Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CLDN11 (claudin 11)

Identity

Alias_namesOTM
oligodendrocyte transmembrane protein
Alias_symbol (synonym)OSP
Other alias
HGNC (Hugo) CLDN11
LocusID (NCBI) 5010
Atlas_Id 51464
Location 3q26.2  [Link to chromosome band 3q26]
Location_base_pair Starts at 170421240 and ends at 170434691 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CLDN11 (3q26.2) / AASDHPPT (11q22.3)CLDN11 (3q26.2) / KCNMB4 (12q15)CLDN11 (3q26.2) / NCAM2 (21q21.1)
CLDN11 (3q26.2) / TSTD2 (9q22.33)CMTM7 (3p22.3) / CLDN11 (3q26.2)CMTM7 3p22.3 / CLDN11 3q26.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLDN11   8514
Cards
Entrez_Gene (NCBI)CLDN11  5010  claudin 11
AliasesOSP; OTM
GeneCards (Weizmann)CLDN11
Ensembl hg19 (Hinxton)ENSG00000013297 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000013297 [Gene_View]  chr3:170421240-170434691 [Contig_View]  CLDN11 [Vega]
ICGC DataPortalENSG00000013297
TCGA cBioPortalCLDN11
AceView (NCBI)CLDN11
Genatlas (Paris)CLDN11
WikiGenes5010
SOURCE (Princeton)CLDN11
Genetics Home Reference (NIH)CLDN11
Genomic and cartography
GoldenPath hg38 (UCSC)CLDN11  -     chr3:170421240-170434691 +  3q26.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLDN11  -     3q26.2   [Description]    (hg19-Feb_2009)
EnsemblCLDN11 - 3q26.2 [CytoView hg19]  CLDN11 - 3q26.2 [CytoView hg38]
Mapping of homologs : NCBICLDN11 [Mapview hg19]  CLDN11 [Mapview hg38]
OMIM601326   
Gene and transcription
Genbank (Entrez)AF085871 AJ245901 AJ245902 AK098766 AK294087
RefSeq transcript (Entrez)NM_001185056 NM_005602
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLDN11
Cluster EST : UnigeneHs.31595 [ NCBI ]
CGAP (NCI)Hs.31595
Alternative Splicing GalleryENSG00000013297
Gene ExpressionCLDN11 [ NCBI-GEO ]   CLDN11 [ EBI - ARRAY_EXPRESS ]   CLDN11 [ SEEK ]   CLDN11 [ MEM ]
Gene Expression Viewer (FireBrowse)CLDN11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)5010
GTEX Portal (Tissue expression)CLDN11
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75508   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75508  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75508
Splice isoforms : SwissVarO75508
PhosPhoSitePlusO75508
Domaine pattern : Prosite (Expaxy)CLAUDIN (PS01346)   
Domains : Interpro (EBI)Claudin    Claudin11    Claudin_CS    PMP22/EMP/MP20/Claudin   
Domain families : Pfam (Sanger)PMP22_Claudin (PF00822)   
Domain families : Pfam (NCBI)pfam00822   
Conserved Domain (NCBI)CLDN11
DMDM Disease mutations5010
Blocks (Seattle)CLDN11
SuperfamilyO75508
Human Protein AtlasENSG00000013297
Peptide AtlasO75508
HPRD03207
IPIIPI00026053   IPI00981494   IPI00909146   
Protein Interaction databases
DIP (DOE-UCLA)O75508
IntAct (EBI)O75508
FunCoupENSG00000013297
BioGRIDCLDN11
STRING (EMBL)CLDN11
ZODIACCLDN11
Ontologies - Pathways
QuickGOO75508
Ontology : AmiGOstructural molecule activity  protein binding  plasma membrane  bicellular tight junction  spermatogenesis  axon ensheathment  integral component of membrane  calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  identical protein binding  myelin sheath  basal part of cell  extracellular exosome  
Ontology : EGO-EBIstructural molecule activity  protein binding  plasma membrane  bicellular tight junction  spermatogenesis  axon ensheathment  integral component of membrane  calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  identical protein binding  myelin sheath  basal part of cell  extracellular exosome  
Pathways : KEGGCell adhesion molecules (CAMs)    Tight junction    Leukocyte transendothelial migration    Hepatitis C   
NDEx NetworkCLDN11
Atlas of Cancer Signalling NetworkCLDN11
Wikipedia pathwaysCLDN11
Orthology - Evolution
OrthoDB5010
GeneTree (enSembl)ENSG00000013297
Phylogenetic Trees/Animal Genes : TreeFamCLDN11
HOVERGENO75508
HOGENOMO75508
Homologs : HomoloGeneCLDN11
Homology/Alignments : Family Browser (UCSC)CLDN11
Gene fusions - Rearrangements
Fusion : MitelmanCMTM7/CLDN11 [3p22.3/3q26.2]  [t(3;3)(p22;q26)]  
Fusion: TCGACMTM7 3p22.3 CLDN11 3q26.2 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLDN11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLDN11
dbVarCLDN11
ClinVarCLDN11
1000_GenomesCLDN11 
Exome Variant ServerCLDN11
ExAC (Exome Aggregation Consortium)CLDN11 (select the gene name)
Genetic variants : HAPMAP5010
Genomic Variants (DGV)CLDN11 [DGVbeta]
DECIPHERCLDN11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLDN11 
Mutations
ICGC Data PortalCLDN11 
TCGA Data PortalCLDN11 
Broad Tumor PortalCLDN11
OASIS PortalCLDN11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLDN11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLDN11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLDN11
DgiDB (Drug Gene Interaction Database)CLDN11
DoCM (Curated mutations)CLDN11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLDN11 (select a term)
intoGenCLDN11
Cancer3DCLDN11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601326   
Orphanet
MedgenCLDN11
Genetic Testing Registry CLDN11
NextProtO75508 [Medical]
TSGene5010
GENETestsCLDN11
Target ValidationCLDN11
Huge Navigator CLDN11 [HugePedia]
snp3D : Map Gene to Disease5010
BioCentury BCIQCLDN11
ClinGenCLDN11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD5010
Chemical/Pharm GKB GenePA26559
Clinical trialCLDN11
Miscellaneous
canSAR (ICR)CLDN11 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLDN11
EVEXCLDN11
GoPubMedCLDN11
iHOPCLDN11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:02:40 CEST 2017

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