Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

CMTR1 (cap methyltransferase 1)

Identity

Alias_namesKIAA0082
FTSJD2
KIAA0082
FtsJ methyltransferase domain containing 2
Alias_symbol (synonym)MTr1
ISG95
Other aliashMTr1
HGNC (Hugo) CMTR1
LocusID (NCBI) 23070
Atlas_Id 54223
Location 6p21.2  [Link to chromosome band 6p21]
Location_base_pair Starts at 37433131 and ends at 37481508 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CMTR1 (6p21.2) / GPX6 (6p22.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(p21;p22) CMTR1/GPX6


External links

Nomenclature
HGNC (Hugo)CMTR1   21077
Cards
Entrez_Gene (NCBI)CMTR1  23070  cap methyltransferase 1
AliasesFTSJD2; KIAA0082; MTr1; hMTr1
GeneCards (Weizmann)CMTR1
Ensembl hg19 (Hinxton)ENSG00000137200 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137200 [Gene_View]  ENSG00000137200 [Sequence]  chr6:37433131-37481508 [Contig_View]  CMTR1 [Vega]
ICGC DataPortalENSG00000137200
TCGA cBioPortalCMTR1
AceView (NCBI)CMTR1
Genatlas (Paris)CMTR1
WikiGenes23070
SOURCE (Princeton)CMTR1
Genetics Home Reference (NIH)CMTR1
Genomic and cartography
GoldenPath hg38 (UCSC)CMTR1  -     chr6:37433131-37481508 +  6p21.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CMTR1  -     6p21.2   [Description]    (hg19-Feb_2009)
EnsemblCMTR1 - 6p21.2 [CytoView hg19]  CMTR1 - 6p21.2 [CytoView hg38]
Mapping of homologs : NCBICMTR1 [Mapview hg19]  CMTR1 [Mapview hg38]
OMIM616189   
Gene and transcription
Genbank (Entrez)AK000348 AK025809 AK124393 AK292564 BC010731
RefSeq transcript (Entrez)NM_015050
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CMTR1
Cluster EST : UnigeneHs.520102 [ NCBI ]
CGAP (NCI)Hs.520102
Alternative Splicing GalleryENSG00000137200
Gene ExpressionCMTR1 [ NCBI-GEO ]   CMTR1 [ EBI - ARRAY_EXPRESS ]   CMTR1 [ SEEK ]   CMTR1 [ MEM ]
Gene Expression Viewer (FireBrowse)CMTR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23070
GTEX Portal (Tissue expression)CMTR1
Human Protein AtlasENSG00000137200-CMTR1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N1G2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N1G2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N1G2
Splice isoforms : SwissVarQ8N1G2
PhosPhoSitePlusQ8N1G2
Domaine pattern : Prosite (Expaxy)G_PATCH (PS50174)    SAM_MT_RRMJ (PS51613)    WW_DOMAIN_1 (PS01159)   
Domains : Interpro (EBI)Cap_mRNA_MeTrfase_1    G_patch_dom    RrmJ-type_MeTrfase    rRNA_MeTrfase_FtsJ_dom    SAM-dependent_MTases    WW_dom   
Domain families : Pfam (Sanger)FtsJ (PF01728)    G-patch (PF01585)   
Domain families : Pfam (NCBI)pfam01728    pfam01585   
Domain families : Smart (EMBL)G_patch (SM00443)  WW (SM00456)  
Conserved Domain (NCBI)CMTR1
DMDM Disease mutations23070
Blocks (Seattle)CMTR1
PDB (SRS)4N48    4N49    4N4A   
PDB (PDBSum)4N48    4N49    4N4A   
PDB (IMB)4N48    4N49    4N4A   
PDB (RSDB)4N48    4N49    4N4A   
Structural Biology KnowledgeBase4N48    4N49    4N4A   
SCOP (Structural Classification of Proteins)4N48    4N49    4N4A   
CATH (Classification of proteins structures)4N48    4N49    4N4A   
SuperfamilyQ8N1G2
Human Protein Atlas [tissue]ENSG00000137200-CMTR1 [tissue]
Peptide AtlasQ8N1G2
HPRD08305
IPIIPI00166153   IPI00514387   IPI00514843   IPI00976641   IPI00514419   
Protein Interaction databases
DIP (DOE-UCLA)Q8N1G2
IntAct (EBI)Q8N1G2
FunCoupENSG00000137200
BioGRIDCMTR1
STRING (EMBL)CMTR1
ZODIACCMTR1
Ontologies - Pathways
QuickGOQ8N1G2
Ontology : AmiGOnucleic acid binding  mRNA (nucleoside-2'-O-)-methyltransferase activity  mRNA (nucleoside-2'-O-)-methyltransferase activity  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  7-methylguanosine mRNA capping  7-methylguanosine mRNA capping  7-methylguanosine mRNA capping  mRNA methylation  cap1 mRNA methylation  cap1 mRNA methylation  
Ontology : EGO-EBInucleic acid binding  mRNA (nucleoside-2'-O-)-methyltransferase activity  mRNA (nucleoside-2'-O-)-methyltransferase activity  nucleus  nucleus  nucleoplasm  cytoplasm  cytosol  7-methylguanosine mRNA capping  7-methylguanosine mRNA capping  7-methylguanosine mRNA capping  mRNA methylation  cap1 mRNA methylation  cap1 mRNA methylation  
NDEx NetworkCMTR1
Atlas of Cancer Signalling NetworkCMTR1
Wikipedia pathwaysCMTR1
Orthology - Evolution
OrthoDB23070
GeneTree (enSembl)ENSG00000137200
Phylogenetic Trees/Animal Genes : TreeFamCMTR1
HOVERGENQ8N1G2
HOGENOMQ8N1G2
Homologs : HomoloGeneCMTR1
Homology/Alignments : Family Browser (UCSC)CMTR1
Gene fusions - Rearrangements
Fusion : MitelmanCMTR1/GPX6 [6p21.2/6p22.1]  
Fusion : QuiverCMTR1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCMTR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CMTR1
dbVarCMTR1
ClinVarCMTR1
1000_GenomesCMTR1 
Exome Variant ServerCMTR1
ExAC (Exome Aggregation Consortium)ENSG00000137200
GNOMAD BrowserENSG00000137200
Varsome BrowserCMTR1
Genetic variants : HAPMAP23070
Genomic Variants (DGV)CMTR1 [DGVbeta]
DECIPHERCMTR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCMTR1 
Mutations
ICGC Data PortalCMTR1 
TCGA Data PortalCMTR1 
Broad Tumor PortalCMTR1
OASIS PortalCMTR1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDCMTR1
BioMutasearch CMTR1
DgiDB (Drug Gene Interaction Database)CMTR1
DoCM (Curated mutations)CMTR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CMTR1 (select a term)
intoGenCMTR1
Cancer3DCMTR1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616189   
Orphanet
DisGeNETCMTR1
MedgenCMTR1
Genetic Testing Registry CMTR1
NextProtQ8N1G2 [Medical]
TSGene23070
GENETestsCMTR1
Target ValidationCMTR1
Huge Navigator CMTR1 [HugePedia]
snp3D : Map Gene to Disease23070
BioCentury BCIQCMTR1
ClinGenCMTR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23070
Chemical/Pharm GKB GenePA162389052
Clinical trialCMTR1
Miscellaneous
canSAR (ICR)CMTR1 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCMTR1
EVEXCMTR1
GoPubMedCMTR1
iHOPCMTR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 10:59:05 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.