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CLEC5A (C-type lectin domain family 5, member A)

Identity

Alias_namesCLECSF5
C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 5
C-type lectin domain family 5, member A
Alias_symbol (synonym)MDL-1
Other aliasMDL1
HGNC (Hugo) CLEC5A
LocusID (NCBI) 23601
Atlas_Id 61879
Location 7q34  [Link to chromosome band 7q34]
Location_base_pair Starts at 141627157 and ends at 141646807 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLEC5A   2054
Cards
Entrez_Gene (NCBI)CLEC5A  23601  C-type lectin domain family 5, member A
AliasesCLECSF5; MDL-1; MDL1
GeneCards (Weizmann)CLEC5A
Ensembl hg19 (Hinxton)ENSG00000258227 [Gene_View]  chr7:141627157-141646807 [Contig_View]  CLEC5A [Vega]
Ensembl hg38 (Hinxton)ENSG00000258227 [Gene_View]  chr7:141627157-141646807 [Contig_View]  CLEC5A [Vega]
ICGC DataPortalENSG00000258227
TCGA cBioPortalCLEC5A
AceView (NCBI)CLEC5A
Genatlas (Paris)CLEC5A
WikiGenes23601
SOURCE (Princeton)CLEC5A
Genetics Home Reference (NIH)CLEC5A
Genomic and cartography
GoldenPath hg19 (UCSC)CLEC5A  -     chr7:141627157-141646807 -  7q34   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CLEC5A  -     7q34   [Description]    (hg38-Dec_2013)
EnsemblCLEC5A - 7q34 [CytoView hg19]  CLEC5A - 7q34 [CytoView hg38]
Mapping of homologs : NCBICLEC5A [Mapview hg19]  CLEC5A [Mapview hg38]
OMIM604987   
Gene and transcription
Genbank (Entrez)AF139768 AI418484 AJ271684 AK292766 AK295200
RefSeq transcript (Entrez)NM_001301167 NM_013252
RefSeq genomic (Entrez)NC_000007 NC_018918 NT_007933 NW_004929333
Consensus coding sequences : CCDS (NCBI)CLEC5A
Cluster EST : UnigeneHs.446235 [ NCBI ]
CGAP (NCI)Hs.446235
Alternative Splicing GalleryENSG00000258227
Gene ExpressionCLEC5A [ NCBI-GEO ]   CLEC5A [ EBI - ARRAY_EXPRESS ]   CLEC5A [ SEEK ]   CLEC5A [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC5A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23601
GTEX Portal (Tissue expression)CLEC5A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NY25   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NY25  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NY25
Splice isoforms : SwissVarQ9NY25
PhosPhoSitePlusQ9NY25
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin    C-type_lectin-like    C-type_lectin_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)CLEC5A
DMDM Disease mutations23601
Blocks (Seattle)CLEC5A
PDB (SRS)2YHF   
PDB (PDBSum)2YHF   
PDB (IMB)2YHF   
PDB (RSDB)2YHF   
Structural Biology KnowledgeBase2YHF   
SCOP (Structural Classification of Proteins)2YHF   
CATH (Classification of proteins structures)2YHF   
SuperfamilyQ9NY25
Human Protein AtlasENSG00000258227
Peptide AtlasQ9NY25
HPRD09229
IPIIPI00001675   IPI00552895   IPI00924938   IPI00784462   IPI00924532   IPI00924655   
Protein Interaction databases
DIP (DOE-UCLA)Q9NY25
IntAct (EBI)Q9NY25
FunCoupENSG00000258227
BioGRIDCLEC5A
STRING (EMBL)CLEC5A
ZODIACCLEC5A
Ontologies - Pathways
QuickGOQ9NY25
Ontology : AmiGOvirus receptor activity  osteoblast development  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  response to virus  cell surface  myeloid cell differentiation  carbohydrate binding  negative regulation of myeloid cell apoptotic process  negative regulation of apoptotic process  innate immune response  innate immune response  viral entry into host cell  viral entry into host cell  positive regulation of cytokine secretion  
Ontology : EGO-EBIvirus receptor activity  osteoblast development  plasma membrane  integral component of plasma membrane  cellular defense response  signal transduction  response to virus  cell surface  myeloid cell differentiation  carbohydrate binding  negative regulation of myeloid cell apoptotic process  negative regulation of apoptotic process  innate immune response  innate immune response  viral entry into host cell  viral entry into host cell  positive regulation of cytokine secretion  
NDEx NetworkCLEC5A
Atlas of Cancer Signalling NetworkCLEC5A
Wikipedia pathwaysCLEC5A
Orthology - Evolution
OrthoDB23601
GeneTree (enSembl)ENSG00000258227
Phylogenetic Trees/Animal Genes : TreeFamCLEC5A
HOVERGENQ9NY25
HOGENOMQ9NY25
Homologs : HomoloGeneCLEC5A
Homology/Alignments : Family Browser (UCSC)CLEC5A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC5A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC5A
dbVarCLEC5A
ClinVarCLEC5A
1000_GenomesCLEC5A 
Exome Variant ServerCLEC5A
ExAC (Exome Aggregation Consortium)CLEC5A (select the gene name)
Genetic variants : HAPMAP23601
Genomic Variants (DGV)CLEC5A [DGVbeta]
DECIPHER (Syndromes)7:141627157-141646807  ENSG00000258227
CONAN: Copy Number AnalysisCLEC5A 
Mutations
ICGC Data PortalCLEC5A 
TCGA Data PortalCLEC5A 
Broad Tumor PortalCLEC5A
OASIS PortalCLEC5A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC5A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLEC5A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLEC5A
DgiDB (Drug Gene Interaction Database)CLEC5A
DoCM (Curated mutations)CLEC5A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC5A (select a term)
intoGenCLEC5A
Cancer3DCLEC5A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604987   
Orphanet
MedgenCLEC5A
Genetic Testing Registry CLEC5A
NextProtQ9NY25 [Medical]
TSGene23601
GENETestsCLEC5A
Huge Navigator CLEC5A [HugePedia]
snp3D : Map Gene to Disease23601
BioCentury BCIQCLEC5A
ClinGenCLEC5A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23601
Chemical/Pharm GKB GenePA26583
Clinical trialCLEC5A
Miscellaneous
canSAR (ICR)CLEC5A (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC5A
EVEXCLEC5A
GoPubMedCLEC5A
iHOPCLEC5A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:59:40 CET 2017

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