Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CLCF1 (cardiotrophin-like cytokine factor 1)

Identity

Other namesBSF-3
BSF3
CISS2
CLC
NNT-1
NNT1
NR6
HGNC (Hugo) CLCF1
LocusID (NCBI) 23529
Atlas_Id 40095
Location 11q13.2
Location_base_pair Starts at 67131639 and ends at 67141648 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLCF1   17412
Cards
Entrez_Gene (NCBI)CLCF1  23529  cardiotrophin-like cytokine factor 1
GeneCards (Weizmann)CLCF1
Ensembl hg19 (Hinxton)ENSG00000175505 [Gene_View]  chr11:67131639-67141648 [Contig_View]  CLCF1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000175505 [Gene_View]  chr11:67131639-67141648 [Contig_View]  CLCF1 [Vega]
ICGC DataPortalENSG00000175505
TCGA cBioPortalCLCF1
AceView (NCBI)CLCF1
Genatlas (Paris)CLCF1
WikiGenes23529
SOURCE (Princeton)CLCF1
Genomic and cartography
GoldenPath hg19 (UCSC)CLCF1  -     chr11:67131639-67141648 -  11q13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CLCF1  -     11q13.2   [Description]    (hg38-Dec_2013)
EnsemblCLCF1 - 11q13.2 [CytoView hg19]  CLCF1 - 11q13.2 [CytoView hg38]
Mapping of homologs : NCBICLCF1 [Mapview hg19]  CLCF1 [Mapview hg38]
OMIM607672   610313   
Gene and transcription
Genbank (Entrez)AF172854 AF176911 AK298052 AY049779 BC012939
RefSeq transcript (Entrez)NM_001166212 NM_013246
RefSeq genomic (Entrez)NC_000011 NC_018922 NG_013377 NT_167190 NW_004929380
Consensus coding sequences : CCDS (NCBI)CLCF1
Cluster EST : UnigeneHs.502977 [ NCBI ]
CGAP (NCI)Hs.502977
Alternative Splicing GalleryENSG00000175505
Gene ExpressionCLCF1 [ NCBI-GEO ]   CLCF1 [ EBI - ARRAY_EXPRESS ]   CLCF1 [ SEEK ]   CLCF1 [ MEM ]
Gene Expression Viewer (FireBrowse)CLCF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23529
GTEX Portal (Tissue expression)CLCF1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UBD9 (Uniprot)
NextProtQ9UBD9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UBD9
Splice isoforms : SwissVarQ9UBD9 (Swissvar)
PhosPhoSitePlusQ9UBD9
Domains : Interpro (EBI)4_helix_cytokine-like_core    4_helix_cytokine_core    PRF   
Domain families : Pfam (Sanger)PRF (PF06875)   
Domain families : Pfam (NCBI)pfam06875   
DMDM Disease mutations23529
Blocks (Seattle)CLCF1
SuperfamilyQ9UBD9
Human Protein AtlasENSG00000175505
Peptide AtlasQ9UBD9
HPRD09643
IPIIPI00294405   IPI00945521   
Protein Interaction databases
DIP (DOE-UCLA)Q9UBD9
IntAct (EBI)Q9UBD9
FunCoupENSG00000175505
BioGRIDCLCF1
STRING (EMBL)CLCF1
ZODIACCLCF1
Ontologies - Pathways
QuickGOQ9UBD9
Ontology : AmiGOpositive regulation of immunoglobulin production  receptor binding  cytokine activity  cytokine activity  ciliary neurotrophic factor receptor binding  ciliary neurotrophic factor receptor binding  protein binding  extracellular region  extracellular region  extracellular region  intracellular  intracellular  cell surface receptor signaling pathway  cell surface receptor signaling pathway  JAK-STAT cascade  growth factor activity  positive regulation of cell proliferation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of B cell proliferation  positive regulation of B cell proliferation  positive regulation of tyrosine phosphorylation of Stat3 protein  positive regulation of tyrosine phosphorylation of Stat3 protein  negative regulation of neuron apoptotic process  protein heterodimerization activity  positive regulation of isotype switching to IgE isotypes  positive regulation of astrocyte differentiation  extracellular exosome  CRLF-CLCF1 complex  CNTFR-CLCF1 complex  
Ontology : EGO-EBIpositive regulation of immunoglobulin production  receptor binding  cytokine activity  cytokine activity  ciliary neurotrophic factor receptor binding  ciliary neurotrophic factor receptor binding  protein binding  extracellular region  extracellular region  extracellular region  intracellular  intracellular  cell surface receptor signaling pathway  cell surface receptor signaling pathway  JAK-STAT cascade  growth factor activity  positive regulation of cell proliferation  cytokine-mediated signaling pathway  B cell differentiation  positive regulation of B cell proliferation  positive regulation of B cell proliferation  positive regulation of tyrosine phosphorylation of Stat3 protein  positive regulation of tyrosine phosphorylation of Stat3 protein  negative regulation of neuron apoptotic process  protein heterodimerization activity  positive regulation of isotype switching to IgE isotypes  positive regulation of astrocyte differentiation  extracellular exosome  CRLF-CLCF1 complex  CNTFR-CLCF1 complex  
Pathways : KEGGCytokine-cytokine receptor interaction    Jak-STAT signaling pathway   
NDEx Network
Atlas of Cancer Signalling NetworkCLCF1
Wikipedia pathwaysCLCF1
Orthology - Evolution
OrthoDB23529
GeneTree (enSembl)ENSG00000175505
Phylogenetic Trees/Animal Genes : TreeFamCLCF1
Homologs : HomoloGeneCLCF1
Homology/Alignments : Family Browser (UCSC)CLCF1
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCLCF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLCF1
dbVarCLCF1
ClinVarCLCF1
1000_GenomesCLCF1 
Exome Variant ServerCLCF1
ExAC (Exome Aggregation Consortium)CLCF1 (select the gene name)
Genetic variants : HAPMAP23529
Genomic Variants (DGV)CLCF1 [DGVbeta]
Mutations
ICGC Data PortalCLCF1 
TCGA Data PortalCLCF1 
Broad Tumor PortalCLCF1
OASIS PortalCLCF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLCF1 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLCF1
DgiDB (Drug Gene Interaction Database)CLCF1
DoCM (Curated mutations)CLCF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLCF1 (select a term)
intoGenCLCF1
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)11:67131639-67141648  ENSG00000175505
CONAN: Copy Number AnalysisCLCF1 
Mutations and Diseases : HGMDCLCF1
OMIM607672    610313   
MedgenCLCF1
Genetic Testing Registry CLCF1
NextProtQ9UBD9 [Medical]
TSGene23529
GENETestsCLCF1
Huge Navigator CLCF1 [HugePedia]
snp3D : Map Gene to Disease23529
BioCentury BCIQCLCF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23529
Chemical/Pharm GKB GenePA142672106
Clinical trialCLCF1
Miscellaneous
canSAR (ICR)CLCF1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLCF1
EVEXCLCF1
GoPubMedCLCF1
iHOPCLCF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 8 18:41:33 CEST 2016

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