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CLIC6 (chloride intracellular channel 6)

Identity

Alias (NCBI)CLIC1L
HGNC (Hugo) CLIC6
HGNC Alias symbCLIC5
HGNC Previous nameCLIC1L
LocusID (NCBI) 54102
Atlas_Id 61887
Location 21q22.12  [Link to chromosome band 21q22]
Location_base_pair Starts at 34668994 and ends at 34718223 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLIC6 (21q22.12) / ITSN1 (21q22.11)CLIC6 (21q22.12) / RPE65 (1p31.3)FOXJ3 (1p34.2) / CLIC6 (21q22.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CLIC6   2065
Cards
Entrez_Gene (NCBI)CLIC6    chloride intracellular channel 6
AliasesCLIC1L
GeneCards (Weizmann)CLIC6
Ensembl hg19 (Hinxton)ENSG00000159212 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000159212 [Gene_View]  ENSG00000159212 [Sequence]  chr21:34668994-34718223 [Contig_View]  CLIC6 [Vega]
ICGC DataPortalENSG00000159212
TCGA cBioPortalCLIC6
AceView (NCBI)CLIC6
Genatlas (Paris)CLIC6
SOURCE (Princeton)CLIC6
Genetics Home Reference (NIH)CLIC6
Genomic and cartography
GoldenPath hg38 (UCSC)CLIC6  -     chr21:34668994-34718223 +  21q22.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLIC6  -     21q22.12   [Description]    (hg19-Feb_2009)
GoldenPathCLIC6 - 21q22.12 [CytoView hg19]  CLIC6 - 21q22.12 [CytoView hg38]
ImmunoBaseENSG00000159212
Genome Data Viewer NCBICLIC6 [Mapview hg19]  
OMIM615321   
Gene and transcription
Genbank (Entrez)AF308293 AF426169 AF448438 AF448439 AK092733
RefSeq transcript (Entrez)NM_001317009 NM_053277
Consensus coding sequences : CCDS (NCBI)CLIC6
Gene ExpressionCLIC6 [ NCBI-GEO ]   CLIC6 [ EBI - ARRAY_EXPRESS ]   CLIC6 [ SEEK ]   CLIC6 [ MEM ]
Gene Expression Viewer (FireBrowse)CLIC6 [ Firebrowse - Broad ]
GenevisibleExpression of CLIC6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54102
GTEX Portal (Tissue expression)CLIC6
Human Protein AtlasENSG00000159212-CLIC6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96NY7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96NY7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96NY7
PhosPhoSitePlusQ96NY7
Domaine pattern : Prosite (Expaxy)GST_CTER (PS50405)   
Domains : Interpro (EBI)CLIC    CLIC-4/6    Glutathione-S-Trfase_C-like    Glutathione-S-Trfase_C_sf    Glutathione_S-Trfase    Thioredoxin-like_sf   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)CLIC6
SuperfamilyQ96NY7
AlphaFold pdb e-kbQ96NY7   
Human Protein Atlas [tissue]ENSG00000159212-CLIC6 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q96NY7
IntAct (EBI)Q96NY7
BioGRIDCLIC6
STRING (EMBL)CLIC6
ZODIACCLIC6
Ontologies - Pathways
QuickGOQ96NY7
Ontology : AmiGOvoltage-gated ion channel activity  chloride channel activity  cytoplasm  plasma membrane  chloride transport  D2 dopamine receptor binding  D3 dopamine receptor binding  D4 dopamine receptor binding  ion transmembrane transport  chloride channel complex  regulation of ion transmembrane transport  extracellular exosome  
Ontology : EGO-EBIvoltage-gated ion channel activity  chloride channel activity  cytoplasm  plasma membrane  chloride transport  D2 dopamine receptor binding  D3 dopamine receptor binding  D4 dopamine receptor binding  ion transmembrane transport  chloride channel complex  regulation of ion transmembrane transport  extracellular exosome  
NDEx NetworkCLIC6
Atlas of Cancer Signalling NetworkCLIC6
Wikipedia pathwaysCLIC6
Orthology - Evolution
OrthoDB54102
GeneTree (enSembl)ENSG00000159212
Phylogenetic Trees/Animal Genes : TreeFamCLIC6
Homologs : HomoloGeneCLIC6
Homology/Alignments : Family Browser (UCSC)CLIC6
Gene fusions - Rearrangements
Fusion : QuiverCLIC6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLIC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLIC6
dbVarCLIC6
ClinVarCLIC6
MonarchCLIC6
1000_GenomesCLIC6 
Exome Variant ServerCLIC6
GNOMAD BrowserENSG00000159212
Varsome BrowserCLIC6
ACMGCLIC6 variants
VarityQ96NY7
Genomic Variants (DGV)CLIC6 [DGVbeta]
DECIPHERCLIC6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLIC6 
Mutations
ICGC Data PortalCLIC6 
TCGA Data PortalCLIC6 
Broad Tumor PortalCLIC6
OASIS PortalCLIC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLIC6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCLIC6
Mutations and Diseases : HGMDCLIC6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCLIC6
DgiDB (Drug Gene Interaction Database)CLIC6
DoCM (Curated mutations)CLIC6
CIViC (Clinical Interpretations of Variants in Cancer)CLIC6
Cancer3DCLIC6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615321   
Orphanet
DisGeNETCLIC6
MedgenCLIC6
Genetic Testing Registry CLIC6
NextProtQ96NY7 [Medical]
GENETestsCLIC6
Target ValidationCLIC6
Huge Navigator CLIC6 [HugePedia]
ClinGenCLIC6
Clinical trials, drugs, therapy
MyCancerGenomeCLIC6
Protein Interactions : CTDCLIC6
Pharm GKB GenePA26593
PharosQ96NY7
Clinical trialCLIC6
Miscellaneous
canSAR (ICR)CLIC6
HarmonizomeCLIC6
DataMed IndexCLIC6
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCLIC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:46:17 CEST 2021

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