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CLDN14 (claudin 14)

Identity

Alias (NCBI)DFNB29
HGNC (Hugo) CLDN14
HGNC Previous nameDFNB29
LocusID (NCBI) 23562
Atlas_Id 54074
Location 21q22.13  [Link to chromosome band 21q22]
Location_base_pair Starts at 36460621 and ends at 36480122 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MAST2 (1p34.1) / CLDN14 (21q22.13)MAST2 1p34.1 / CLDN14 21q22.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

 

Nomenclature
HGNC (Hugo)CLDN14   2035
Cards
Entrez_Gene (NCBI)CLDN14    claudin 14
AliasesDFNB29
GeneCards (Weizmann)CLDN14
Ensembl hg19 (Hinxton)ENSG00000159261 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159261 [Gene_View]  ENSG00000159261 [Sequence]  chr21:36460621-36480122 [Contig_View]  CLDN14 [Vega]
ICGC DataPortalENSG00000159261
TCGA cBioPortalCLDN14
AceView (NCBI)CLDN14
Genatlas (Paris)CLDN14
SOURCE (Princeton)CLDN14
Genetics Home Reference (NIH)CLDN14
Genomic and cartography
GoldenPath hg38 (UCSC)CLDN14  -     chr21:36460621-36480122 -  21q22.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLDN14  -     21q22.13   [Description]    (hg19-Feb_2009)
GoldenPathCLDN14 - 21q22.13 [CytoView hg19]  CLDN14 - 21q22.13 [CytoView hg38]
ImmunoBaseENSG00000159261
Genome Data Viewer NCBICLDN14 [Mapview hg19]  
OMIM605608   614035   
Gene and transcription
Genbank (Entrez)AF314090 AI655909 AJ566765 AJ566766 AY355348
RefSeq transcript (Entrez)NM_001146077 NM_001146078 NM_001146079 NM_012130 NM_144492
Consensus coding sequences : CCDS (NCBI)CLDN14
Gene ExpressionCLDN14 [ NCBI-GEO ]   CLDN14 [ EBI - ARRAY_EXPRESS ]   CLDN14 [ SEEK ]   CLDN14 [ MEM ]
Gene Expression Viewer (FireBrowse)CLDN14 [ Firebrowse - Broad ]
GenevisibleExpression of CLDN14 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23562
GTEX Portal (Tissue expression)CLDN14
Human Protein AtlasENSG00000159261-CLDN14 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95500   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95500  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95500
PhosPhoSitePlusO95500
Domaine pattern : Prosite (Expaxy)CLAUDIN (PS01346)   
Domains : Interpro (EBI)Claudin    Claudin14    Claudin_CS    PMP22/EMP/MP20/Claudin   
Domain families : Pfam (Sanger)PMP22_Claudin (PF00822)   
Domain families : Pfam (NCBI)pfam00822   
Conserved Domain (NCBI)CLDN14
SuperfamilyO95500
AlphaFold pdb e-kbO95500   
Human Protein Atlas [tissue]ENSG00000159261-CLDN14 [tissue]
HPRD05727
Protein Interaction databases
DIP (DOE-UCLA)O95500
IntAct (EBI)O95500
BioGRIDCLDN14
STRING (EMBL)CLDN14
ZODIACCLDN14
Ontologies - Pathways
QuickGOO95500
Ontology : AmiGOstructural molecule activity  protein binding  endoplasmic reticulum  plasma membrane  plasma membrane  bicellular tight junction  bicellular tight junction  cell adhesion  integral component of membrane  calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  identical protein binding  protein-containing complex assembly  bicellular tight junction assembly  
Ontology : EGO-EBIstructural molecule activity  protein binding  endoplasmic reticulum  plasma membrane  plasma membrane  bicellular tight junction  bicellular tight junction  cell adhesion  integral component of membrane  calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  identical protein binding  protein-containing complex assembly  bicellular tight junction assembly  
Pathways : KEGGCell adhesion molecules (CAMs)    Tight junction    Leukocyte transendothelial migration    Hepatitis C   
NDEx NetworkCLDN14
Atlas of Cancer Signalling NetworkCLDN14
Wikipedia pathwaysCLDN14
Orthology - Evolution
OrthoDB23562
GeneTree (enSembl)ENSG00000159261
Phylogenetic Trees/Animal Genes : TreeFamCLDN14
Homologs : HomoloGeneCLDN14
Homology/Alignments : Family Browser (UCSC)CLDN14
Gene fusions - Rearrangements
Fusion : MitelmanMAST2/CLDN14 [1p34.1/21q22.13]  
Fusion : QuiverCLDN14
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLDN14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLDN14
dbVarCLDN14
ClinVarCLDN14
MonarchCLDN14
1000_GenomesCLDN14 
Exome Variant ServerCLDN14
GNOMAD BrowserENSG00000159261
Varsome BrowserCLDN14
ACMGCLDN14 variants
VarityO95500
Genomic Variants (DGV)CLDN14 [DGVbeta]
DECIPHERCLDN14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLDN14 
Mutations
ICGC Data PortalCLDN14 
TCGA Data PortalCLDN14 
Broad Tumor PortalCLDN14
OASIS PortalCLDN14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLDN14  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCLDN14
Mutations and Diseases : HGMDCLDN14
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCLDN14
DgiDB (Drug Gene Interaction Database)CLDN14
DoCM (Curated mutations)CLDN14
CIViC (Clinical Interpretations of Variants in Cancer)CLDN14
Cancer3DCLDN14
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605608    614035   
Orphanet12047   
DisGeNETCLDN14
MedgenCLDN14
Genetic Testing Registry CLDN14
NextProtO95500 [Medical]
GENETestsCLDN14
Target ValidationCLDN14
Huge Navigator CLDN14 [HugePedia]
ClinGenCLDN14
Clinical trials, drugs, therapy
MyCancerGenomeCLDN14
Protein Interactions : CTDCLDN14
Pharm GKB GenePA26561
PharosO95500
Clinical trialCLDN14
Miscellaneous
canSAR (ICR)CLDN14
HarmonizomeCLDN14
DataMed IndexCLDN14
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCLDN14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:04:13 CEST 2021
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