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CLNK (cytokine dependent hematopoietic cell linker)

Identity

Alias_symbol (synonym)MIST
Other alias
HGNC (Hugo) CLNK
LocusID (NCBI) 116449
Atlas_Id 61897
Location 4p16.1  [Link to chromosome band 4p16]
Location_base_pair Starts at 10486405 and ends at 10684865 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
C1orf116 (1q32.1) / CLNK (4p16.1)CLNK (4p16.1) / CCT4 (2p15)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLNK   17438
Cards
Entrez_Gene (NCBI)CLNK  116449  cytokine dependent hematopoietic cell linker
AliasesMIST
GeneCards (Weizmann)CLNK
Ensembl hg19 (Hinxton)ENSG00000109684 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109684 [Gene_View]  chr4:10486405-10684865 [Contig_View]  CLNK [Vega]
ICGC DataPortalENSG00000109684
TCGA cBioPortalCLNK
AceView (NCBI)CLNK
Genatlas (Paris)CLNK
WikiGenes116449
SOURCE (Princeton)CLNK
Genetics Home Reference (NIH)CLNK
Genomic and cartography
GoldenPath hg38 (UCSC)CLNK  -     chr4:10486405-10684865 -  4p16.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLNK  -     4p16.1   [Description]    (hg19-Feb_2009)
EnsemblCLNK - 4p16.1 [CytoView hg19]  CLNK - 4p16.1 [CytoView hg38]
Mapping of homologs : NCBICLNK [Mapview hg19]  CLNK [Mapview hg38]
OMIM611434   
Gene and transcription
Genbank (Entrez)AB032369 AB110420 AK093001 BC029887 BC137553
RefSeq transcript (Entrez)NM_052964
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CLNK
Cluster EST : UnigeneHs.678910 [ NCBI ]
CGAP (NCI)Hs.678910
Alternative Splicing GalleryENSG00000109684
Gene ExpressionCLNK [ NCBI-GEO ]   CLNK [ EBI - ARRAY_EXPRESS ]   CLNK [ SEEK ]   CLNK [ MEM ]
Gene Expression Viewer (FireBrowse)CLNK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116449
GTEX Portal (Tissue expression)CLNK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z7G1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z7G1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z7G1
Splice isoforms : SwissVarQ7Z7G1
PhosPhoSitePlusQ7Z7G1
Domaine pattern : Prosite (Expaxy)SH2 (PS50001)   
Domains : Interpro (EBI)SH2   
Domain families : Pfam (Sanger)SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam00017   
Domain families : Smart (EMBL)SH2 (SM00252)  
Conserved Domain (NCBI)CLNK
DMDM Disease mutations116449
Blocks (Seattle)CLNK
SuperfamilyQ7Z7G1
Human Protein AtlasENSG00000109684
Peptide AtlasQ7Z7G1
HPRD14720
IPIIPI00185667   IPI00877744   IPI00879489   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z7G1
IntAct (EBI)Q7Z7G1
FunCoupENSG00000109684
BioGRIDCLNK
STRING (EMBL)CLNK
ZODIACCLNK
Ontologies - Pathways
QuickGOQ7Z7G1
Ontology : AmiGOSH3/SH2 adaptor activity  protein binding  intracellular  immune response  immune response  transmembrane receptor protein tyrosine kinase signaling pathway  positive regulation of signal transduction  intracellular signal transduction  
Ontology : EGO-EBISH3/SH2 adaptor activity  protein binding  intracellular  immune response  immune response  transmembrane receptor protein tyrosine kinase signaling pathway  positive regulation of signal transduction  intracellular signal transduction  
NDEx NetworkCLNK
Atlas of Cancer Signalling NetworkCLNK
Wikipedia pathwaysCLNK
Orthology - Evolution
OrthoDB116449
GeneTree (enSembl)ENSG00000109684
Phylogenetic Trees/Animal Genes : TreeFamCLNK
HOVERGENQ7Z7G1
HOGENOMQ7Z7G1
Homologs : HomoloGeneCLNK
Homology/Alignments : Family Browser (UCSC)CLNK
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLNK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLNK
dbVarCLNK
ClinVarCLNK
1000_GenomesCLNK 
Exome Variant ServerCLNK
ExAC (Exome Aggregation Consortium)CLNK (select the gene name)
Genetic variants : HAPMAP116449
Genomic Variants (DGV)CLNK [DGVbeta]
DECIPHERCLNK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLNK 
Mutations
ICGC Data PortalCLNK 
TCGA Data PortalCLNK 
Broad Tumor PortalCLNK
OASIS PortalCLNK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLNK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLNK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLNK
DgiDB (Drug Gene Interaction Database)CLNK
DoCM (Curated mutations)CLNK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLNK (select a term)
intoGenCLNK
Cancer3DCLNK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611434   
Orphanet
MedgenCLNK
Genetic Testing Registry CLNK
NextProtQ7Z7G1 [Medical]
TSGene116449
GENETestsCLNK
Huge Navigator CLNK [HugePedia]
snp3D : Map Gene to Disease116449
BioCentury BCIQCLNK
ClinGenCLNK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116449
Chemical/Pharm GKB GenePA164718067
Clinical trialCLNK
Miscellaneous
canSAR (ICR)CLNK (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLNK
EVEXCLNK
GoPubMedCLNK
iHOPCLNK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri May 19 11:06:12 CEST 2017

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