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CLDN12 (claudin 12)

Identity

Other alias-
HGNC (Hugo) CLDN12
LocusID (NCBI) 9069
Atlas_Id 49800
Location 7q21.13  [Link to chromosome band 7q21]
Location_base_pair Starts at 90403334 and ends at 90415954 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CLDN12 (7q21.13) / SPCS3 (4q34.2)CLDN12 7q21.13 / SPCS3 4q34.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLDN12   2034
Cards
Entrez_Gene (NCBI)CLDN12  9069  claudin 12
Aliases
GeneCards (Weizmann)CLDN12
Ensembl hg19 (Hinxton)ENSG00000157224 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157224 [Gene_View]  chr7:90403334-90415954 [Contig_View]  CLDN12 [Vega]
ICGC DataPortalENSG00000157224
TCGA cBioPortalCLDN12
AceView (NCBI)CLDN12
Genatlas (Paris)CLDN12
WikiGenes9069
SOURCE (Princeton)CLDN12
Genetics Home Reference (NIH)CLDN12
Genomic and cartography
GoldenPath hg38 (UCSC)CLDN12  -     chr7:90403334-90415954 +  7q21.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLDN12  -     7q21.13   [Description]    (hg19-Feb_2009)
EnsemblCLDN12 - 7q21.13 [CytoView hg19]  CLDN12 - 7q21.13 [CytoView hg38]
Mapping of homologs : NCBICLDN12 [Mapview hg19]  CLDN12 [Mapview hg38]
OMIM611232   
Gene and transcription
Genbank (Entrez)AK312480 AL136770 AM392715 BC036754 BC068532
RefSeq transcript (Entrez)NM_001185072 NM_001185073 NM_012129
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLDN12
Cluster EST : UnigeneHs.731917 [ NCBI ]
CGAP (NCI)Hs.731917
Alternative Splicing GalleryENSG00000157224
Gene ExpressionCLDN12 [ NCBI-GEO ]   CLDN12 [ EBI - ARRAY_EXPRESS ]   CLDN12 [ SEEK ]   CLDN12 [ MEM ]
Gene Expression Viewer (FireBrowse)CLDN12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9069
GTEX Portal (Tissue expression)CLDN12
Protein : pattern, domain, 3D structure
UniProt/SwissProtP56749   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP56749  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP56749
Splice isoforms : SwissVarP56749
PhosPhoSitePlusP56749
Domaine pattern : Prosite (Expaxy)CLAUDIN (PS01346)   
Domains : Interpro (EBI)Claudin12    Claudin_CS   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CLDN12
DMDM Disease mutations9069
Blocks (Seattle)CLDN12
SuperfamilyP56749
Human Protein AtlasENSG00000157224
Peptide AtlasP56749
HPRD13064
IPIIPI00011088   IPI00658065   IPI00657942   IPI00879499   
Protein Interaction databases
DIP (DOE-UCLA)P56749
IntAct (EBI)P56749
FunCoupENSG00000157224
BioGRIDCLDN12
STRING (EMBL)CLDN12
ZODIACCLDN12
Ontologies - Pathways
QuickGOP56749
Ontology : AmiGOstructural molecule activity  protein binding  plasma membrane  bicellular tight junction  integral component of membrane  lateral plasma membrane  calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  identical protein binding  
Ontology : EGO-EBIstructural molecule activity  protein binding  plasma membrane  bicellular tight junction  integral component of membrane  lateral plasma membrane  calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  identical protein binding  
NDEx NetworkCLDN12
Atlas of Cancer Signalling NetworkCLDN12
Wikipedia pathwaysCLDN12
Orthology - Evolution
OrthoDB9069
GeneTree (enSembl)ENSG00000157224
Phylogenetic Trees/Animal Genes : TreeFamCLDN12
HOVERGENP56749
HOGENOMP56749
Homologs : HomoloGeneCLDN12
Homology/Alignments : Family Browser (UCSC)CLDN12
Gene fusions - Rearrangements
Fusion : MitelmanCLDN12/SPCS3 [7q21.13/4q34.2]  
Fusion: TCGACLDN12 7q21.13 SPCS3 4q34.2 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLDN12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLDN12
dbVarCLDN12
ClinVarCLDN12
1000_GenomesCLDN12 
Exome Variant ServerCLDN12
ExAC (Exome Aggregation Consortium)CLDN12 (select the gene name)
Genetic variants : HAPMAP9069
Genomic Variants (DGV)CLDN12 [DGVbeta]
DECIPHERCLDN12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLDN12 
Mutations
ICGC Data PortalCLDN12 
TCGA Data PortalCLDN12 
Broad Tumor PortalCLDN12
OASIS PortalCLDN12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLDN12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLDN12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLDN12
DgiDB (Drug Gene Interaction Database)CLDN12
DoCM (Curated mutations)CLDN12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLDN12 (select a term)
intoGenCLDN12
Cancer3DCLDN12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611232   
Orphanet
MedgenCLDN12
Genetic Testing Registry CLDN12
NextProtP56749 [Medical]
TSGene9069
GENETestsCLDN12
Target ValidationCLDN12
Huge Navigator CLDN12 [HugePedia]
snp3D : Map Gene to Disease9069
BioCentury BCIQCLDN12
ClinGenCLDN12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9069
Chemical/Pharm GKB GenePA26560
Clinical trialCLDN12
Miscellaneous
canSAR (ICR)CLDN12 (select the gene name)
Probes
Litterature
PubMed32 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLDN12
EVEXCLDN12
GoPubMedCLDN12
iHOPCLDN12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:02:40 CEST 2017

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