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CLEC4A (C-type lectin domain family 4 member A)

Identity

Alias_namesCLECSF6
C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 6
C-type lectin domain family 4, member A
Alias_symbol (synonym)DCIR
DDB27
CD367
Other aliasHDCGC13P
LLIR
HGNC (Hugo) CLEC4A
LocusID (NCBI) 50856
Atlas_Id 61874
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 8123632 and ends at 8138607 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLEC4A   13257
Cards
Entrez_Gene (NCBI)CLEC4A  50856  C-type lectin domain family 4 member A
AliasesCD367; CLECSF6; DCIR; DDB27; 
HDCGC13P; LLIR
GeneCards (Weizmann)CLEC4A
Ensembl hg19 (Hinxton)ENSG00000111729 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000111729 [Gene_View]  chr12:8123632-8138607 [Contig_View]  CLEC4A [Vega]
ICGC DataPortalENSG00000111729
TCGA cBioPortalCLEC4A
AceView (NCBI)CLEC4A
Genatlas (Paris)CLEC4A
WikiGenes50856
SOURCE (Princeton)CLEC4A
Genetics Home Reference (NIH)CLEC4A
Genomic and cartography
GoldenPath hg38 (UCSC)CLEC4A  -     chr12:8123632-8138607 +  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLEC4A  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblCLEC4A - 12p13.31 [CytoView hg19]  CLEC4A - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBICLEC4A [Mapview hg19]  CLEC4A [Mapview hg38]
OMIM605306   
Gene and transcription
Genbank (Entrez)AA418441 AF067800 AF109146 AF200738 AF328684
RefSeq transcript (Entrez)NM_016184 NM_194447 NM_194448 NM_194450
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLEC4A
Cluster EST : UnigeneHs.504657 [ NCBI ]
CGAP (NCI)Hs.504657
Alternative Splicing GalleryENSG00000111729
Gene ExpressionCLEC4A [ NCBI-GEO ]   CLEC4A [ EBI - ARRAY_EXPRESS ]   CLEC4A [ SEEK ]   CLEC4A [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC4A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)50856
GTEX Portal (Tissue expression)CLEC4A
Human Protein AtlasENSG00000111729-CLEC4A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UMR7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UMR7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UMR7
Splice isoforms : SwissVarQ9UMR7
PhosPhoSitePlusQ9UMR7
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_1 (PS00615)    C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    C-type_lectin_CS    CD209-like_CTLD    CTDL_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)CLEC4A
DMDM Disease mutations50856
Blocks (Seattle)CLEC4A
PDB (SRS)5B1W    5B1X   
PDB (PDBSum)5B1W    5B1X   
PDB (IMB)5B1W    5B1X   
PDB (RSDB)5B1W    5B1X   
Structural Biology KnowledgeBase5B1W    5B1X   
SCOP (Structural Classification of Proteins)5B1W    5B1X   
CATH (Classification of proteins structures)5B1W    5B1X   
SuperfamilyQ9UMR7
Human Protein Atlas [tissue]ENSG00000111729-CLEC4A [tissue]
Peptide AtlasQ9UMR7
HPRD05604
IPIIPI00299937   IPI00301218   IPI00414797   IPI00375717   IPI01015567   
Protein Interaction databases
DIP (DOE-UCLA)Q9UMR7
IntAct (EBI)Q9UMR7
FunCoupENSG00000111729
BioGRIDCLEC4A
STRING (EMBL)CLEC4A
ZODIACCLEC4A
Ontologies - Pathways
QuickGOQ9UMR7
Ontology : AmiGOstimulatory C-type lectin receptor signaling pathway  adaptive immune response  transmembrane signaling receptor activity  plasma membrane  integral component of plasma membrane  cell adhesion  cell surface receptor signaling pathway  carbohydrate binding  innate immune response  
Ontology : EGO-EBIstimulatory C-type lectin receptor signaling pathway  adaptive immune response  transmembrane signaling receptor activity  plasma membrane  integral component of plasma membrane  cell adhesion  cell surface receptor signaling pathway  carbohydrate binding  innate immune response  
NDEx NetworkCLEC4A
Atlas of Cancer Signalling NetworkCLEC4A
Wikipedia pathwaysCLEC4A
Orthology - Evolution
OrthoDB50856
GeneTree (enSembl)ENSG00000111729
Phylogenetic Trees/Animal Genes : TreeFamCLEC4A
HOVERGENQ9UMR7
HOGENOMQ9UMR7
Homologs : HomoloGeneCLEC4A
Homology/Alignments : Family Browser (UCSC)CLEC4A
Gene fusions - Rearrangements
Tumor Fusion PortalCLEC4A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC4A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC4A
dbVarCLEC4A
ClinVarCLEC4A
1000_GenomesCLEC4A 
Exome Variant ServerCLEC4A
ExAC (Exome Aggregation Consortium)ENSG00000111729
GNOMAD BrowserENSG00000111729
Genetic variants : HAPMAP50856
Genomic Variants (DGV)CLEC4A [DGVbeta]
DECIPHERCLEC4A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLEC4A 
Mutations
ICGC Data PortalCLEC4A 
TCGA Data PortalCLEC4A 
Broad Tumor PortalCLEC4A
OASIS PortalCLEC4A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC4A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLEC4A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLEC4A
DgiDB (Drug Gene Interaction Database)CLEC4A
DoCM (Curated mutations)CLEC4A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC4A (select a term)
intoGenCLEC4A
Cancer3DCLEC4A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605306   
Orphanet
DisGeNETCLEC4A
MedgenCLEC4A
Genetic Testing Registry CLEC4A
NextProtQ9UMR7 [Medical]
TSGene50856
GENETestsCLEC4A
Target ValidationCLEC4A
Huge Navigator CLEC4A [HugePedia]
snp3D : Map Gene to Disease50856
BioCentury BCIQCLEC4A
ClinGenCLEC4A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD50856
Chemical/Pharm GKB GenePA26584
Clinical trialCLEC4A
Miscellaneous
canSAR (ICR)CLEC4A (select the gene name)
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC4A
EVEXCLEC4A
GoPubMedCLEC4A
iHOPCLEC4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:26:00 CET 2017

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