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CLEC4E (C-type lectin domain family 4 member E)

Identity

Alias_namesCLECSF9
C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 9
C-type lectin domain family 4, member E
Alias_symbol (synonym)mincle
Other aliasMINCLE
HGNC (Hugo) CLEC4E
LocusID (NCBI) 26253
Atlas_Id 61876
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 8533305 and ends at 8540962 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLEC4E   14555
Cards
Entrez_Gene (NCBI)CLEC4E  26253  C-type lectin domain family 4 member E
AliasesCLECSF9; MINCLE
GeneCards (Weizmann)CLEC4E
Ensembl hg19 (Hinxton)ENSG00000166523 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000166523 [Gene_View]  chr12:8533305-8540962 [Contig_View]  CLEC4E [Vega]
ICGC DataPortalENSG00000166523
TCGA cBioPortalCLEC4E
AceView (NCBI)CLEC4E
Genatlas (Paris)CLEC4E
WikiGenes26253
SOURCE (Princeton)CLEC4E
Genetics Home Reference (NIH)CLEC4E
Genomic and cartography
GoldenPath hg38 (UCSC)CLEC4E  -     chr12:8533305-8540962 -  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLEC4E  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblCLEC4E - 12p13.31 [CytoView hg19]  CLEC4E - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBICLEC4E [Mapview hg19]  CLEC4E [Mapview hg38]
OMIM609962   
Gene and transcription
Genbank (Entrez)AB024718 AK312671 AY358499 BC000715 DA669951
RefSeq transcript (Entrez)NM_014358
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLEC4E
Cluster EST : UnigeneHs.236516 [ NCBI ]
CGAP (NCI)Hs.236516
Alternative Splicing GalleryENSG00000166523
Gene ExpressionCLEC4E [ NCBI-GEO ]   CLEC4E [ EBI - ARRAY_EXPRESS ]   CLEC4E [ SEEK ]   CLEC4E [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC4E [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26253
GTEX Portal (Tissue expression)CLEC4E
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9ULY5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9ULY5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9ULY5
Splice isoforms : SwissVarQ9ULY5
PhosPhoSitePlusQ9ULY5
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link    CD209-like_CTLD    CTDL_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)CLEC4E
DMDM Disease mutations26253
Blocks (Seattle)CLEC4E
PDB (SRS)3WH2    3WH3   
PDB (PDBSum)3WH2    3WH3   
PDB (IMB)3WH2    3WH3   
PDB (RSDB)3WH2    3WH3   
Structural Biology KnowledgeBase3WH2    3WH3   
SCOP (Structural Classification of Proteins)3WH2    3WH3   
CATH (Classification of proteins structures)3WH2    3WH3   
SuperfamilyQ9ULY5
Human Protein AtlasENSG00000166523
Peptide AtlasQ9ULY5
HPRD13075
IPIIPI00003869   IPI00942786   IPI01009489   IPI01010761   
Protein Interaction databases
DIP (DOE-UCLA)Q9ULY5
IntAct (EBI)Q9ULY5
FunCoupENSG00000166523
BioGRIDCLEC4E
STRING (EMBL)CLEC4E
ZODIACCLEC4E
Ontologies - Pathways
QuickGOQ9ULY5
Ontology : AmiGOstimulatory C-type lectin receptor signaling pathway  T cell differentiation involved in immune response  receptor activity  plasma membrane  integral component of membrane  carbohydrate binding  Fc-gamma receptor signaling pathway  defense response to bacterium  innate immune response  positive regulation of cytokine secretion  
Ontology : EGO-EBIstimulatory C-type lectin receptor signaling pathway  T cell differentiation involved in immune response  receptor activity  plasma membrane  integral component of membrane  carbohydrate binding  Fc-gamma receptor signaling pathway  defense response to bacterium  innate immune response  positive regulation of cytokine secretion  
Pathways : KEGGTuberculosis   
NDEx NetworkCLEC4E
Atlas of Cancer Signalling NetworkCLEC4E
Wikipedia pathwaysCLEC4E
Orthology - Evolution
OrthoDB26253
GeneTree (enSembl)ENSG00000166523
Phylogenetic Trees/Animal Genes : TreeFamCLEC4E
HOVERGENQ9ULY5
HOGENOMQ9ULY5
Homologs : HomoloGeneCLEC4E
Homology/Alignments : Family Browser (UCSC)CLEC4E
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC4E [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC4E
dbVarCLEC4E
ClinVarCLEC4E
1000_GenomesCLEC4E 
Exome Variant ServerCLEC4E
ExAC (Exome Aggregation Consortium)CLEC4E (select the gene name)
Genetic variants : HAPMAP26253
Genomic Variants (DGV)CLEC4E [DGVbeta]
DECIPHERCLEC4E [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLEC4E 
Mutations
ICGC Data PortalCLEC4E 
TCGA Data PortalCLEC4E 
Broad Tumor PortalCLEC4E
OASIS PortalCLEC4E [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC4E  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLEC4E
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLEC4E
DgiDB (Drug Gene Interaction Database)CLEC4E
DoCM (Curated mutations)CLEC4E (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC4E (select a term)
intoGenCLEC4E
Cancer3DCLEC4E(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609962   
Orphanet
MedgenCLEC4E
Genetic Testing Registry CLEC4E
NextProtQ9ULY5 [Medical]
TSGene26253
GENETestsCLEC4E
Target ValidationCLEC4E
Huge Navigator CLEC4E [HugePedia]
snp3D : Map Gene to Disease26253
BioCentury BCIQCLEC4E
ClinGenCLEC4E
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26253
Chemical/Pharm GKB GenePA26586
Clinical trialCLEC4E
Miscellaneous
canSAR (ICR)CLEC4E (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC4E
EVEXCLEC4E
GoPubMedCLEC4E
iHOPCLEC4E
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:43:51 CEST 2017

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