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CLTA (clathrin light chain A)

Identity

Alias_namesclathrin, light polypeptide (Lca)
clathrin, light chain A
Alias_symbol (synonym)Lca
Other aliasLCA
HGNC (Hugo) CLTA
LocusID (NCBI) 1211
Atlas_Id 52431
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 36190853 and ends at 36212059 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
BCL10 (1p22.3) / CLTA (9p13.3)CLTA (9p13.3) / ALK (2p23.2)CLTA (9p13.3) / ATP9A (20q13.2)
CLTA (9p13.3) / CLTA (9p13.3)CLTA (9p13.3) / MTPN (7q33)CLTA (9p13.3) / UBE2R2 (9p13.3)
UQCRH (1p34.1) / CLTA (9p13.3)CLTA 9p13.3 / UBE2R2 9p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CLTA   2090
Cards
Entrez_Gene (NCBI)CLTA  1211  clathrin light chain A
AliasesLCA
GeneCards (Weizmann)CLTA
Ensembl hg19 (Hinxton)ENSG00000122705 [Gene_View]  chr9:36190853-36212059 [Contig_View]  CLTA [Vega]
Ensembl hg38 (Hinxton)ENSG00000122705 [Gene_View]  chr9:36190853-36212059 [Contig_View]  CLTA [Vega]
ICGC DataPortalENSG00000122705
TCGA cBioPortalCLTA
AceView (NCBI)CLTA
Genatlas (Paris)CLTA
WikiGenes1211
SOURCE (Princeton)CLTA
Genetics Home Reference (NIH)CLTA
Genomic and cartography
GoldenPath hg19 (UCSC)CLTA  -     chr9:36190853-36212059 +  9p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CLTA  -     9p13.3   [Description]    (hg38-Dec_2013)
EnsemblCLTA - 9p13.3 [CytoView hg19]  CLTA - 9p13.3 [CytoView hg38]
Mapping of homologs : NCBICLTA [Mapview hg19]  CLTA [Mapview hg38]
OMIM118960   
Gene and transcription
Genbank (Entrez)AK225153 AK291078 AK295692 BC009201 BC019287
RefSeq transcript (Entrez)NM_001076677 NM_001184760 NM_001184761 NM_001184762 NM_001311203 NM_001311204 NM_001311205 NM_001311206 NM_001833 NM_007096
RefSeq genomic (Entrez)NC_000009 NC_018920 NT_008413 NW_004929342
Consensus coding sequences : CCDS (NCBI)CLTA
Cluster EST : UnigeneHs.522114 [ NCBI ]
CGAP (NCI)Hs.522114
Alternative Splicing GalleryENSG00000122705
Gene ExpressionCLTA [ NCBI-GEO ]   CLTA [ EBI - ARRAY_EXPRESS ]   CLTA [ SEEK ]   CLTA [ MEM ]
Gene Expression Viewer (FireBrowse)CLTA [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1211
GTEX Portal (Tissue expression)CLTA
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09496   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09496  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09496
Splice isoforms : SwissVarP09496
PhosPhoSitePlusP09496
Domaine pattern : Prosite (Expaxy)CLATHRIN_LIGHT_CHN_1 (PS00224)    CLATHRIN_LIGHT_CHN_2 (PS00581)   
Domains : Interpro (EBI)Clathrin_L-chain   
Domain families : Pfam (Sanger)Clathrin_lg_ch (PF01086)   
Domain families : Pfam (NCBI)pfam01086   
Conserved Domain (NCBI)CLTA
DMDM Disease mutations1211
Blocks (Seattle)CLTA
SuperfamilyP09496
Human Protein AtlasENSG00000122705
Peptide AtlasP09496
HPRD00351
IPIIPI00014587   IPI00216393   IPI00790571   IPI00979352   IPI00977178   IPI00945731   IPI00946844   IPI00945895   IPI00945566   
Protein Interaction databases
DIP (DOE-UCLA)P09496
IntAct (EBI)P09496
FunCoupENSG00000122705
BioGRIDCLTA
STRING (EMBL)CLTA
ZODIACCLTA
Ontologies - Pathways
QuickGOP09496
Ontology : AmiGOmolecular_function  structural molecule activity  protein binding  cytosol  plasma membrane  intracellular protein transport  microtubule-based movement  membrane  cytoplasmic, membrane-bounded vesicle  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin coat  clathrin vesicle coat  clathrin coat of trans-Golgi network vesicle  clathrin coat of coated pit  clathrin heavy chain binding  trans-Golgi network membrane  endolysosome membrane  negative regulation of epidermal growth factor receptor signaling pathway  peptide binding  intracellular membrane-bounded organelle  clathrin complex  clathrin-mediated endocytosis  
Ontology : EGO-EBImolecular_function  structural molecule activity  protein binding  cytosol  plasma membrane  intracellular protein transport  microtubule-based movement  membrane  cytoplasmic, membrane-bounded vesicle  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin coat  clathrin vesicle coat  clathrin coat of trans-Golgi network vesicle  clathrin coat of coated pit  clathrin heavy chain binding  trans-Golgi network membrane  endolysosome membrane  negative regulation of epidermal growth factor receptor signaling pathway  peptide binding  intracellular membrane-bounded organelle  clathrin complex  clathrin-mediated endocytosis  
Pathways : KEGGLysosome    Endocytosis    Synaptic vesicle cycle    Endocrine and other factor-regulated calcium reabsorption    Huntington's disease    Bacterial invasion of epithelial cells   
NDEx NetworkCLTA
Atlas of Cancer Signalling NetworkCLTA
Wikipedia pathwaysCLTA
Orthology - Evolution
OrthoDB1211
GeneTree (enSembl)ENSG00000122705
Phylogenetic Trees/Animal Genes : TreeFamCLTA
HOVERGENP09496
HOGENOMP09496
Homologs : HomoloGeneCLTA
Homology/Alignments : Family Browser (UCSC)CLTA
Gene fusions - Rearrangements
Fusion : MitelmanCLTA/UBE2R2 [9p13.3/9p13.3]  
Fusion: TCGACLTA 9p13.3 UBE2R2 9p13.3 GBM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLTA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLTA
dbVarCLTA
ClinVarCLTA
1000_GenomesCLTA 
Exome Variant ServerCLTA
ExAC (Exome Aggregation Consortium)CLTA (select the gene name)
Genetic variants : HAPMAP1211
Genomic Variants (DGV)CLTA [DGVbeta]
DECIPHER (Syndromes)9:36190853-36212059  ENSG00000122705
CONAN: Copy Number AnalysisCLTA 
Mutations
ICGC Data PortalCLTA 
TCGA Data PortalCLTA 
Broad Tumor PortalCLTA
OASIS PortalCLTA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLTA  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCLTA
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CLTA
DgiDB (Drug Gene Interaction Database)CLTA
DoCM (Curated mutations)CLTA (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CLTA (select a term)
intoGenCLTA
Cancer3DCLTA(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118960   
Orphanet
MedgenCLTA
Genetic Testing Registry CLTA
NextProtP09496 [Medical]
TSGene1211
GENETestsCLTA
Huge Navigator CLTA [HugePedia]
snp3D : Map Gene to Disease1211
BioCentury BCIQCLTA
ClinGenCLTA
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1211
Chemical/Pharm GKB GenePA26616
Clinical trialCLTA
Miscellaneous
canSAR (ICR)CLTA (select the gene name)
Probes
Litterature
PubMed64 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCLTA
EVEXCLTA
GoPubMedCLTA
iHOPCLTA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:56:55 CEST 2017

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