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CNBP (CCHC-type zinc finger nucleic acid binding protein)

Identity

Alias_namesDM2
ZNF9
zinc finger protein 9 (a cellular retroviral nucleic acid binding protein)
zinc finger protein 9
CCHC-type zinc finger, nucleic acid binding protein
Alias_symbol (synonym)RNF163
ZCCHC22
CNBP1
Other aliasPROMM
HGNC (Hugo) CNBP
LocusID (NCBI) 7555
Atlas_Id 42961
Location 3q21.3  [Link to chromosome band 3q21]
Location_base_pair Starts at 129167815 and ends at 129183967 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATP1A3 (19q13.2) / CNBP (3q21.3)CNBP (3q21.3) / ALDH1L1 (3q21.3)CNBP (3q21.3) / CSNK2A1 (20p13)
CNBP (3q21.3) / EIF4H (7q11.23)CNBP (3q21.3) / FBL (19q13.2)CNBP (3q21.3) / USP6 (17p13.2)
NAP1L4 (11p15.4) / CNBP (3q21.3)TAF15 (17q12) / CNBP (3q21.3)USP6 (17p13.2) / CNBP (3q21.3)
CNBP 3q21.3 / USP6 17p13.2CNBP 3q21.3 / ALDH1L1 3q21.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Protein

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  Bone: Aneurysmal bone cysts
Bone: Aneurysmal bone cyst with t(3;17)(q21;p13) CNBP/USP6


