CLMP (CXADR like membrane protein)

2013-06-01  

Identity

HGNC
LOCATION
11q24.1
LOCUSID
ALIAS
ACAM,ASAM,CSBM,CSBS
FUSION GENES

Other Information

Locus ID:

NCBI: 79827
MIM: 611693
HGNC: 24039
Ensembl: ENSG00000166250

Variants:

dbSNP: 79827
ClinVar: 79827
TCGA: ENSG00000166250
COSMIC: CLMP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000166250ENST00000448775Q9H6B4

Expression (GTEx)

0
50
100
150
200

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
145736222004CLMP, a novel member of the CTX family and a new component of epithelial tight junctions.25
221553682012CLMP is required for intestinal development, and loss-of-function mutations cause congenital short-bowel syndrome.14
227188162012The PDZ1 and PDZ3 domains of MAGI-1 regulate the eight-exon isoform of the coxsackievirus and adenovirus receptor.10
229928632012Coxsackievirus and adenovirus receptor promotes antitumor activity of oncolytic adenovirus H101 in esophageal cancer.10
155632742005Identification of adipocyte adhesion molecule (ACAM), a novel CTX gene family, implicated in adipocyte maturation and development of obesity.8
128517052003IGSF11 gene, frequently up-regulated in intestinal-type gastric cancer, encodes adhesion molecule homologous to CXADR, FLJ22415 and ESAM.7
273529672016Genetic screening of Congenital Short Bowel Syndrome patients confirms CLMP as the major gene involved in the recessive form of this disorder.5
234607812013CLMP is essential for intestinal development, but does not play a key role in cellular processes involved in intestinal epithelial development.4
277201792016Two new mutations of the CLMP gene identified in a newborn presenting congenital short-bowel syndrome.2

Citation

Dessen P

CLMP (CXADR like membrane protein)

Atlas Genet Cytogenet Oncol Haematol. 2013-06-01

Online version: http://atlasgeneticsoncology.org/gene/53366/clmp