAP23122
Genomic Variants (DGV)CLASP2 [DGVbeta]
DECIPHERCLASP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLASP2 
Mutations
ICGC Data PortalCLASP2 
TCGA Data PortalCLASP2 
Broad Tumor PortalCLASP2
OASIS PortalCLASP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLASP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLASP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLASP2
DgiDB (Drug Gene Interaction Database)CLASP2
DoCM (Curated mutations)CLASP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLASP2 (select a term)
intoGenCLASP2
Cancer3DCLASP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605853   
Orphanet
MedgenCLASP2
Genetic Testing Registry CLASP2
NextProtO75122 [Medical]
TSGene23122
GENETestsCLASP2
Target ValidationCLASP2
Huge Navigator CLASP2 [HugePedia]
snp3D : Map Gene to Disease23122
BioCentury BCIQCLASP2
ClinGenCLASP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23122
Chemical/Pharm GKB GenePA38435
Clinical trialCLASP2
Miscellaneous
canSAR (ICR)CLASP2 (select the gene name)
Probes
Litterature
PubMed65 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLASP2
EVEXCLASP2
GoPubMedCLASP2
iHOPCLASP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 15:43:44 CEST 2017

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