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CLEC3B (C-type lectin domain family 3 member B)

Identity

Alias_namesTNA
tetranectin (plasminogen binding protein)
C-type lectin domain family 3, member B
Alias_symbol (synonym)TN
Other alias
HGNC (Hugo) CLEC3B
LocusID (NCBI) 7123
Atlas_Id 43721
Location 3p21.31  [Link to chromosome band 3p21]
Location_base_pair Starts at 45071622 and ends at 45077565 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CLEC3B (3p21.31) / NPIPB7 (16q23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLEC3B   11891
Cards
Entrez_Gene (NCBI)CLEC3B  7123  C-type lectin domain family 3 member B
AliasesTN; TNA
GeneCards (Weizmann)CLEC3B
Ensembl hg19 (Hinxton)ENSG00000163815 [Gene_View]  chr3:45071622-45077565 [Contig_View]  CLEC3B [Vega]
Ensembl hg38 (Hinxton)ENSG00000163815 [Gene_View]  chr3:45071622-45077565 [Contig_View]  CLEC3B [Vega]
ICGC DataPortalENSG00000163815
TCGA cBioPortalCLEC3B
AceView (NCBI)CLEC3B
Genatlas (Paris)CLEC3B
WikiGenes7123
SOURCE (Princeton)CLEC3B
Genetics Home Reference (NIH)CLEC3B
Genomic and cartography
GoldenPath hg19 (UCSC)CLEC3B  -     chr3:45071622-45077565 +  3p21.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CLEC3B  -     3p21.31   [Description]    (hg38-Dec_2013)
EnsemblCLEC3B - 3p21.31 [CytoView hg19]  CLEC3B - 3p21.31 [CytoView hg38]
Mapping of homologs : NCBICLEC3B [Mapview hg19]  CLEC3B [Mapview hg38]
OMIM187520   
Gene and transcription
Genbank (Entrez)AK312093 BC011024 BI826174 BI826652 BI837909
RefSeq transcript (Entrez)NM_001308394 NM_003278
RefSeq genomic (Entrez)NC_000003 NC_018914 NT_022517 NW_004929309
Consensus coding sequences : CCDS (NCBI)CLEC3B
Cluster EST : UnigeneHs.476092 [ NCBI ]
CGAP (NCI)Hs.476092
Alternative Splicing GalleryENSG00000163815
Gene ExpressionCLEC3B [ NCBI-GEO ]   CLEC3B [ EBI - ARRAY_EXPRESS ]   CLEC3B [ SEEK ]   CLEC3B [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC3B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7123
GTEX Portal (Tissue expression)CLEC3B
Protein : pattern, domain, 3D structure
UniProt/SwissProtP05452   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP05452  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP05452
Splice isoforms : SwissVarP05452
PhosPhoSitePlusP05452
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_1 (PS00615)    C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin    C-type_lectin-like    C-type_lectin_CS    C-type_lectin_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)CLEC3B
DMDM Disease mutations7123
Blocks (Seattle)CLEC3B
PDB (SRS)1HTN    1RJH    1TN3    3L9J   
PDB (PDBSum)1HTN    1RJH    1TN3    3L9J   
PDB (IMB)1HTN    1RJH    1TN3    3L9J   
PDB (RSDB)1HTN    1RJH    1TN3    3L9J   
Structural Biology KnowledgeBase1HTN    1RJH    1TN3    3L9J   
SCOP (Structural Classification of Proteins)1HTN    1RJH    1TN3    3L9J   
CATH (Classification of proteins structures)1HTN    1RJH    1TN3    3L9J   
SuperfamilyP05452
Human Protein AtlasENSG00000163815
Peptide AtlasP05452
HPRD01759
IPIIPI00009028   IPI00792115   
Protein Interaction databases
DIP (DOE-UCLA)P05452
IntAct (EBI)P05452
FunCoupENSG00000163815
BioGRIDCLEC3B
STRING (EMBL)CLEC3B
ZODIACCLEC3B
Ontologies - Pathways
QuickGOP05452
Ontology : AmiGOossification  granular component  platelet degranulation  calcium ion binding  extracellular region  extracellular region  extracellular space  cytoplasm  heparin binding  positive regulation of plasminogen activation  carbohydrate binding  bone mineralization  bone mineralization  extracellular matrix  platelet dense granule lumen  kringle domain binding  extracellular exosome  cellular response to organic substance  cellular response to transforming growth factor beta stimulus  
Ontology : EGO-EBIossification  granular component  platelet degranulation  calcium ion binding  extracellular region  extracellular region  extracellular space  cytoplasm  heparin binding  positive regulation of plasminogen activation  carbohydrate binding  bone mineralization  bone mineralization  extracellular matrix  platelet dense granule lumen  kringle domain binding  extracellular exosome  cellular response to organic substance  cellular response to transforming growth factor beta stimulus  
NDEx NetworkCLEC3B
Atlas of Cancer Signalling NetworkCLEC3B
Wikipedia pathwaysCLEC3B
Orthology - Evolution
OrthoDB7123
GeneTree (enSembl)ENSG00000163815
Phylogenetic Trees/Animal Genes : TreeFamCLEC3B
HOVERGENP05452
HOGENOMP05452
Homologs : HomoloGeneCLEC3B
Homology/Alignments : Family Browser (UCSC)CLEC3B
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC3B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC3B
dbVarCLEC3B
ClinVarCLEC3B
1000_GenomesCLEC3B 
Exome Variant ServerCLEC3B
ExAC (Exome Aggregation Consortium)CLEC3B (select the gene name)
Genetic variants : HAPMAP7123
Genomic Variants (DGV)CLEC3B [DGVbeta]
DECIPHER (Syndromes)3:45071622-45077565  ENSG00000163815
CONAN: Copy Number AnalysisCLEC3B 
Mutations
ICGC Data PortalCLEC3B 
TCGA Data PortalCLEC3B 
Broad Tumor PortalCLEC3B
OASIS PortalCLEC3B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC3B  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLEC3B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLEC3B
DgiDB (Drug Gene Interaction Database)CLEC3B
DoCM (Curated mutations)CLEC3B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC3B (select a term)
intoGenCLEC3B
Cancer3DCLEC3B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM187520   
Orphanet
MedgenCLEC3B
Genetic Testing Registry CLEC3B
NextProtP05452 [Medical]
TSGene7123
GENETestsCLEC3B
Huge Navigator CLEC3B [HugePedia]
snp3D : Map Gene to Disease7123
BioCentury BCIQCLEC3B
ClinGenCLEC3B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7123
Chemical/Pharm GKB GenePA36590
Clinical trialCLEC3B
Miscellaneous
canSAR (ICR)CLEC3B (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC3B
EVEXCLEC3B
GoPubMedCLEC3B
iHOPCLEC3B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:00:48 CET 2017

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