Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CLIC3 (chloride intracellular channel 3)

Identity

Other alias-
HGNC (Hugo) CLIC3
LocusID (NCBI) 9022
Atlas_Id 55383
Location 9q34.3  [Link to chromosome band 9q34]
Location_base_pair Starts at 136994608 and ends at 136996572 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLIC3   2064
Cards
Entrez_Gene (NCBI)CLIC3  9022  chloride intracellular channel 3
Aliases
GeneCards (Weizmann)CLIC3
Ensembl hg19 (Hinxton)ENSG00000169583 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169583 [Gene_View]  chr9:136994608-136996572 [Contig_View]  CLIC3 [Vega]
ICGC DataPortalENSG00000169583
TCGA cBioPortalCLIC3
AceView (NCBI)CLIC3
Genatlas (Paris)CLIC3
WikiGenes9022
SOURCE (Princeton)CLIC3
Genetics Home Reference (NIH)CLIC3
Genomic and cartography
GoldenPath hg38 (UCSC)CLIC3  -     chr9:136994608-136996572 -  9q34.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLIC3  -     9q34.3   [Description]    (hg19-Feb_2009)
EnsemblCLIC3 - 9q34.3 [CytoView hg19]  CLIC3 - 9q34.3 [CytoView hg38]
Mapping of homologs : NCBICLIC3 [Mapview hg19]  CLIC3 [Mapview hg38]
OMIM606533   
Gene and transcription
Genbank (Entrez)AF102166 AI741256 BC007012 BF439361 BM043659
RefSeq transcript (Entrez)NM_004669
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLIC3
Cluster EST : UnigeneHs.64746 [ NCBI ]
CGAP (NCI)Hs.64746
Alternative Splicing GalleryENSG00000169583
Gene ExpressionCLIC3 [ NCBI-GEO ]   CLIC3 [ EBI - ARRAY_EXPRESS ]   CLIC3 [ SEEK ]   CLIC3 [ MEM ]
Gene Expression Viewer (FireBrowse)CLIC3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9022
GTEX Portal (Tissue expression)CLIC3
Human Protein AtlasENSG00000169583-CLIC3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO95833   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO95833  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO95833
Splice isoforms : SwissVarO95833
PhosPhoSitePlusO95833
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)    GST_NTER (PS50404)   
Domains : Interpro (EBI)CLIC    CLIC-3    Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GST_N_3 (PF13417)   
Domain families : Pfam (NCBI)pfam13417   
Conserved Domain (NCBI)CLIC3
DMDM Disease mutations9022
Blocks (Seattle)CLIC3
PDB (SRS)3FY7    3KJY   
PDB (PDBSum)3FY7    3KJY   
PDB (IMB)3FY7    3KJY   
PDB (RSDB)3FY7    3KJY   
Structural Biology KnowledgeBase3FY7    3KJY   
SCOP (Structural Classification of Proteins)3FY7    3KJY   
CATH (Classification of proteins structures)3FY7    3KJY   
SuperfamilyO95833
Human Protein Atlas [tissue]ENSG00000169583-CLIC3 [tissue]
Peptide AtlasO95833
HPRD05941
IPIIPI00000692   IPI00644062   
Protein Interaction databases
DIP (DOE-UCLA)O95833
IntAct (EBI)O95833
FunCoupENSG00000169583
BioGRIDCLIC3
STRING (EMBL)CLIC3
ZODIACCLIC3
Ontologies - Pathways
QuickGOO95833
Ontology : AmiGOvoltage-gated ion channel activity  chloride channel activity  protein binding  nucleus  cytoplasm  chloride transport  signal transduction  nuclear body  chloride channel complex  regulation of ion transmembrane transport  extracellular exosome  chloride transmembrane transport  
Ontology : EGO-EBIvoltage-gated ion channel activity  chloride channel activity  protein binding  nucleus  cytoplasm  chloride transport  signal transduction  nuclear body  chloride channel complex  regulation of ion transmembrane transport  extracellular exosome  chloride transmembrane transport  
NDEx NetworkCLIC3
Atlas of Cancer Signalling NetworkCLIC3
Wikipedia pathwaysCLIC3
Orthology - Evolution
OrthoDB9022
GeneTree (enSembl)ENSG00000169583
Phylogenetic Trees/Animal Genes : TreeFamCLIC3
HOVERGENO95833
HOGENOMO95833
Homologs : HomoloGeneCLIC3
Homology/Alignments : Family Browser (UCSC)CLIC3
Gene fusions - Rearrangements
Tumor Fusion PortalCLIC3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLIC3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLIC3
dbVarCLIC3
ClinVarCLIC3
1000_GenomesCLIC3 
Exome Variant ServerCLIC3
ExAC (Exome Aggregation Consortium)ENSG00000169583
GNOMAD BrowserENSG00000169583
Genetic variants : HAPMAP9022
Genomic Variants (DGV)CLIC3 [DGVbeta]
DECIPHERCLIC3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLIC3 
Mutations
ICGC Data PortalCLIC3 
TCGA Data PortalCLIC3 
Broad Tumor PortalCLIC3
OASIS PortalCLIC3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLIC3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLIC3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLIC3
DgiDB (Drug Gene Interaction Database)CLIC3
DoCM (Curated mutations)CLIC3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLIC3 (select a term)
intoGenCLIC3
Cancer3DCLIC3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606533   
Orphanet
DisGeNETCLIC3
MedgenCLIC3
Genetic Testing Registry CLIC3
NextProtO95833 [Medical]
TSGene9022
GENETestsCLIC3
Target ValidationCLIC3
Huge Navigator CLIC3 [HugePedia]
snp3D : Map Gene to Disease9022
BioCentury BCIQCLIC3
ClinGenCLIC3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9022
Chemical/Pharm GKB GenePA26590
Clinical trialCLIC3
Miscellaneous
canSAR (ICR)CLIC3 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLIC3
EVEXCLIC3
GoPubMedCLIC3
iHOPCLIC3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:08:05 CET 2017

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