Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CLCNKB (chloride voltage-gated channel Kb)

Identity

Alias_nameschloride channel Kb
chloride channel, voltage-sensitive Kb
Alias_symbol (synonym)hClC-Kb
Other aliasCLCKB
ClC-K2
ClC-Kb
HGNC (Hugo) CLCNKB
LocusID (NCBI) 1188
Atlas_Id 61855
Location 1p36.13  [Link to chromosome band 1p36]
Location_base_pair Starts at 16043736 and ends at 16057326 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CLCNKB (1p36.13) / ABHD2 (15q26.1)TNKS2 (10q23.32) / CLCNKB (1p36.13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLCNKB   2027
Cards
Entrez_Gene (NCBI)CLCNKB  1188  chloride voltage-gated channel Kb
AliasesCLCKB; ClC-K2; ClC-Kb
GeneCards (Weizmann)CLCNKB
Ensembl hg19 (Hinxton)ENSG00000184908 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184908 [Gene_View]  chr1:16043736-16057326 [Contig_View]  CLCNKB [Vega]
ICGC DataPortalENSG00000184908
TCGA cBioPortalCLCNKB
AceView (NCBI)CLCNKB
Genatlas (Paris)CLCNKB
WikiGenes1188
SOURCE (Princeton)CLCNKB
Genetics Home Reference (NIH)CLCNKB
Genomic and cartography
GoldenPath hg38 (UCSC)CLCNKB  -     chr1:16043736-16057326 +  1p36.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLCNKB  -     1p36.13   [Description]    (hg19-Feb_2009)
EnsemblCLCNKB - 1p36.13 [CytoView hg19]  CLCNKB - 1p36.13 [CytoView hg38]
Mapping of homologs : NCBICLCNKB [Mapview hg19]  CLCNKB [Mapview hg38]
OMIM602023   607364   613090   
Gene and transcription
Genbank (Entrez)AK098217 AK292335 BC020873 BC033806 BC109243
RefSeq transcript (Entrez)NM_000085 NM_001165945
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLCNKB
Cluster EST : UnigeneHs.352243 [ NCBI ]
CGAP (NCI)Hs.352243
Alternative Splicing GalleryENSG00000184908
Gene ExpressionCLCNKB [ NCBI-GEO ]   CLCNKB [ EBI - ARRAY_EXPRESS ]   CLCNKB [ SEEK ]   CLCNKB [ MEM ]
Gene Expression Viewer (FireBrowse)CLCNKB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1188
GTEX Portal (Tissue expression)CLCNKB
Protein : pattern, domain, 3D structure
UniProt/SwissProtP51801   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP51801  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP51801
Splice isoforms : SwissVarP51801
PhosPhoSitePlusP51801
Domaine pattern : Prosite (Expaxy)CBS (PS51371)   
Domains : Interpro (EBI)CBS_dom    Cl-channel_core    Cl-channel_volt-gated    Cl_channel-K   
Domain families : Pfam (Sanger)CBS (PF00571)    Voltage_CLC (PF00654)   
Domain families : Pfam (NCBI)pfam00571    pfam00654   
Domain families : Smart (EMBL)CBS (SM00116)  
Conserved Domain (NCBI)CLCNKB
DMDM Disease iutatko~s1188
Blocks (Seattle)CLCNKB
SuperfamilyP51801
Human Protein AtlasENSG00000184908
Peptide AtlasP51801
HPRD03607
IPIIPI00020881   IPI00844478   IPI00514076   IPI00946376   IPI00641080   
Protein Interaction databases
DIP (DOE-UCLA)P51801
IntAct (EBI)P51801
FunCoupENSG00000184908
BioGRIDCLCNKB
STRING (EMBL)CLCNKB
ZODIACCLCNKB
Ontologies - Pathways
QuickGOP51801
Ontology : AmiGOvoltage-gated chloride channel activity  voltage-gated chloride channel activity  plasma membrane  integral component of plasma membrane  transport  excretion  ion transmembrane transport  chloride channel complex  metal ion binding  chloride transmembrane transport  regulation of anion transmembrane transport  
Ontology : EGO-EBIvoltage-gated chloride channel activity  voltage-gated chloride channel activity  plasma membrane  integral component of plasma membrane  transport  excretion  ion transmembrane transport  chloride channel complex  metal ion binding  chloride transmembrane transport  regulation of anion transmembrane transport  
Pathways : KEGGColde#ting duct acid secretion   
NDEx NetworkCLCNKB
Atlas of Cancer Signalling NetworkCLCNKB
Wikipedia pathwaysCLCNKB
Orthology - Evolution
OrthoDB1188
GeneTree (enSembl)ENSG00000184908
Phylogenetic Trees/Animal Genes : TreeFamCLCNKB
HOVERGENP51801
HOGENOMP51801
Homologs : HomoloGeneCLCNKB
Homology/Alignments : Family Browser (UCSC)CLCNKB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLCNKB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLCNKB
dbVarCLCNKB
ClinVarCLCNKB
1000_GenomesCLCNKB 
Exome Variant ServerCLCNKB
ExAC (Exome Aggregation Consortium)CLCNKB (select the gene name)
Genetic variants : HAPMAP1188
Genomic Variants (DGV)CLCNKB [DGVbeta]
DECIPHERCLCNKB [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLCNKB 
Mutations
ICGC Data PortalCLCNKB 
TCGA Data PortalCLCNKB 
Broad Tumor PortalCLCNKB
OASIS PortalCLCNKB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLCNKB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLCNKB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
BioMutasearch CLCNKB
DgiDB (Drug Gene Interaction Database)CLCNKB
DoCM (Curated mutations)CLCNKB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLCNKB (select a term)
intoGenCLCNKB
Cancer3DCLCNKB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602023    607364    613090   
Orphanet1045    11913    12438   
MedgenCLCNKB
Genetic Testing Registry CLCNKB
NextProtP51801 [Medical]
TSGene1188
GENETestsCLCNKB
Target ValidationCLCNKB
Huge Navigator CLCNKB [HugePedia]
snp3D : Map Gene to Disease1188
BioCentury BCIQCLCNKB
ClinGenCLCNKB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1188
Chemical/Pharm GKB GenePA26554
Clinical trialCLCNKB
Miscellaneous
canSAR (ICR)CLCNKB (select the gene name)
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLCNKB
EVEXCLCNKB
GoPubMedCLCNKB
iHOPCLCNKB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:04:53 CEST 2017

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