Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 160364
MIM: 612088
HGNC: 31713
Ensembl: ENSG00000172322
Variants:
dbSNP: 160364
ClinVar: 160364
TCGA: ENSG00000172322
COSMIC: CLEC12A
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Innate Immune System | REACTOME | R-HSA-168249 |
| Neutrophil degranulation | REACTOME | R-HSA-6798695 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38367667 | 2024 | Mechanistic insights into the C-type lectin receptor CLEC12A-mediated immune recognition of monosodium urate crystal. | 0 |
| 38386511 | 2024 | Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. | 0 |
| 38367667 | 2024 | Mechanistic insights into the C-type lectin receptor CLEC12A-mediated immune recognition of monosodium urate crystal. | 0 |
| 38386511 | 2024 | Crystal structure of the complex of CLEC12A and an antibody that interferes with binding of diverse ligands. | 0 |
| 36542980 | 2023 | Mycobacterial mycolic acids trigger inhibitory receptor Clec12A to suppress host immune responses. | 3 |
| 36928077 | 2023 | Identification of two early blood biomarkers ACHE and CLEC12A for improved risk stratification of critically ill COVID-19 patients. | 1 |
| 37102643 | 2023 | Behçet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions. | 1 |
| 36542980 | 2023 | Mycobacterial mycolic acids trigger inhibitory receptor Clec12A to suppress host immune responses. | 3 |
| 36928077 | 2023 | Identification of two early blood biomarkers ACHE and CLEC12A for improved risk stratification of critically ill COVID-19 patients. | 1 |
| 37102643 | 2023 | Behçet syndrome: The disturbed balance between anti- (CLEC12A, CLC) and proinflammatory (IFI27) gene expressions. | 1 |
| 35481814 | 2022 | CLEC12A plays an important role in immunomodulatory function and prognostic significance of patients with acute myeloid leukemia. | 1 |
| 35481814 | 2022 | CLEC12A plays an important role in immunomodulatory function and prognostic significance of patients with acute myeloid leukemia. | 1 |
| 33094319 | 2021 | CLEC12A and CD33 coexpression as a preferential target for pediatric AML combinatorial immunotherapy. | 36 |
| 33095915 | 2021 | Blast cells in acute megakaryoblastic leukaemia with Down syndrome are characterized by low CLEC12A expression. | 0 |
| 33369070 | 2021 | Exploring blast composition in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms: CD45RA and CD371 improve diagnostic value of flow cytometry through assessment of myeloblast heterogeneity and stem cell aberrancy. | 6 |
Citation
Dessen P
CLEC12A (C-type lectin domain family 12 member A)
Atlas Genet Cytogenet Oncol Haematol. 2007-12-01
Online version: http://atlasgeneticsoncology.org/gene/49855/clec12a
