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CLCNKA (chloride voltage-gated channel Ka)

Identity

Other namesCLCK1
ClC-K1
hClC-Ka
HGNC (Hugo) CLCNKA
LocusID (NCBI) 1187
Atlas_Id 40098
Location 1p36.13
Location_base_pair Starts at 16348486 and ends at 16360545 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLCNKA   2026
Cards
Entrez_Gene (NCBI)CLCNKA  1187  chloride voltage-gated channel Ka
AliasesCLCK1; ClC-K1; hClC-Ka
GeneCards (Weizmann)CLCNKA
Ensembl hg19 (Hinxton)ENSG00000186510 [Gene_View]  chr1:16348486-16360545 [Contig_View]  CLCNKA [Vega]
Ensembl hg38 (Hinxton)ENSG00000186510 [Gene_View]  chr1:16348486-16360545 [Contig_View]  CLCNKA [Vega]
ICGC DataPortalENSG00000186510
TCGA cBioPortalCLCNKA
AceView (NCBI)CLCNKA
Genatlas (Paris)CLCNKA
WikiGenes1187
SOURCE (Princeton)CLCNKA
Genomic and cartography
GoldenPath hg19 (UCSC)CLCNKA  -     chr1:16348486-16360545 +  1p36.13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CLCNKA  -     1p36.13   [Description]    (hg38-Dec_2013)
EnsemblCLCNKA - 1p36.13 [CytoView hg19]  CLCNKA - 1p36.13 [CytoView hg38]
Mapping of homologs : NCBICLCNKA [Mapview hg19]  CLCNKA [Mapview hg38]
OMIM602024   613090   
Gene and transcription
Genbank (Entrez)AI821546 AK225550 AK290814 AK293476 AK293586
RefSeq transcript (Entrez)NM_001042704 NM_001257139 NM_004070
RefSeq genomic (Entrez)NC_000001 NC_018912 NG_009359 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)CLCNKA
Cluster EST : UnigeneHs.591533 [ NCBI ]
CGAP (NCI)Hs.591533
Alternative Splicing GalleryENSG00000186510
Gene ExpressionCLCNKA [ NCBI-GEO ]   CLCNKA [ EBI - ARRAY_EXPRESS ]   CLCNKA [ SEEK ]   CLCNKA [ MEM ]
Gene Expression Viewer (FireBrowse)CLCNKA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1187
GTEX Portal (Tissue expression)CLCNKA
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51800 (Uniprot)
NextProtP51800  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51800
Splice isoforms : SwissVarP51800 (Swissvar)
PhosPhoSitePlusP51800
Domaine pattern : Prosite (Expaxy)CBS (PS51371)   
Domains : Interpro (EBI)CBS_dom    Cl-channel_core    Cl-channel_volt-gated    Cl_channel-K   
Domain families : Pfam (Sanger)CBS (PF00571)    Voltage_CLC (PF00654)   
Domain families : Pfam (NCBI)pfam00571    pfam00654   
Domain families : Smart (EMBL)CBS (SM00116)  
DMDM Disease mutations1187
Blocks (Seattle)CLCNKA
PDB (SRS)2PFI   
PDB (PDBSum)2PFI   
PDB (IMB)2PFI   
PDB (RSDB)2PFI   
Structural Biology KnowledgeBase2PFI   
SCOP (Structural Classification of Proteins)2PFI   
CATH (Classification of proteins structures)2PFI   
SuperfamilyP51800
Human Protein AtlasENSG00000186510
Peptide AtlasP51800
HPRD03608
IPIIPI00020879   IPI00908815   IPI00641999   
Protein Interaction databases
DIP (DOE-UCLA)P51800
IntAct (EBI)P51800
FunCoupENSG00000186510
BioGRIDCLCNKA
STRING (EMBL)CLCNKA
ZODIACCLCNKA
Ontologies - Pathways
QuickGOP51800
Ontology : AmiGOvoltage-gated chloride channel activity  plasma membrane  integral component of plasma membrane  transport  excretion  ion transmembrane transport  chloride channel complex  metal ion binding  chloride transmembrane transport  regulation of anion transmembrane transport  regulation of anion transmembrane transport  
Ontology : EGO-EBIvoltage-gated chloride channel activity  plasma membrane  integral component of plasma membrane  transport  excretion  ion transmembrane transport  chloride channel complex  metal ion binding  chloride transmembrane transport  regulation of anion transmembrane transport  regulation of anion transmembrane transport  
NDEx Network
Atlas of Cancer Signalling NetworkCLCNKA
Wikipedia pathwaysCLCNKA
Orthology - Evolution
OrthoDB1187
GeneTree (enSembl)ENSG00000186510
Phylogenetic Trees/Animal Genes : TreeFamCLCNKA
Homologs : HomoloGeneCLCNKA
Homology/Alignments : Family Browser (UCSC)CLCNKA
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerCLCNKA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLCNKA
dbVarCLCNKA
ClinVarCLCNKA
1000_GenomesCLCNKA 
Exome Variant ServerCLCNKA
ExAC (Exome Aggregation Consortium)CLCNKA (select the gene name)
Genetic variants : HAPMAP1187
Genomic Variants (DGV)CLCNKA [DGVbeta]
Mutations
ICGC Data PortalCLCNKA 
TCGA Data PortalCLCNKA 
Broad Tumor PortalCLCNKA
OASIS PortalCLCNKA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLCNKA 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLCNKA
DgiDB (Drug Gene Interaction Database)CLCNKA
DoCM (Curated mutations)CLCNKA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLCNKA (select a term)
intoGenCLCNKA
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)1:16348486-16360545  ENSG00000186510
CONAN: Copy Number AnalysisCLCNKA 
Mutations and Diseases : HGMDCLCNKA
OMIM602024    613090   
MedgenCLCNKA
Genetic Testing Registry CLCNKA
NextProtP51800 [Medical]
TSGene1187
GENETestsCLCNKA
Huge Navigator CLCNKA [HugePedia]
snp3D : Map Gene to Disease1187
BioCentury BCIQCLCNKA
ClinGenCLCNKA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1187
Chemical/Pharm GKB GenePA26553
Clinical trialCLCNKA
Miscellaneous
canSAR (ICR)CLCNKA (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLCNKA
EVEXCLCNKA
GoPubMedCLCNKA
iHOPCLCNKA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat May 28 10:58:03 CEST 2016

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