Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CLCF1 (cardiotrophin-like cytokine factor 1)

Identity

Other namesBSF-3
BSF3
CISS2
CLC
NNT-1
NNT1
NR6
HGNC (Hugo) CLCF1
LocusID (NCBI) 23529
Location 11q13.2
Location_base_pair Starts at 67131639 and ends at 67141648 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)CLCF1   17412
Cards
Entrez_Gene (NCBI)CLCF1  23529  cardiotrophin-like cytokine factor 1
GeneCards (Weizmann)CLCF1
Ensembl (Hinxton)ENSG00000175505 [Gene_View]  chr11:67131639-67141648 [Contig_View]  CLCF1 [Vega]
AceView (NCBI)CLCF1
Genatlas (Paris)CLCF1
WikiGenes23529
SOURCE (Princeton)NM_001166212 NM_013246
Genomic and cartography
GoldenPath (UCSC)CLCF1  -  11q13.2   chr11:67131639-67141648 -  11q13.2   [Description]    (hg19-Feb_2009)
EnsemblCLCF1 - 11q13.2 [CytoView]
Mapping of homologs : NCBICLCF1 [Mapview]
OMIM607672   610313   
Gene and transcription
Genbank (Entrez)AF172854 AF176911 AK298052 AY049779 BC012939
RefSeq transcript (Entrez)NM_001166212 NM_013246
RefSeq genomic (Entrez)AC_000143 NC_000011 NC_018922 NG_013377 NT_167190 NW_001838025 NW_004929380
Consensus coding sequences : CCDS (NCBI)CLCF1
Cluster EST : UnigeneHs.502977 [ NCBI ]
CGAP (NCI)Hs.502977
Alternative Splicing : Fast-db (Paris)GSHG0005940
Alternative Splicing GalleryENSG00000175505
Gene ExpressionCLCF1 [ NCBI-GEO ]     CLCF1 [ SEEK ]   CLCF1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBD9 (Uniprot)
NextProtQ9UBD9  [Medical]
With graphics : InterProQ9UBD9
Splice isoforms : SwissVarQ9UBD9 (Swissvar)
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    PRF   
Related proteins : CluSTrQ9UBD9
Domain families : Pfam (Sanger)PRF (PF06875)   
Domain families : Pfam (NCBI)pfam06875   
DMDM Disease mutations23529
Blocks (Seattle)Q9UBD9
Human Protein AtlasENSG00000175505
Peptide AtlasQ9UBD9
HPRD09643
IPIIPI00294405   IPI00945521   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBD9
IntAct (EBI)Q9UBD9
FunCoupENSG00000175505
BioGRIDCLCF1
InParanoidQ9UBD9
Interologous Interaction database Q9UBD9
IntegromeDBCLCF1
STRING (EMBL)CLCF1
Ontologies - Pathways
Ontology : AmiGOpositive regulation of immunoglobulin production  receptor binding  cytokine activity  cytokine activity  ciliary neurotrophic factor receptor binding  ciliary neurotrophic factor receptor binding  protein binding  extracellular region  extracellular region  cell surface receptor signaling pathway  JAK-STAT cascade  growth factor activity  positive regulation of cell proliferation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of B cell proliferation  positive regulation of tyrosine phosphorylation of Stat3 protein  positive regulation of tyrosine phosphorylation of Stat3 protein  negative regulation of neuron apoptotic process  protein heterodimerization activity  positive regulation of isotype switching to IgE isotypes  positive regulation of astrocyte differentiation  CRLF-CLCF1 complex  CNTFR-CLCF1 complex  
Ontology : EGO-EBIpositive regulation of immunoglobulin production  receptor binding  cytokine activity  cytokine activity  ciliary neurotrophic factor receptor binding  ciliary neurotrophic factor receptor binding  protein binding  extracellular region  extracellular region  cell surface receptor signaling pathway  JAK-STAT cascade  growth factor activity  positive regulation of cell proliferation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of B cell proliferation  positive regulation of tyrosine phosphorylation of Stat3 protein  positive regulation of tyrosine phosphorylation of Stat3 protein  negative regulation of neuron apoptotic process  protein heterodimerization activity  positive regulation of isotype switching to IgE isotypes  positive regulation of astrocyte differentiation  CRLF-CLCF1 complex  CNTFR-CLCF1 complex  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
REACTOMECLCF1
Protein Interaction DatabaseCLCF1
Wikipedia pathwaysCLCF1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)CLCF1
SNP (GeneSNP Utah)CLCF1
SNP : HGBaseCLCF1
Genetic variants : HAPMAPCLCF1
1000_GenomesCLCF1 
ICGC programENSG00000175505 
Somatic Mutations in Cancer : COSMICCLCF1 
CONAN: Copy Number AnalysisCLCF1 
Mutations and Diseases : HGMDCLCF1
OMIM607672    610313   
GENETestsCLCF1
Disease Genetic AssociationCLCF1
Huge Navigator CLCF1 [HugePedia]  CLCF1 [HugeCancerGEM]
Genomic VariantsCLCF1  CLCF1 [DGVbeta]
Exome VariantCLCF1
dbVarCLCF1
ClinVarCLCF1
snp3D : Map Gene to Disease23529
General knowledge
Homologs : HomoloGeneCLCF1
Homology/Alignments : Family Browser (UCSC)CLCF1
Phylogenetic Trees/Animal Genes : TreeFamCLCF1
Chemical/Protein Interactions : CTD23529
Chemical/Pharm GKB GenePA142672106
Clinical trialCLCF1
Cancer Resource (Charite)ENSG00000175505
Other databases
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
CoreMineCLCF1
iHOPCLCF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 17:07:22 CEST 2014

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