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CLIP2 (CAP-Gly domain containing linker protein 2)

Identity

Alias (NCBI)CLIP
CLIP-115
CYLN2
WBSCR3
WBSCR4
WSCR3
WSCR4
HGNC (Hugo) CLIP2
HGNC Alias symbCLIP-115
KIAA0291
WSCR4
CLIP
WSCR3
HGNC Previous nameWBSCR4
 CYLN2
 WBSCR3
HGNC Previous namecytoplasmic linker 2
 Williams-Beuren syndrome chromosome region 3
 CAP-GLY domain containing linker protein 2
LocusID (NCBI) 7461
Atlas_Id 54218
Location 7q11.23  [Link to chromosome band 7q11]
Location_base_pair Starts at 74289407 and ends at 74405935 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CLIP2 (7q11.23) / KRT8 (12q13.13)CLIP2 (7q11.23) / PYGB (20p11.21)CLIP2 (7q11.23) / RFC2 (7q11.23)
ELL (19p13.11) / CLIP2 (7q11.23)ENG (9q34.11) / CLIP2 (7q11.23)FOXK2 (17q25.3) / CLIP2 (7q11.23)
GTF2I (7q11.23) / CLIP2 (7q11.23)KMT2C (7q36.1) / CLIP2 (7q11.23)MAPK1 (22q11.21) / CLIP2 (7q11.23)
SCGB3A1 (5q35.3) / CLIP2 (7q11.23)MLL3 CLIP2 7q11.23

