CMTM6 (CKLF like MARVEL transmembrane domain containing 6)

2018-02-01  

Identity

HGNC
LOCATION
3p22.3
LOCUSID
ALIAS
CKLFSF6,PRO2219
FUSION GENES

Other Information

Locus ID:

NCBI: 54918
MIM: 607889
HGNC: 19177
Ensembl: ENSG00000091317

Variants:

dbSNP: 54918
ClinVar: 54918
TCGA: ENSG00000091317
COSMIC: CMTM6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000091317ENST00000205636Q9NX76

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
288134172017CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity.87
288134102017Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.76
127821302003Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation.31
301313082018CMTM6 overexpression is associated with molecular and clinical characteristics of malignancy and predicts poor prognosis in gliomas.8
305620632019Expression and Clinical Significance of CMTM6 in Hepatocellular Carcinoma.5

Citation

Dessen P

CMTM6 (CKLF like MARVEL transmembrane domain containing 6)

Atlas Genet Cytogenet Oncol Haematol. 2018-02-01

Online version: http://atlasgeneticsoncology.org/gene/57316/cmtm6