Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CLEC4C (C-type lectin domain family 4 member C)

Identity

Alias_namesCLECSF11
CLECSF7
C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 7
C-type lectin domain family 4, member C
Alias_symbol (synonym)HECL
DLEC
BDCA2
CD303
Other aliasPRO34150
HGNC (Hugo) CLEC4C
LocusID (NCBI) 170482
Atlas_Id 51423
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 7729415 and ends at 7749473 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLEC4C   13258
Cards
Entrez_Gene (NCBI)CLEC4C  170482  C-type lectin domain family 4 member C
AliasesBDCA2; CD303; CLECSF11; CLECSF7; 
DLEC; HECL; PRO34150
GeneCards (Weizmann)CLEC4C
Ensembl hg19 (Hinxton)ENSG00000198178 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000198178 [Gene_View]  chr12:7729415-7749473 [Contig_View]  CLEC4C [Vega]
ICGC DataPortalENSG00000198178
TCGA cBioPortalCLEC4C
AceView (NCBI)CLEC4C
Genatlas (Paris)CLEC4C
WikiGenes170482
SOURCE (Princeton)CLEC4C
Genetics Home Reference (NIH)CLEC4C
Genomic and cartography
GoldenPath hg38 (UCSC)CLEC4C  -     chr12:7729415-7749473 -  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLEC4C  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblCLEC4C - 12p13.31 [CytoView hg19]  CLEC4C - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBICLEC4C [Mapview hg19]  CLEC4C [Mapview hg38]
OMIM606677   
Gene and transcription
Genbank (Entrez)AF293615 AF325459 AF325460 AK122596 AY358223
RefSeq transcript (Entrez)NM_130441 NM_203503
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLEC4C
Cluster EST : UnigeneHs.351812 [ NCBI ]
CGAP (NCI)Hs.351812
Alternative Splicing GalleryENSG00000198178
Gene ExpressionCLEC4C [ NCBI-GEO ]   CLEC4C [ EBI - ARRAY_EXPRESS ]   CLEC4C [ SEEK ]   CLEC4C [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC4C [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)170482
GTEX Portal (Tissue expression)CLEC4C
Human Protein AtlasENSG00000198178-CLEC4C [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WTT0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WTT0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WTT0
Splice isoforms : SwissVarQ8WTT0
PhosPhoSitePlusQ8WTT0
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_1 (PS00615)    C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    C-type_lectin_CS    CD209-like_CTLD    CTDL_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)CLEC4C
DMDM Disease mutations170482
Blocks (Seattle)CLEC4C
PDB (SRS)3WBP    3WBQ    3WBR    4ZES    4ZET   
PDB (PDBSum)3WBP    3WBQ    3WBR    4ZES    4ZET   
PDB (IMB)3WBP    3WBQ    3WBR    4ZES    4ZET   
PDB (RSDB)3WBP    3WBQ    3WBR    4ZES    4ZET   
Structural Biology KnowledgeBase3WBP    3WBQ    3WBR    4ZES    4ZET   
SCOP (Structural Classification of Proteins)3WBP    3WBQ    3WBR    4ZES    4ZET   
CATH (Classification of proteins structures)3WBP    3WBQ    3WBR    4ZES    4ZET   
SuperfamilyQ8WTT0
Human Protein Atlas [tissue]ENSG00000198178-CLEC4C [tissue]
Peptide AtlasQ8WTT0
HPRD09453
IPIIPI00102814   IPI00179249   IPI01009579   IPI01009138   
Protein Interaction databases
DIP (DOE-UCLA)Q8WTT0
IntAct (EBI)Q8WTT0
FunCoupENSG00000198178
BioGRIDCLEC4C
STRING (EMBL)CLEC4C
ZODIACCLEC4C
Ontologies - Pathways
QuickGOQ8WTT0
Ontology : AmiGOstimulatory C-type lectin receptor signaling pathway  adaptive immune response  plasma membrane  integral component of membrane  carbohydrate binding  secretory granule membrane  neutrophil degranulation  innate immune response  tertiary granule membrane  ficolin-1-rich granule membrane  
Ontology : EGO-EBIstimulatory C-type lectin receptor signaling pathway  adaptive immune response  plasma membrane  integral component of membrane  carbohydrate binding  secretory granule membrane  neutrophil degranulation  innate immune response  tertiary granule membrane  ficolin-1-rich granule membrane  
NDEx NetworkCLEC4C
Atlas of Cancer Signalling NetworkCLEC4C
Wikipedia pathwaysCLEC4C
Orthology - Evolution
OrthoDB170482
GeneTree (enSembl)ENSG00000198178
Phylogenetic Trees/Animal Genes : TreeFamCLEC4C
HOVERGENQ8WTT0
HOGENOMQ8WTT0
Homologs : HomoloGeneCLEC4C
Homology/Alignments : Family Browser (UCSC)CLEC4C
Gene fusions - Rearrangements
Tumor Fusion PortalCLEC4C
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC4C [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC4C
dbVarCLEC4C
ClinVarCLEC4C
1000_GenomesCLEC4C 
Exome Variant ServerCLEC4C
ExAC (Exome Aggregation Consortium)ENSG00000198178
GNOMAD BrowserENSG00000198178
Genetic variants : HAPMAP170482
Genomic Variants (DGV)CLEC4C [DGVbeta]
DECIPHERCLEC4C [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLEC4C 
Mutations
ICGC Data PortalCLEC4C 
TCGA Data PortalCLEC4C 
Broad Tumor PortalCLEC4C
OASIS PortalCLEC4C [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC4C  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLEC4C
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLEC4C
DgiDB (Drug Gene Interaction Database)CLEC4C
DoCM (Curated mutations)CLEC4C (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC4C (select a term)
intoGenCLEC4C
Cancer3DCLEC4C(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606677   
Orphanet
DisGeNETCLEC4C
MedgenCLEC4C
Genetic Testing Registry CLEC4C
NextProtQ8WTT0 [Medical]
TSGene170482
GENETestsCLEC4C
Target ValidationCLEC4C
Huge Navigator CLEC4C [HugePedia]
snp3D : Map Gene to Disease170482
BioCentury BCIQCLEC4C
ClinGenCLEC4C
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD170482
Chemical/Pharm GKB GenePA26585
Clinical trialCLEC4C
Miscellaneous
canSAR (ICR)CLEC4C (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC4C
EVEXCLEC4C
GoPubMedCLEC4C
iHOPCLEC4C
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:08:04 CET 2017

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