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(7;17)(q11;q25) FOXK2/CLIP2


External links

Nomenclature
HGNC (Hugo)CLIP2   2586
Cards
Entrez_Gene (NCBI)CLIP2    CAP-Gly domain containing linker protein 2
AliasesCLIP; CLIP-115; CYLN2; WBSCR3; 
WBSCR4; WSCR3; WSCR4
GeneCards (Weizmann)CLIP2
Ensembl hg19 (Hinxton)ENSG00000106665 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000106665 [Gene_View]  ENSG00000106665 [Sequence]  chr7:74289407-74405935 [Contig_View]  CLIP2 [Vega]
ICGC DataPortalENSG00000106665
TCGA cBioPortalCLIP2
AceView (NCBI)CLIP2
Genatlas (Paris)CLIP2
SOURCE (Princeton)CLIP2
Genetics Home Reference (NIH)CLIP2
Genomic and cartography
GoldenPath hg38 (UCSC)CLIP2  -     chr7:74289407-74405935 +  7q11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLIP2  -     7q11.23   [Description]    (hg19-Feb_2009)
GoldenPathCLIP2 - 7q11.23 [CytoView hg19]  CLIP2 - 7q11.23 [CytoView hg38]
ImmunoBaseENSG00000106665
genome Data Viewer NCBICLIP2 [Mapview hg19]  
OMIM603432   
Gene and transcription
Genbank (Entrez)AB006629 AI204077 AL157546 AY295764 AY927468
RefSeq transcript (Entrez)NM_003388 NM_032421
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLIP2
Alternative Splicing GalleryENSG00000106665
Gene ExpressionCLIP2 [ NCBI-GEO ]   CLIP2 [ EBI - ARRAY_EXPRESS ]   CLIP2 [ SEEK ]   CLIP2 [ MEM ]
Gene Expression Viewer (FireBrowse)CLIP2 [ Firebrowse - Broad ]
GenevisibleExpression of CLIP2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7461
GTEX Portal (Tissue expression)CLIP2
Human Protein AtlasENSG00000106665-CLIP2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UDT6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UDT6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UDT6
Splice isoforms : SwissVarQ9UDT6
PhosPhoSitePlusQ9UDT6
Domaine pattern : Prosite (Expaxy)CAP_GLY_1 (PS00845)    CAP_GLY_2 (PS50245)   
Domains : Interpro (EBI)CAP-Gly_dom_sf    CAP-Gly_domain    CLIP2   
Domain families : Pfam (Sanger)CAP_GLY (PF01302)   
Domain families : Pfam (NCBI)pfam01302   
Domain families : Smart (EMBL)CAP_GLY (SM01052)  
Conserved Domain (NCBI)CLIP2
Blocks (Seattle)CLIP2
PDB (RSDB)2CP2    2CP3   
PDB Europe2CP2    2CP3   
PDB (PDBSum)2CP2    2CP3   
PDB (IMB)2CP2    2CP3   
Structural Biology KnowledgeBase2CP2    2CP3   
SCOP (Structural Classification of Proteins)2CP2    2CP3   
CATH (Classification of proteins structures)2CP2    2CP3   
SuperfamilyQ9UDT6
Human Protein Atlas [tissue]ENSG00000106665-CLIP2 [tissue]
Peptide AtlasQ9UDT6
HPRD09140
IPIIPI00019642   IPI00246616   IPI01010376   IPI01009924   IPI00946603   IPI00946773   
Protein Interaction databases
DIP (DOE-UCLA)Q9UDT6
IntAct (EBI)Q9UDT6
BioGRIDCLIP2
STRING (EMBL)CLIP2
ZODIACCLIP2
Ontologies - Pathways
QuickGOQ9UDT6
Ontology : AmiGOnucleus  cytoplasm  microtubule associated complex  microtubule binding  cytoplasmic microtubule organization  microtubule plus-end  microtubule plus-end  microtubule plus-end binding  
Ontology : EGO-EBInucleus  cytoplasm  microtubule associated complex  microtubule binding  cytoplasmic microtubule organization  microtubule plus-end  microtubule plus-end  microtubule plus-end binding  
NDEx NetworkCLIP2
Atlas of Cancer Signalling NetworkCLIP2
Wikipedia pathwaysCLIP2
Orthology - Evolution
OrthoDB7461
GeneTree (enSembl)ENSG00000106665
Phylogenetic Trees/Animal Genes : TreeFamCLIP2
HOGENOMQ9UDT6
Homologs : HomoloGeneCLIP2
Homology/Alignments : Family Browser (UCSC)CLIP2
Gene fusions - Rearrangements
Fusion : MitelmanELL/CLIP2 [19p13.11/7q11.23]  
Fusion : MitelmanGTF2I/CLIP2 [7q11.23/7q11.23]  
Fusion : MitelmanKMT2C/CLIP2 [7q36.1/7q11.23]  
Fusion PortalMLL3 CLIP2 7q11.23 BRCA
Fusion Cancer (Beijing)SCGB3A1 [5q35.3]  -  CLIP2 [7q11.23]  [FUSC002592]
Fusion : QuiverCLIP2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLIP2 [hg38]
dbVarCLIP2
ClinVarCLIP2
MonarchCLIP2
1000_GenomesCLIP2 
Exome Variant ServerCLIP2
GNOMAD BrowserENSG00000106665
Varsome BrowserCLIP2
Genomic Variants (DGV)CLIP2 [DGVbeta]
DECIPHERCLIP2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLIP2 
Mutations
ICGC Data PortalCLIP2 
TCGA Data PortalCLIP2 
Broad Tumor PortalCLIP2
OASIS PortalCLIP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLIP2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCLIP2
Mutations and Diseases : HGMDCLIP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLIP2
DgiDB (Drug Gene Interaction Database)CLIP2
DoCM (Curated mutations)CLIP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLIP2 (select a term)
intoGenCLIP2
Cancer3DCLIP2(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603432   
Orphanet145   
DisGeNETCLIP2
MedgenCLIP2
Genetic Testing Registry CLIP2
NextProtQ9UDT6 [Medical]
GENETestsCLIP2
Target ValidationCLIP2
Huge Navigator CLIP2 [HugePedia]
ClinGenCLIP2
Clinical trials, drugs, therapy
MyCancerGenomeCLIP2
Protein Interactions : CTD
Pharm GKB GenePA27085
PharosQ9UDT6
Clinical trialCLIP2
Miscellaneous
canSAR (ICR)CLIP2 (select the gene name)
HarmonizomeCLIP2
DataMed IndexCLIP2
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCLIP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Mar 25 19:16:00 CET 2021

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