External links

Nomenclature
HGNC (Hugo)CNBP   13164
Cards
Entrez_Gene (NCBI)CNBP  7555  CCHC-type zinc finger nucleic acid binding protein
AliasesCNBP1; DM2; PROMM; RNF163; 
ZCCHC22; ZNF9
GeneCards (Weizmann)CNBP
Ensembl hg19 (Hinxton)ENSG00000169714 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000169714 [Gene_View]  chr3:129167815-129183967 [Contig_View]  CNBP [Vega]
ICGC DataPortalENSG00000169714
TCGA cBioPortalCNBP
AceView (NCBI)CNBP
Genatlas (Paris)CNBP
WikiGenes7555
SOURCE (Princeton)CNBP
Genetics Home Reference (NIH)CNBP
Genomic and cartography
GoldenPath hg38 (UCSC)CNBP  -     chr3:129167815-129183967 -  3q21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CNBP  -     3q21.3   [Description]    (hg19-Feb_2009)
EnsemblCNBP - 3q21.3 [CytoView hg19]  CNBP - 3q21.3 [CytoView hg38]
Mapping of homologs : NCBICNBP [Mapview hg19]  CNBP [Mapview hg38]
OMIM116955   602668   
Gene and transcription
Genbank (Entrez)AK021693 AK054592 AK292119 AK298154 AK314380
RefSeq transcript (Entrez)NM_001127192 NM_001127193 NM_001127194 NM_001127195 NM_001127196 NM_003418
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CNBP
Cluster EST : UnigeneHs.518249 [ NCBI ]
CGAP (NCI)Hs.518249
Alternative Splicing GalleryENSG00000169714
Gene ExpressionCNBP [ NCBI-GEO ]   CNBP [ EBI - ARRAY_EXPRESS ]   CNBP [ SEEK ]   CNBP [ MEM ]
Gene Expression Viewer (FireBrowse)CNBP [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)7555
GTEX Portal (Tissue expression)CNBP
Protein : pattern, domain, 3D structure
UniProt/SwissProtP62633   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP62633  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP62633
Splice isoforms : SwissVarP62633
PhosPhoSitePlusP62633
Domaine pattern : Prosite (Expaxy)ZF_CCHC (PS50158)   
Domains : Interpro (EBI)Znf_CCHC   
Domain families : Pfam (Sanger)zf-CCHC (PF00098)   
Domain families : Pfam (NCBI)pfam00098   
Domain families : Smart (EMBL)ZnF_C2HC (SM00343)  
Conserved Domain (NCBI)CNBP
DMDM Disease mutations7555
Blocks (Seattle)CNBP
SuperfamilyP62633
Human Protein AtlasENSG00000169714
Peptide AtlasP62633
HPRD00311
IPIIPI00430812   IPI00430813   IPI00430814   IPI00895852   IPI00977873   IPI00965541   IPI00895911   IPI00967344   IPI00895806   
Protein Interaction databases
DIP (DOE-UCLA)P62633
IntAct (EBI)P62633
FunCoupENSG00000169714
BioGRIDCNBP
STRING (EMBL)CNBP
ZODIACCNBP
Ontologies - Pathways
QuickGOP62633
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  single-stranded DNA binding  transcription factor activity, sequence-specific DNA binding  RNA binding  single-stranded RNA binding  protein binding  nucleus  nucleus  endoplasmic reticulum  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  cholesterol biosynthetic process  zinc ion binding  positive regulation of cell proliferation  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  RNA polymerase II regulatory region sequence-specific DNA binding  transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding  single-stranded DNA binding  transcription factor activity, sequence-specific DNA binding  RNA binding  single-stranded RNA binding  protein binding  nucleus  nucleus  endoplasmic reticulum  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  cholesterol biosynthetic process  zinc ion binding  positive regulation of cell proliferation  positive regulation of transcription, DNA-templated  positive regulation of transcription from RNA polymerase II promoter  
NDEx NetworkCNBP
Atlas of Cancer Signalling NetworkCNBP
Wikipedia pathwaysCNBP
Orthology - Evolution
OrthoDB7555
GeneTree (enSembl)ENSG00000169714
Phylogenetic Trees/Animal Genes : TreeFamCNBP
HOVERGENP62633
HOGENOMP62633
Homologs : HomoloGeneCNBP
Homology/Alignments : Family Browser (UCSC)CNBP
Gene fusions - Rearrangements
Fusion : MitelmanCNBP/ALDH1L1 [3q21.3/3q21.3]  
Fusion : MitelmanCNBP/USP6 [3q21.3/17p13.2]  [t(3;7)(q21;p13)]  
Fusion: TCGACNBP 3q21.3 ALDH1L1 3q21.3 LGG
Fusion Cancer (Beijing)TAF15 [17q12]  -  CNBP [3q21.3]  [FUSC003802]
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNBP [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNBP
dbVarCNBP
ClinVarCNBP
1000_GenomesCNBP 
Exome Variant ServerCNBP
ExAC (Exome Aggregation Consortium)CNBP (select the gene name)
Genetic variants : HAPMAP7555
Genomic Variants (DGV)CNBP [DGVbeta]
DECIPHERCNBP [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCNBP 
Mutations
ICGC Data PortalCNBP 
TCGA Data PortalCNBP 
Broad Tumor PortalCNBP
OASIS PortalCNBP [ Somatic mutations - Copy number]
Cancer Gene: CensusCNBP 
Somatic Mutations in Cancer : COSMICCNBP  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCNBP
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CNBP
DgiDB (Drug Gene Interaction Database)CNBP
DoCM (Curated mutations)CNBP (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CNBP (select a term)
intoGenCNBP
Cancer3DCNBP(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM116955    602668   
Orphanet545   
MedgenCNBP
Genetic Testing Registry CNBP
NextProtP62633 [Medical]
TSGene7555
GENETestsCNBP
Target ValidationCNBP
Huge Navigator CNBP [HugePedia]
snp3D : Map Gene to Disease7555
BioCentury BCIQCNBP
ClinGenCNBP
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD7555
Chemical/Pharm GKB GenePA37737
Clinical trialCNBP
Miscellaneous
canSAR (ICR)CNBP (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCNBP
EVEXCNBP
GoPubMedCNBP
iHOPCNBP
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:28:54 CEST 2017

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