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CLEC12A (C-type lectin domain family 12 member A)

Identity

Alias_namesC-type lectin domain family 12
Alias_symbol (synonym)CLL-1
MICL
CD371
DCAL-2
Other aliasCLL1
HGNC (Hugo) CLEC12A
LocusID (NCBI) 160364
Atlas_Id 49855
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 9951316 and ends at 9985595 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLEC12A   31713
Cards
Entrez_Gene (NCBI)CLEC12A  160364  C-type lectin domain family 12 member A
AliasesCD371; CLL-1; CLL1; DCAL-2; 
MICL
GeneCards (Weizmann)CLEC12A
Ensembl hg19 (Hinxton)ENSG00000172322 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172322 [Gene_View]  chr12:9951316-9985595 [Contig_View]  CLEC12A [Vega]
ICGC DataPortalENSG00000172322
TCGA cBioPortalCLEC12A
AceView (NCBI)CLEC12A
Genatlas (Paris)CLEC12A
WikiGenes160364
SOURCE (Princeton)CLEC12A
Genetics Home Reference (NIH)CLEC12A
Genomic and cartography
GoldenPath hg38 (UCSC)CLEC12A  -     chr12:9951316-9985595 +  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLEC12A  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblCLEC12A - 12p13.31 [CytoView hg19]  CLEC12A - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBICLEC12A [Mapview hg19]  CLEC12A [Mapview hg38]
OMIM612088   
Gene and transcription
Genbank (Entrez)AF247788 AK314001 AY426759 AY498550 AY498551
RefSeq transcript (Entrez)NM_001207010 NM_001300730 NM_138337 NM_201623 NM_201625
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLEC12A
Cluster EST : UnigeneHs.190519 [ NCBI ]
CGAP (NCI)Hs.190519
Alternative Splicing GalleryENSG00000172322
Gene ExpressionCLEC12A [ NCBI-GEO ]   CLEC12A [ EBI - ARRAY_EXPRESS ]   CLEC12A [ SEEK ]   CLEC12A [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC12A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)160364
GTEX Portal (Tissue expression)CLEC12A
Human Protein AtlasENSG00000172322-CLEC12A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5QGZ9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5QGZ9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5QGZ9
Splice isoforms : SwissVarQ5QGZ9
PhosPhoSitePlusQ5QGZ9
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    CTDL_fold    NKR-like_CTLD   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)CLEC12A
DMDM Disease mutations160364
Blocks (Seattle)CLEC12A
SuperfamilyQ5QGZ9
Human Protein Atlas [tissue]ENSG00000172322-CLEC12A [tissue]
Peptide AtlasQ5QGZ9
HPRD14719
IPIIPI00880140   IPI00747901   IPI00401794   IPI00401793   IPI00879754   IPI01009716   IPI00873847   IPI01013808   
Protein Interaction databases
DIP (DOE-UCLA)Q5QGZ9
IntAct (EBI)Q5QGZ9
FunCoupENSG00000172322
BioGRIDCLEC12A
STRING (EMBL)CLEC12A
ZODIACCLEC12A
Ontologies - Pathways
QuickGOQ5QGZ9
Ontology : AmiGOplasma membrane  integral component of membrane  carbohydrate binding  specific granule membrane  neutrophil degranulation  tertiary granule membrane  
Ontology : EGO-EBIplasma membrane  integral component of membrane  carbohydrate binding  specific granule membrane  neutrophil degranulation  tertiary granule membrane  
NDEx NetworkCLEC12A
Atlas of Cancer Signalling NetworkCLEC12A
Wikipedia pathwaysCLEC12A
Orthology - Evolution
OrthoDB160364
GeneTree (enSembl)ENSG00000172322
Phylogenetic Trees/Animal Genes : TreeFamCLEC12A
HOVERGENQ5QGZ9
HOGENOMQ5QGZ9
Homologs : HomoloGeneCLEC12A
Homology/Alignments : Family Browser (UCSC)CLEC12A
Gene fusions - Rearrangements
Tumor Fusion PortalCLEC12A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC12A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC12A
dbVarCLEC12A
ClinVarCLEC12A
1000_GenomesCLEC12A 
Exome Variant ServerCLEC12A
ExAC (Exome Aggregation Consortium)ENSG00000172322
GNOMAD BrowserENSG00000172322
Genetic variants : HAPMAP160364
Genomic Variants (DGV)CLEC12A [DGVbeta]
DECIPHERCLEC12A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLEC12A 
Mutations
ICGC Data PortalCLEC12A 
TCGA Data PortalCLEC12A 
Broad Tumor PortalCLEC12A
OASIS PortalCLEC12A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC12A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLEC12A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLEC12A
DgiDB (Drug Gene Interaction Database)CLEC12A
DoCM (Curated mutations)CLEC12A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC12A (select a term)
intoGenCLEC12A
Cancer3DCLEC12A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612088   
Orphanet
DisGeNETCLEC12A
MedgenCLEC12A
Genetic Testing Registry CLEC12A
NextProtQ5QGZ9 [Medical]
TSGene160364
GENETestsCLEC12A
Target ValidationCLEC12A
Huge Navigator CLEC12A [HugePedia]
snp3D : Map Gene to Disease160364
BioCentury BCIQCLEC12A
ClinGenCLEC12A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD160364
Chemical/Pharm GKB GenePA142672094
Clinical trialCLEC12A
Miscellaneous
canSAR (ICR)CLEC12A (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC12A
EVEXCLEC12A
GoPubMedCLEC12A
iHOPCLEC12A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:08:03 CET 2017

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