Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CLIC6 (chloride intracellular channel 6)

Identity

Alias_namesCLIC1L
Alias_symbol (synonym)CLIC5
Other alias
HGNC (Hugo) CLIC6
LocusID (NCBI) 54102
Atlas_Id 61887
Location 21q22.12  [Link to chromosome band 21q22]
Location_base_pair Starts at 36041688 and ends at 36090519 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CLIC6 (21q22.12) / ITSN1 (21q22.11)CLIC6 (21q22.12) / RPE65 (1p31.3)FOXJ3 (1p34.2) / CLIC6 (21q22.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLIC6   2065
Cards
Entrez_Gene (NCBI)CLIC6  54102  chloride intracellular channel 6
AliasesCLIC1L
GeneCards (Weizmann)CLIC6
Ensembl hg19 (Hinxton)ENSG00000159212 [Gene_View]  chr21:36041688-36090519 [Contig_View]  CLIC6 [Vega]
Ensembl hg38 (Hinxton)ENSG00000159212 [Gene_View]  chr21:36041688-36090519 [Contig_View]  CLIC6 [Vega]
ICGC DataPortalENSG00000159212
TCGA cBioPortalCLIC6
AceView (NCBI)CLIC6
Genatlas (Paris)CLIC6
WikiGenes54102
SOURCE (Princeton)CLIC6
Genetics Home Reference (NIH)CLIC6
Genomic and cartography
GoldenPath hg19 (UCSC)CLIC6  -     chr21:36041688-36090519 +  21q22.12   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CLIC6  -     21q22.12   [Description]    (hg38-Dec_2013)
EnsemblCLIC6 - 21q22.12 [CytoView hg19]  CLIC6 - 21q22.12 [CytoView hg38]
Mapping of homologs : NCBICLIC6 [Mapview hg19]  CLIC6 [Mapview hg38]
OMIM615321   
Gene and transcription
Genbank (Entrez)AF308293 AF426169 AF448438 AF448439 AK092733
RefSeq transcript (Entrez)NM_053277
RefSeq genomic (Entrez)NC_000021 NC_018932 NT_011512 NW_004929426
Consensus coding sequences : CCDS (NCBI)CLIC6
Cluster EST : UnigeneHs.473695 [ NCBI ]
CGAP (NCI)Hs.473695
Alternative Splicing GalleryENSG00000159212
Gene ExpressionCLIC6 [ NCBI-GEO ]   CLIC6 [ EBI - ARRAY_EXPRESS ]   CLIC6 [ SEEK ]   CLIC6 [ MEM ]
Gene Expression Viewer (FireBrowse)CLIC6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54102
GTEX Portal (Tissue expression)CLIC6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96NY7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96NY7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96NY7
Splice isoforms : SwissVarQ96NY7
PhosPhoSitePlusQ96NY7
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)   
Domains : Interpro (EBI)CLIC    CLIC-6    Glutathione-S-Trfase_C-like    Glutathione_S-Trfase_N    Thioredoxin-like_fold   
Domain families : Pfam (Sanger)GST_N_3 (PF13417)   
Domain families : Pfam (NCBI)pfam13417   
Conserved Domain (NCBI)CLIC6
DMDM Disease mutations54102
Blocks (Seattle)CLIC6
SuperfamilyQ96NY7
Human Protein AtlasENSG00000159212
Peptide AtlasQ96NY7
IPIIPI00394749   IPI00165936   
Protein Interaction databases
DIP (DOE-UCLA)Q96NY7
IntAct (EBI)Q96NY7
FunCoupENSG00000159212
BioGRIDCLIC6
STRING (EMBL)CLIC6
ZODIACCLIC6
Ontologies - Pathways
QuickGOQ96NY7
Ontology : AmiGOvoltage-gated ion channel activity  chloride channel activity  cytoplasm  plasma membrane  protein C-terminus binding  D2 dopamine receptor binding  D3 dopamine receptor binding  D4 dopamine receptor binding  chloride channel complex  regulation of ion transmembrane transport  protein homodimerization activity  extracellular exosome  chloride transmembrane transport  
Ontology : EGO-EBIvoltage-gated ion channel activity  chloride channel activity  cytoplasm  plasma membrane  protein C-terminus binding  D2 dopamine receptor binding  D3 dopamine receptor binding  D4 dopamine receptor binding  chloride channel complex  regulation of ion transmembrane transport  protein homodimerization activity  extracellular exosome  chloride transmembrane transport  
NDEx NetworkCLIC6
Atlas of Cancer Signalling NetworkCLIC6
Wikipedia pathwaysCLIC6
Orthology - Evolution
OrthoDB54102
GeneTree (enSembl)ENSG00000159212
Phylogenetic Trees/Animal Genes : TreeFamCLIC6
HOVERGENQ96NY7
HOGENOMQ96NY7
Homologs : HomoloGeneCLIC6
Homology/Alignments : Family Browser (UCSC)CLIC6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLIC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLIC6
dbVarCLIC6
ClinVarCLIC6
1000_GenomesCLIC6 
Exome Variant ServerCLIC6
ExAC (Exome Aggregation Consortium)CLIC6 (select the gene name)
Genetic variants : HAPMAP54102
Genomic Variants (DGV)CLIC6 [DGVbeta]
DECIPHER (Syndromes)21:36041688-36090519  ENSG00000159212
CONAN: Copy Number AnalysisCLIC6 
Mutations
ICGC Data PortalCLIC6 
TCGA Data PortalCLIC6 
Broad Tumor PortalCLIC6
OASIS PortalCLIC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLIC6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLIC6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLIC6
DgiDB (Drug Gene Interaction Database)CLIC6
DoCM (Curated mutations)CLIC6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLIC6 (select a term)
intoGenCLIC6
Cancer3DCLIC6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615321   
Orphanet
MedgenCLIC6
Genetic Testing Registry CLIC6
NextProtQ96NY7 [Medical]
TSGene54102
GENETestsCLIC6
Huge Navigator CLIC6 [HugePedia]
snp3D : Map Gene to Disease54102
BioCentury BCIQCLIC6
ClinGenCLIC6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54102
Chemical/Pharm GKB GenePA26593
Clinical trialCLIC6
Miscellaneous
canSAR (ICR)CLIC6 (select the gene name)
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLIC6
EVEXCLIC6
GoPubMedCLIC6
iHOPCLIC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 11:59:41 CET 2017

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