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CLDN14 (claudin 14)

Identity

Alias_namesDFNB29
Other alias
HGNC (Hugo) CLDN14
LocusID (NCBI) 23562
Atlas_Id 54074
Location 21q22.13  [Link to chromosome band 21q22]
Location_base_pair Starts at 36460621 and ends at 36576569 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MAST2 (1p34.1) / CLDN14 (21q22.13)MAST2 1p34.1 / CLDN14 21q22.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLDN14   2035
Cards
Entrez_Gene (NCBI)CLDN14  23562  claudin 14
AliasesDFNB29
GeneCards (Weizmann)CLDN14
Ensembl hg19 (Hinxton)ENSG00000159261 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159261 [Gene_View]  chr21:36460621-36576569 [Contig_View]  CLDN14 [Vega]
ICGC DataPortalENSG00000159261
TCGA cBioPortalCLDN14
AceView (NCBI)CLDN14
Genatlas (Paris)CLDN14
WikiGenes23562
SOURCE (Princeton)CLDN14
Genetics Home Reference (NIH)CLDN14
Genomic and cartography
GoldenPath hg38 (UCSC)CLDN14  -     chr21:36460621-36576569 -  21q22.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLDN14  -     21q22.13   [Description]    (hg19-Feb_2009)
EnsemblCLDN14 - 21q22.13 [CytoView hg19]  CLDN14 - 21q22.13 [CytoView hg38]
Mapping of homologs : NCBICLDN14 [Mapview hg19]  CLDN14 [Mapview hg38]
OMIM605608   614035   
Gene and transcription
Genbank (Entrez)AF314090 AI655909 AJ566765 AJ566766 AY355348
RefSeq transcript (Entrez)NM_001146077 NM_001146078 NM_001146079 NM_012130 NM_144492
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLDN14
Cluster EST : UnigeneHs.741857 [ NCBI ]
CGAP (NCI)Hs.741857
Alternative Splicing GalleryENSG00000159261
Gene ExpressionCLDN14 [ NCBI-GEO ]   CLDN14 [ EBI - ARRAY_EXPRESS ]   CLDN14 [ SEEK ]   CLDN14 [ MEM ]
Gene Expression Viewer (FireBrowse)CLDN14 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23562
GTEX Portal (Tissue expression)CLDN14
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95500   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95500  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95500
Splice isoforms : SwissVarO95500
PhosPhoSitePlusO95500
Domaine pattern : Prosite (Expaxy)CLAUDIN (PS01346)   
Domains : Interpro (EBI)Claudin    Claudin14    Claudin_CS    PMP22/EMP/MP20/Claudin   
Domain families : Pfam (Sanger)PMP22_Claudin (PF00822)   
Domain families : Pfam (NCBI)pfam00822   
Conserved Domain (NCBI)CLDN14
DMDM Disease mutations23562
Blocks (Seattle)CLDN14
SuperfamilyO95500
Human Protein AtlasENSG00000159261
Peptide AtlasO95500
HPRD05727
IPIIPI00031288   
Protein Interaction databases
DIP (DOE-UCLA)O95500
IntAct (EBI)O95500
FunCoupENSG00000159261
BioGRIDCLDN14
STRING (EMBL)CLDN14
ZODIACCLDN14
Ontologies - Pathways
QuickGOO95500
Ontology : AmiGOstructural molecule activity  endoplasmic reticulum  plasma membrane  bicellular tight junction  protein complex assembly  integral component of membrane  calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  identical protein binding  
Ontology : EGO-EBIstructural molecule activity  endoplasmic reticulum  plasma membrane  bicellular tight junction  protein complex assembly  integral component of membrane  calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules  identical protein binding  
Pathways : KEGGCell adhesion molecules (CAMs)    Tight junction    Leukocyte transendothelial migration    Hepatitis C   
NDEx NetworkCLDN14
Atlas of Cancer Signalling NetworkCLDN14
Wikipedia pathwaysCLDN14
Orthology - Evolution
OrthoDB23562
GeneTree (enSembl)ENSG00000159261
Phylogenetic Trees/Animal Genes : TreeFamCLDN14
HOVERGENO95500
HOGENOMO95500
Homologs : HomoloGeneCLDN14
Homology/Alignments : Family Browser (UCSC)CLDN14
Gene fusions - Rearrangements
Fusion : MitelmanMAST2/CLDN14 [1p34.1/21q22.13]  [t(1;21)(p34;q22)]  
Fusion: TCGAMAST2 1p34.1 CLDN14 21q22.13 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLDN14 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLDN14
dbVarCLDN14
ClinVarCLDN14
1000_GenomesCLDN14 
Exome Variant ServerCLDN14
ExAC (Exome Aggregation Consortium)CLDN14 (select the gene name)
Genetic variants : HAPMAP23562
Genomic Variants (DGV)CLDN14 [DGVbeta]
DECIPHERCLDN14 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLDN14 
Mutations
ICGC Data PortalCLDN14 
TCGA Data PortalCLDN14 
Broad Tumor PortalCLDN14
OASIS PortalCLDN14 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLDN14  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLDN14
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch CLDN14
DgiDB (Drug Gene Interaction Database)CLDN14
DoCM (Curated mutations)CLDN14 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLDN14 (select a term)
intoGenCLDN14
Cancer3DCLDN14(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605608    614035   
Orphanet12047   
MedgenCLDN14
Genetic Testing Registry CLDN14
NextProtO95500 [Medical]
TSGene23562
GENETestsCLDN14
Target ValidationCLDN14
Huge Navigator CLDN14 [HugePedia]
snp3D : Map Gene to Disease23562
BioCentury BCIQCLDN14
ClinGenCLDN14
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23562
Chemical/Pharm GKB GenePA26561
Clinical trialCLDN14
Miscellaneous
canSAR (ICR)CLDN14 (select the gene name)
Probes
Litterature
PubMed34 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLDN14
EVEXCLDN14
GoPubMedCLDN14
iHOPCLDN14
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:02:41 CEST 2017

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