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CMBL (carboxymethylenebutenolidase homolog (Pseudomonas))

Identity

Alias_namescarboxymethylenebutenolidase-like (Pseudomonas)
carboxymethylenebutenolidase homolog (Pseudomonas)
Alias_symbol (synonym)FLJ23617
Other aliasJS-1
HGNC (Hugo) CMBL
LocusID (NCBI) 134147
Atlas_Id 54220
Location 5p15.2  [Link to chromosome band 5p15]
Location_base_pair Starts at 10277707 and ends at 10308168 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CMBL (5p15.2) / AATF (17q12)CMBL (5p15.2) / DARS2 (1q25.1)CMBL (5p15.2) / DCAF8 (1q23.2)
CMBL (5p15.2) / FAM76A (1p35.3)CMBL (5p15.2) / NDUFAF6 (8q22.1)DENR (12q24.31) / CMBL (5p15.2)
CMBL 5p15.2 / DARS2 1q25.1

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  Lung: Translocations in Adenocarcinoma


External links

Nomenclature
HGNC (Hugo)CMBL   25090
Cards
Entrez_Gene (NCBI)CMBL  134147  carboxymethylenebutenolidase homolog (Pseudomonas)
AliasesJS-1
GeneCards (Weizmann)CMBL
Ensembl hg19 (Hinxton)ENSG00000164237 [Gene_View]  chr5:10277707-10308168 [Contig_View]  CMBL [Vega]
Ensembl hg38 (Hinxton)ENSG00000164237 [Gene_View]  chr5:10277707-10308168 [Contig_View]  CMBL [Vega]
ICGC DataPortalENSG00000164237
TCGA cBioPortalCMBL
AceView (NCBI)CMBL
Genatlas (Paris)CMBL
WikiGenes134147
SOURCE (Princeton)CMBL
Genetics Home Reference (NIH)CMBL
Genomic and cartography
GoldenPath hg19 (UCSC)CMBL  -     chr5:10277707-10308168 -  5p15.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CMBL  -     5p15.2   [Description]    (hg38-Dec_2013)
EnsemblCMBL - 5p15.2 [CytoView hg19]  CMBL - 5p15.2 [CytoView hg38]
Mapping of homologs : NCBICMBL [Mapview hg19]  CMBL [Mapview hg38]
OMIM613379   
Gene and transcription
Genbank (Entrez)AJ278125 AK074197 AK315390 BC001573 BX647141
RefSeq transcript (Entrez)NM_138809
RefSeq genomic (Entrez)NC_000005 NC_018916 NT_006576 NW_004929321
Consensus coding sequences : CCDS (NCBI)CMBL
Cluster EST : UnigeneHs.192586 [ NCBI ]
CGAP (NCI)Hs.192586
Alternative Splicing GalleryENSG00000164237
Gene ExpressionCMBL [ NCBI-GEO ]   CMBL [ EBI - ARRAY_EXPRESS ]   CMBL [ SEEK ]   CMBL [ MEM ]
Gene Expression Viewer (FireBrowse)CMBL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)134147
GTEX Portal (Tissue expression)CMBL
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96DG6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96DG6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96DG6
Splice isoforms : SwissVarQ96DG6
PhosPhoSitePlusQ96DG6
Domains : Interpro (EBI)AB_hydrolase    Dienelactn_hydro   
Domain families : Pfam (Sanger)DLH (PF01738)   
Domain families : Pfam (NCBI)pfam01738   
Conserved Domain (NCBI)CMBL
DMDM Disease mutations134147
Blocks (Seattle)CMBL
SuperfamilyQ96DG6
Human Protein AtlasENSG00000164237
Peptide AtlasQ96DG6
HPRD14055
IPIIPI00383046   
Protein Interaction databases
DIP (DOE-UCLA)Q96DG6
IntAct (EBI)Q96DG6
FunCoupENSG00000164237
BioGRIDCMBL
STRING (EMBL)CMBL
ZODIACCMBL
Ontologies - Pathways
QuickGOQ96DG6
Ontology : AmiGOcytosol  xenobiotic metabolic process  hydrolase activity  extracellular exosome  
Ontology : EGO-EBIcytosol  xenobiotic metabolic process  hydrolase activity  extracellular exosome  
NDEx NetworkCMBL
Atlas of Cancer Signalling NetworkCMBL
Wikipedia pathwaysCMBL
Orthology - Evolution
OrthoDB134147
GeneTree (enSembl)ENSG00000164237
Phylogenetic Trees/Animal Genes : TreeFamCMBL
HOVERGENQ96DG6
HOGENOMQ96DG6
Homologs : HomoloGeneCMBL
Homology/Alignments : Family Browser (UCSC)CMBL
Gene fusions - Rearrangements
Fusion : MitelmanCMBL/DARS2 [5p15.2/1q25.1]  
Fusion : MitelmanCMBL/NDUFAF6 [5p15.2/8q22.1]  [t(5;8)(p15;q22)]  
Fusion: TCGACMBL 5p15.2 DARS2 1q25.1 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCMBL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CMBL
dbVarCMBL
ClinVarCMBL
1000_GenomesCMBL 
Exome Variant ServerCMBL
ExAC (Exome Aggregation Consortium)CMBL (select the gene name)
Genetic variants : HAPMAP134147
Genomic Variants (DGV)CMBL [DGVbeta]
DECIPHER (Syndromes)5:10277707-10308168  ENSG00000164237
CONAN: Copy Number AnalysisCMBL 
Mutations
ICGC Data PortalCMBL 
TCGA Data PortalCMBL 
Broad Tumor PortalCMBL
OASIS PortalCMBL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCMBL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCMBL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CMBL
DgiDB (Drug Gene Interaction Database)CMBL
DoCM (Curated mutations)CMBL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CMBL (select a term)
intoGenCMBL
Cancer3DCMBL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613379   
Orphanet
MedgenCMBL
Genetic Testing Registry CMBL
NextProtQ96DG6 [Medical]
TSGene134147
GENETestsCMBL
Huge Navigator CMBL [HugePedia]
snp3D : Map Gene to Disease134147
BioCentury BCIQCMBL
ClinGenCMBL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD134147
Chemical/Pharm GKB GenePA162382521
Clinical trialCMBL
Miscellaneous
canSAR (ICR)CMBL (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCMBL
EVEXCMBL
GoPubMedCMBL
iHOPCMBL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:56:57 CEST 2017

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