Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CLPX (caseinolytic mitochondrial matrix peptidase chaperone subunit)

Identity

Alias_namesClpX (caseinolytic protease X, E. coli) homolog
ClpX caseinolytic protease X homolog (E. coli)
ClpX caseinolytic peptidase X homolog (E. coli)
Other alias-
HGNC (Hugo) CLPX
LocusID (NCBI) 10845
Atlas_Id 55068
Location 15q22.31  [Link to chromosome band 15q22]
Location_base_pair Starts at 65440558 and ends at 65477758 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CLPX (15q22.31) / CLPX (15q22.31)CLPX (15q22.31) / IGDCC4 (15q22.31)CLPX 15q22.31 / IGDCC4 15q22.31

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLPX   2088
Cards
Entrez_Gene (NCBI)CLPX  10845  caseinolytic mitochondrial matrix peptidase chaperone subunit
Aliases
GeneCards (Weizmann)CLPX
Ensembl hg19 (Hinxton)ENSG00000166855 [Gene_View]  chr15:65440558-65477758 [Contig_View]  CLPX [Vega]
Ensembl hg38 (Hinxton)ENSG00000166855 [Gene_View]  chr15:65440558-65477758 [Contig_View]  CLPX [Vega]
ICGC DataPortalENSG00000166855
TCGA cBioPortalCLPX
AceView (NCBI)CLPX
Genatlas (Paris)CLPX
WikiGenes10845
SOURCE (Princeton)CLPX
Genetics Home Reference (NIH)CLPX
Genomic and cartography
GoldenPath hg19 (UCSC)CLPX  -     chr15:65440558-65477758 -  15q22.31   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CLPX  -     15q22.31   [Description]    (hg38-Dec_2013)
EnsemblCLPX - 15q22.31 [CytoView hg19]  CLPX - 15q22.31 [CytoView hg38]
Mapping of homologs : NCBICLPX [Mapview hg19]  CLPX [Mapview hg38]
OMIM615611   
Gene and transcription
Genbank (Entrez)AJ006267 AK292316 AK308133 AK310614 AL136922
RefSeq transcript (Entrez)NM_006660
RefSeq genomic (Entrez)NC_000015 NC_018926 NT_010194 NW_004929398
Consensus coding sequences : CCDS (NCBI)CLPX
Cluster EST : UnigeneHs.113823 [ NCBI ]
CGAP (NCI)Hs.113823
Alternative Splicing GalleryENSG00000166855
Gene ExpressionCLPX [ NCBI-GEO ]   CLPX [ EBI - ARRAY_EXPRESS ]   CLPX [ SEEK ]   CLPX [ MEM ]
Gene Expression Viewer (FireBrowse)CLPX [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10845
GTEX Portal (Tissue expression)CLPX
Protein : pattern, domain, 3D structure
UniProt/SwissProtO76031   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO76031  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO76031
Splice isoforms : SwissVarO76031
PhosPhoSitePlusO76031
Domains : Interpro (EBI)AAA+_ATPase    ATPase_AAA_core    Clp_ATPase_C    Clp_protease_ATP-bd_su_ClpX    P-loop_NTPase   
Domain families : Pfam (Sanger)AAA_2 (PF07724)    ClpB_D2-small (PF10431)   
Domain families : Pfam (NCBI)pfam07724    pfam10431   
Domain families : Smart (EMBL)AAA (SM00382)  ClpB_D2-small (SM01086)  
Conserved Domain (NCBI)CLPX
DMDM Disease mutations10845
Blocks (Seattle)CLPX
SuperfamilyO76031
Human Protein AtlasENSG00000166855
Peptide AtlasO76031
HPRD07478
IPIIPI00008728   IPI01012768   
Protein Interaction databases
DIP (DOE-UCLA)O76031
IntAct (EBI)O76031
FunCoupENSG00000166855
BioGRIDCLPX
STRING (EMBL)CLPX
ZODIACCLPX
Ontologies - Pathways
QuickGOO76031
Ontology : AmiGOATP-dependent peptidase activity  protein binding  ATP binding  ATP binding  nucleoplasm  cytoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial matrix  protein folding  endopeptidase Clp complex  mitochondrial endopeptidase Clp complex  positive regulation of peptidase activity  peptidase activator activity  ATPase activity  ATPase activity  mitochondrial nucleoid  metal ion binding  unfolded protein binding  proteolysis involved in cellular protein catabolic process  
Ontology : EGO-EBIATP-dependent peptidase activity  protein binding  ATP binding  ATP binding  nucleoplasm  cytoplasm  mitochondrion  mitochondrial inner membrane  mitochondrial matrix  protein folding  endopeptidase Clp complex  mitochondrial endopeptidase Clp complex  positive regulation of peptidase activity  peptidase activator activity  ATPase activity  ATPase activity  mitochondrial nucleoid  metal ion binding  unfolded protein binding  proteolysis involved in cellular protein catabolic process  
NDEx NetworkCLPX
Atlas of Cancer Signalling NetworkCLPX
Wikipedia pathwaysCLPX
Orthology - Evolution
OrthoDB10845
GeneTree (enSembl)ENSG00000166855
Phylogenetic Trees/Animal Genes : TreeFamCLPX
HOVERGENO76031
HOGENOMO76031
Homologs : HomoloGeneCLPX
Homology/Alignments : Family Browser (UCSC)CLPX
Gene fusions - Rearrangements
Fusion : MitelmanCLPX/IGDCC4 [15q22.31/15q22.31]  
Fusion: TCGACLPX 15q22.31 IGDCC4 15q22.31 PRAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLPX [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLPX
dbVarCLPX
ClinVarCLPX
1000_GenomesCLPX 
Exome Variant ServerCLPX
ExAC (Exome Aggregation Consortium)CLPX (select the gene name)
Genetic variants : HAPMAP10845
Genomic Variants (DGV)CLPX [DGVbeta]
DECIPHER (Syndromes)15:65440558-65477758  ENSG00000166855
CONAN: Copy Number AnalysisCLPX 
Mutations
ICGC Data PortalCLPX 
TCGA Data PortalCLPX 
Broad Tumor PortalCLPX
OASIS PortalCLPX [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLPX  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLPX
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch CLPX
DgiDB (Drug Gene Interaction Database)CLPX
DoCM (Curated mutations)CLPX (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLPX (select a term)
intoGenCLPX
Cancer3DCLPX(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615611   
Orphanet
MedgenCLPX
Genetic Testing Registry CLPX
NextProtO76031 [Medical]
TSGene10845
GENETestsCLPX
Huge Navigator CLPX [HugePedia]
snp3D : Map Gene to Disease10845
BioCentury BCIQCLPX
ClinGenCLPX
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10845
Chemical/Pharm GKB GenePA26614
Clinical trialCLPX
Miscellaneous
canSAR (ICR)CLPX (select the gene name)
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLPX
EVEXCLPX
GoPubMedCLPX
iHOPCLPX
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 13:00:55 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.