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CLEC6A (C-type lectin domain containing 6A)

Identity

Other aliasCLEC4N
CLECSF10
dectin-2
HGNC (Hugo) CLEC6A
LocusID (NCBI) 93978
Atlas_Id 57471
Location 12p13.31  [Link to chromosome band 12p13]
Location_base_pair Starts at 8455995 and ends at 8478330 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  CLEC6A/CLEC4D (12p13)


External links

Nomenclature
HGNC (Hugo)CLEC6A   14556
Cards
Entrez_Gene (NCBI)CLEC6A  93978  C-type lectin domain containing 6A
AliasesCLEC4N; CLECSF10; dectin-2
GeneCards (Weizmann)CLEC6A
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr12:8455995-8478330 [Contig_View]  CLEC6A [Vega]
TCGA cBioPortalCLEC6A
AceView (NCBI)CLEC6A
Genatlas (Paris)CLEC6A
WikiGenes93978
SOURCE (Princeton)CLEC6A
Genetics Home Reference (NIH)CLEC6A
Genomic and cartography
GoldenPath hg38 (UCSC)CLEC6A  -     chr12:8455995-8478330 +  12p13.31   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLEC6A  -     12p13.31   [Description]    (hg19-Feb_2009)
EnsemblCLEC6A - 12p13.31 [CytoView hg19]  CLEC6A - 12p13.31 [CytoView hg38]
Mapping of homologs : NCBICLEC6A [Mapview hg19]  CLEC6A [Mapview hg38]
OMIM613579   
Gene and transcription
Genbank (Entrez)AK308011 AY321309 AY365135 BC132933 BC132935
RefSeq transcript (Entrez)NM_001007033 NM_001317999
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLEC6A
Cluster EST : UnigeneHs.591147 [ NCBI ]
CGAP (NCI)Hs.591147
Gene ExpressionCLEC6A [ NCBI-GEO ]   CLEC6A [ EBI - ARRAY_EXPRESS ]   CLEC6A [ SEEK ]   CLEC6A [ MEM ]
Gene Expression Viewer (FireBrowse)CLEC6A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)93978
GTEX Portal (Tissue expression)CLEC6A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6EIG7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6EIG7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6EIG7
Splice isoforms : SwissVarQ6EIG7
PhosPhoSitePlusQ6EIG7
Domaine pattern : Prosite (Expaxy)C_TYPE_LECTIN_2 (PS50041)   
Domains : Interpro (EBI)C-type_lectin-like    C-type_lectin-like/link_sf    CD209-like_CTLD    CTDL_fold   
Domain families : Pfam (Sanger)Lectin_C (PF00059)   
Domain families : Pfam (NCBI)pfam00059   
Domain families : Smart (EMBL)CLECT (SM00034)  
Conserved Domain (NCBI)CLEC6A
DMDM Disease mutations93978
Blocks (Seattle)CLEC6A
PDB (SRS)5VYB   
PDB (PDBSum)5VYB   
PDB (IMB)5VYB   
PDB (RSDB)5VYB   
Structural Biology KnowledgeBase5VYB   
SCOP (Structural Classification of Proteins)5VYB   
CATH (Classification of proteins structures)5VYB   
SuperfamilyQ6EIG7
Peptide AtlasQ6EIG7
IPIIPI00455618   IPI01018627   
Protein Interaction databases
DIP (DOE-UCLA)Q6EIG7
IntAct (EBI)Q6EIG7
BioGRIDCLEC6A
STRING (EMBL)CLEC6A
ZODIACCLEC6A
Ontologies - Pathways
QuickGOQ6EIG7
Ontology : AmiGOstimulatory C-type lectin receptor signaling pathway  adaptive immune response  calcium ion binding  mannose binding  plasma membrane  integral component of membrane  carbohydrate binding  carbohydrate binding  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  positive regulation of cytokine secretion  defense response to fungus  
Ontology : EGO-EBIstimulatory C-type lectin receptor signaling pathway  adaptive immune response  calcium ion binding  mannose binding  plasma membrane  integral component of membrane  carbohydrate binding  carbohydrate binding  positive regulation of I-kappaB kinase/NF-kappaB signaling  innate immune response  positive regulation of cytokine secretion  defense response to fungus  
NDEx NetworkCLEC6A
Atlas of Cancer Signalling NetworkCLEC6A
Wikipedia pathwaysCLEC6A
Orthology - Evolution
OrthoDB93978
Phylogenetic Trees/Animal Genes : TreeFamCLEC6A
HOVERGENQ6EIG7
HOGENOMQ6EIG7
Homologs : HomoloGeneCLEC6A
Homology/Alignments : Family Browser (UCSC)CLEC6A
Gene fusions - Rearrangements
Fusion : QuiverCLEC6A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLEC6A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLEC6A
dbVarCLEC6A
ClinVarCLEC6A
1000_GenomesCLEC6A 
Exome Variant ServerCLEC6A
Varsome BrowserCLEC6A
Genetic variants : HAPMAP93978
Genomic Variants (DGV)CLEC6A [DGVbeta]
DECIPHERCLEC6A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLEC6A 
Mutations
ICGC Data PortalCLEC6A 
TCGA Data PortalCLEC6A 
Broad Tumor PortalCLEC6A
OASIS PortalCLEC6A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLEC6A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLEC6A
BioMutasearch CLEC6A
DgiDB (Drug Gene Interaction Database)CLEC6A
DoCM (Curated mutations)CLEC6A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLEC6A (select a term)
intoGenCLEC6A
Cancer3DCLEC6A(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613579   
Orphanet
DisGeNETCLEC6A
MedgenCLEC6A
Genetic Testing Registry CLEC6A
NextProtQ6EIG7 [Medical]
TSGene93978
GENETestsCLEC6A
Target ValidationCLEC6A
Huge Navigator CLEC6A [HugePedia]
snp3D : Map Gene to Disease93978
BioCentury BCIQCLEC6A
ClinGenCLEC6A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD93978
Chemical/Pharm GKB GenePA26579
Clinical trialCLEC6A
Miscellaneous
canSAR (ICR)CLEC6A (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLEC6A
EVEXCLEC6A
GoPubMedCLEC6A
iHOPCLEC6A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Aug 27 11:15:54 CEST 2018

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