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CLTA (clathrin light chain A)

Identity

Alias (NCBI)LCA
HGNC (Hugo) CLTA
HGNC Alias symbLca
HGNC Previous nameclathrin, light polypeptide (Lca)
 clathrin, light chain A
LocusID (NCBI) 1211
Atlas_Id 52431
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 36190921 and ends at 36212059 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BCL10 (1p22.3) / CLTA (9p13.3)CLTA (9p13.3) / ALK (2p23.2)CLTA (9p13.3) / ATP9A (20q13.2)
CLTA (9p13.3) / CLTA (9p13.3)CLTA (9p13.3) / MTPN (7q33)CLTA (9p13.3) / UBE2R2 (9p13.3)
UQCRH (1p34.1) / CLTA (9p13.3)CLTA 9p13.3 / UBE2R2 9p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CLTA   2090
Cards
Entrez_Gene (NCBI)CLTA    clathrin light chain A
AliasesLCA
GeneCards (Weizmann)CLTA
Ensembl hg19 (Hinxton)ENSG00000122705 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000122705 [Gene_View]  ENSG00000122705 [Sequence]  chr9:36190921-36212059 [Contig_View]  CLTA [Vega]
ICGC DataPortalENSG00000122705
TCGA cBioPortalCLTA
AceView (NCBI)CLTA
Genatlas (Paris)CLTA
SOURCE (Princeton)CLTA
Genetics Home Reference (NIH)CLTA
Genomic and cartography
GoldenPath hg38 (UCSC)CLTA  -     chr9:36190921-36212059 +  9p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CLTA  -     9p13.3   [Description]    (hg19-Feb_2009)
GoldenPathCLTA - 9p13.3 [CytoView hg19]  CLTA - 9p13.3 [CytoView hg38]
ImmunoBaseENSG00000122705
Genome Data Viewer NCBICLTA [Mapview hg19]  
OMIM118960   
Gene and transcription
Genbank (Entrez)AK225153 AK291078 AK295692 BC009201 BC019287
RefSeq transcript (Entrez)NM_001076677 NM_001184760 NM_001184761 NM_001184762 NM_001311203 NM_001311204 NM_001311205 NM_001311206 NM_001833 NM_007096
Consensus coding sequences : CCDS (NCBI)CLTA
Gene ExpressionCLTA [ NCBI-GEO ]   CLTA [ EBI - ARRAY_EXPRESS ]   CLTA [ SEEK ]   CLTA [ MEM ]
Gene Expression Viewer (FireBrowse)CLTA [ Firebrowse - Broad ]
GenevisibleExpression of CLTA in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1211
GTEX Portal (Tissue expression)CLTA
Human Protein AtlasENSG00000122705-CLTA [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP09496   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP09496  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP09496
PhosPhoSitePlusP09496
Domaine pattern : Prosite (Expaxy)CLATHRIN_LIGHT_CHN_1 (PS00224)    CLATHRIN_LIGHT_CHN_2 (PS00581)   
Domains : Interpro (EBI)Clathrin_L-chain   
Domain families : Pfam (Sanger)Clathrin_lg_ch (PF01086)   
Domain families : Pfam (NCBI)pfam01086   
Conserved Domain (NCBI)CLTA
PDB (RSDB)6E5N   
PDB Europe6E5N   
PDB (PDBSum)6E5N   
PDB (IMB)6E5N   
Structural Biology KnowledgeBase6E5N   
SCOP (Structural Classification of Proteins)6E5N   
CATH (Classification of proteins structures)6E5N   
SuperfamilyP09496
AlphaFold pdb e-kbP09496   
Human Protein Atlas [tissue]ENSG00000122705-CLTA [tissue]
HPRD00351
Protein Interaction databases
DIP (DOE-UCLA)P09496
IntAct (EBI)P09496
BioGRIDCLTA
STRING (EMBL)CLTA
ZODIACCLTA
Ontologies - Pathways
QuickGOP09496
Ontology : AmiGOmolecular_function  structural molecule activity  protein binding  spindle  cytosol  plasma membrane  plasma membrane  intracellular protein transport  post-Golgi vesicle-mediated transport  cell cycle  membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin coat  clathrin coat  clathrin vesicle coat  clathrin coat of trans-Golgi network vesicle  clathrin coat of coated pit  synaptic vesicle membrane  cytoplasmic vesicle  clathrin heavy chain binding  clathrin heavy chain binding  trans-Golgi network membrane  low-density lipoprotein particle receptor catabolic process  low-density lipoprotein particle clearance  endolysosome membrane  peptide binding  protein-containing complex binding  clathrin-coated endocytic vesicle  clathrin coat assembly  clathrin coat assembly  GTPase binding  cell division  membrane organization  clathrin complex  clathrin-dependent endocytosis  presynaptic endocytic zone membrane  postsynaptic endocytic zone cytoplasmic component  
