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CLEC18A (C-type lectin domain family 18 member A)

Identity

Alias_namesC-type lectin domain family 18, member A
Alias_symbol (synonym)MRCL
Other aliasMRCL1
MRLP2
HGNC (Hugo) CLEC18A
LocusID (NCBI) 348174
Atlas_Id 61867
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 69950705 and ends at 69964347 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CLEC18A (16q22.1) / AMPD3 (11p15.4)CLEC18A (16q22.1) / CLEC18A (16q22.1)CLEC18A (16q22.1) / LOC283922 (16q23.1)
CLEC18A (16q22.1) / LTBP1 (2p22.3)CLEC18A (16q22.1) / PRRC2B (9q34.13)NXF1 (11q12.3) / CLEC18A (16q22.1)
RPS20 (8q12.1) / CLEC18A (16q22.1)TP53BP1 (15q15.3) / CLEC18A (16q22.1)WWC3 (Xp22.2) / CLEC18A (16q22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLEC18A   30388
Cards
Entrez_Gene (NCBI)CLEC18A  348174  C-type lectin domain family 18 member A
AliasesMRCL; MRCL1; MRLP2
GeneCards (Weizmann)CLEC18A
Ensembl hg19 (Hinxton)ENSG00000157322 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157322 [Gene_View]  chr16:69950705-69964347 [Contig_View]  CLEC18A [Vega]
ICGC DataPortalENSG00000157322
TCGA cBioPortalCLEC18A
AceView (NCBI)CLEC18A
Genatlas (Paris)CLEC18A
WikiGenes348174
SOURCE (Princeton)CLEC18A
Genetics Home Reference (NIH)CLEC18A
Genomic and cartography
GoldenPath hg38 (UCSC)CLEC18A  -     chr16:69950705-69964347 +  16q22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLEC18A  -     16q22.1   [Description]    (hg19-Feb_2009)
EnsemblCLEC18A - 16q22.1 [CytoView hg19]  CLEC18A - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBICLEC18A [Mapview hg19]  CLEC18A [Mapview hg38]
OMIM616571   
Gene and transcription
Genbank (Entrez)AF428259 AF521893 AK074773 AK096051 AK289884
RefSeq transcript (Entrez)NM_001136214 NM_001271197 NM_182619
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLEC18A
Cluster EST : UnigeneHs.592064 [ NCBI ]
CGAP (NCI)Hs.592064
Alternative Splicing GalleryENSG00000157322
Gene ExpressionCLEC18A [ NCBI-GEO ]   CLEC18A [ EBI - ARRAY_EXPRESS ]   CLEC18A [ SEEK ]   CLEC18A [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC18A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)348174
GTEX Portal (Tissue expression)CLEC18A
Protein : pattern, domain, 3D structure
UniProt/SwissProtA5D8T8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA5D8T8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA5D8T8
Splice isoforms : SwissVarA5D8T8
PhosPhoSitePlusA5D8T8
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_1 (PS00615)    C_TYPE_LECTIN_2 (PS50041)    EGF_1 (PS00022)    EGF_2 (PS01186)    EGF_3 (PS50026)   
Domains : Interpro (EBI)Allrgn_V5/Tpx1    C-type_lectin-like    C-type_lectin-like/link    C-type_lectin_CS    CAP_domain    CTDL_fold    EGF-like_CS    EGF-like_dom   
Domain families : Pfam (Sanger)CAP (PF00188)    Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00188    pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  EGF (SM00181)  SCP (SM00198)  
Conserved Domain (NCBI)CLEC18A
DMDM Disease mutations348174
Blocks (Seattle)CLEC18A
SuperfamilyA5D8T8
Human Protein AtlasENSG00000157322
Peptide AtlasA5D8T8
HPRD17360
IPIIPI00888010   IPI00887415   IPI01011175   IPI01018744   IPI01012354   IPI01026410   IPI00980941   
Protein Interaction databases
DIP (DOE-UCLA)A5D8T8
IntAct (EBI)A5D8T8
FunCoupENSG00000157322
BioGRIDCLEC18A
STRING (EMBL)CLEC18A
ZODIACCLEC18A
Ontologies - Pathways
QuickGOA5D8T8
Ontology : AmiGOprotein binding  extracellular space  endosome  endoplasmic reticulum  Golgi apparatus  polysaccharide binding  
Ontology : EGO-EBIprotein binding  extracellular space  endosome  endoplasmic reticulum  Golgi apparatus  polysaccharide binding  
NDEx NetworkCLEC18A
Atlas of Cancer Signalling NetworkCLEC18A
Wikipedia pathwaysCLEC18A
Orthology - Evolution
OrthoDB348174
GeneTree (enSembl)ENSG00000157322
Phylogenetic Trees/Animal Genes : TreeFamCLEC18A
HOVERGENA5D8T8
HOGENOMA5D8T8
Homologs : HomoloGeneCLEC18A
Homology/Alignments : Family Browser (UCSC)CLEC18A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC18A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC18A
dbVarCLEC18A
ClinVarCLEC18A
1000_GenomesCLEC18A 
Exome Variant ServerCLEC18A
ExAC (Exome Aggregation Consortium)CLEC18A (select the gene name)
Genetic variants : HAPMAP348174
Genomic Variants (DGV)CLEC18A [DGVbeta]
DECIPHERCLEC18A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLEC18A 
Mutations
ICGC Data PortalCLEC18A 
TCGA Data PortalCLEC18A 
Broad Tumor PortalCLEC18A
OASIS PortalCLEC18A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC18A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLEC18A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLEC18A
DgiDB (Drug Gene Interaction Database)CLEC18A
DoCM (Curated mutations)CLEC18A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC18A (select a term)
intoGenCLEC18A
Cancer3DCLEC18A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616571   
Orphanet
MedgenCLEC18A
Genetic Testing Registry CLEC18A
NextProtA5D8T8 [Medical]
TSGene348174
GENETestsCLEC18A
Target ValidationCLEC18A
Huge Navigator CLEC18A [HugePedia]
snp3D : Map Gene to Disease348174
BioCentury BCIQCLEC18A
ClinGenCLEC18A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD348174
Chemical/Pharm GKB GenePA164717976
Clinical trialCLEC18A
Miscellaneous
canSAR (ICR)CLEC18A (select the gene name)
Probes
Litterature
PubMed9 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC18A
EVEXCLEC18A
GoPubMedCLEC18A
iHOPCLEC18A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:43:49 CEST 2017

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