Ontology : EGO-EBImolecular_function  structural molecule activity  protein binding  spindle  cytosol  plasma membrane  plasma membrane  intracellular protein transport  post-Golgi vesicle-mediated transport  cell cycle  membrane  antigen processing and presentation of exogenous peptide antigen via MHC class II  clathrin coat  clathrin coat  clathrin vesicle coat  clathrin coat of trans-Golgi network vesicle  clathrin coat of coated pit  synaptic vesicle membrane  cytoplasmic vesicle  clathrin heavy chain binding  clathrin heavy chain binding  trans-Golgi network membrane  low-density lipoprotein particle receptor catabolic process  low-density lipoprotein particle clearance  endolysosome membrane  peptide binding  protein-containing complex binding  clathrin-coated endocytic vesicle  clathrin coat assembly  clathrin coat assembly  GTPase binding  cell division  membrane organization  clathrin complex  clathrin-dependent endocytosis  presynaptic endocytic zone membrane  postsynaptic endocytic zone cytoplasmic component  
Pathways : KEGGLysosome    Endocytosis    Synaptic vesicle cycle    Endocrine and other factor-regulated calcium reabsorption    Huntington's disease    Bacterial invasion of epithelial cells   
NDEx NetworkCLTA
Atlas of Cancer Signalling NetworkCLTA
Wikipedia pathwaysCLTA
Orthology - Evolution
OrthoDB1211
GeneTree (enSembl)ENSG00000122705
Phylogenetic Trees/Animal Genes : TreeFamCLTA
Homologs : HomoloGeneCLTA
Homology/Alignments : Family Browser (UCSC)CLTA
Gene fusions - Rearrangements
Fusion : MitelmanCLTA/UBE2R2 [9p13.3/9p13.3]  
Fusion : QuiverCLTA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCLTA [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CLTA
dbVarCLTA
ClinVarCLTA
MonarchCLTA
1000_GenomesCLTA 
Exome Variant ServerCLTA
GNOMAD BrowserENSG00000122705
Varsome BrowserCLTA
ACMGCLTA variants
VarityP09496
Genomic Variants (DGV)CLTA [DGVbeta]
DECIPHERCLTA [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCLTA 
Mutations
ICGC Data PortalCLTA 
TCGA Data PortalCLTA 
Broad Tumor PortalCLTA
OASIS PortalCLTA [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCLTA  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCLTA
Mutations and Diseases : HGMDCLTA
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCLTA
DgiDB (Drug Gene Interaction Database)CLTA
DoCM (Curated mutations)CLTA
CIViC (Clinical Interpretations of Variants in Cancer)CLTA
Cancer3DCLTA
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM118960   
Orphanet
DisGeNETCLTA
MedgenCLTA
Genetic Testing Registry CLTA
NextProtP09496 [Medical]
GENETestsCLTA
Target ValidationCLTA
Huge Navigator CLTA [HugePedia]
ClinGenCLTA
Clinical trials, drugs, therapy
MyCancerGenomeCLTA
Protein Interactions : CTDCLTA
Pharm GKB GenePA26616
PharosP09496
Clinical trialCLTA
Miscellaneous
canSAR (ICR)CLTA
HarmonizomeCLTA
DataMed IndexCLTA
Probes
Litterature
PubMed96 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCLTA
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Oct 4 15:04:25 CEST 2021

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