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CNKSR3 (CNKSR family member 3)

Identity

Alias_namesMAGI1
membrane associated guanylate kinase interacting protein-like 1
Alias_symbol (synonym)FLJ31349
Other aliasCNK3
HGNC (Hugo) CNKSR3
LocusID (NCBI) 154043
Atlas_Id 61940
Location 6q25.2  [Link to chromosome band 6q25]
Location_base_pair Starts at 154405299 and ends at 154510659 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
CNKSR3 (6q25.2) / CNKSR3 (6q25.2)CNKSR3 (6q25.2) / GDE1 (16p12.3)CNKSR3 (6q25.2) / RABGAP1L (1q25.1)
CNKSR3 (6q25.2) / SBSN (19q13.12)EPC2 (2q23.1) / CNKSR3 (6q25.2)MAP7 (6q23.3) / CNKSR3 (6q25.2)
UST (6q25.1) / CNKSR3 (6q25.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(q23;q25) MAP7/CNKSR3


External links

Nomenclature
HGNC (Hugo)CNKSR3   23034
Cards
Entrez_Gene (NCBI)CNKSR3  154043  CNKSR family member 3
AliasesCNK3; MAGI1
GeneCards (Weizmann)CNKSR3
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]   [Sequence]  chr6:154405299-154510659 [Contig_View]  CNKSR3 [Vega]
TCGA cBioPortalCNKSR3
AceView (NCBI)CNKSR3
Genatlas (Paris)CNKSR3
WikiGenes154043
SOURCE (Princeton)CNKSR3
Genetics Home Reference (NIH)CNKSR3
Genomic and cartography
GoldenPath hg38 (UCSC)CNKSR3  -     chr6:154405299-154510659 -  6q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CNKSR3  -     6q25.2   [Description]    (hg19-Feb_2009)
EnsemblCNKSR3 - 6q25.2 [CytoView hg19]  CNKSR3 - 6q25.2 [CytoView hg38]
Mapping of homologs : NCBICNKSR3 [Mapview hg19]  CNKSR3 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK055911 AK309680 AY328891 AY328892 AY328893
RefSeq transcript (Entrez)NM_173515
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CNKSR3
Cluster EST : UnigeneHs.16064 [ NCBI ]
CGAP (NCI)Hs.16064
Gene ExpressionCNKSR3 [ NCBI-GEO ]   CNKSR3 [ EBI - ARRAY_EXPRESS ]   CNKSR3 [ SEEK ]   CNKSR3 [ MEM ]
Gene Expression Viewer (FireBrowse)CNKSR3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)154043
GTEX Portal (Tissue expression)CNKSR3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6P9H4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6P9H4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6P9H4
Splice isoforms : SwissVarQ6P9H4
PhosPhoSitePlusQ6P9H4
Domaine pattern : Prosite (Expaxy)CRIC (PS51290)    PDZ (PS50106)    SAM_DOMAIN (PS50105)   
Domains : Interpro (EBI)CNKSR2    CRIC_domain    PDZ    SAM    SAM/pointed   
Domain families : Pfam (Sanger)CRIC_ras_sig (PF10534)    DUF1170 (PF06663)    PDZ (PF00595)    SAM_1 (PF00536)   
Domain families : Pfam (NCBI)pfam10534    pfam06663    pfam00595    pfam00536   
Domain families : Smart (EMBL)PDZ (SM00228)  SAM (SM00454)  
Conserved Domain (NCBI)CNKSR3
DMDM Disease mutations154043
Blocks (Seattle)CNKSR3
SuperfamilyQ6P9H4
Peptide AtlasQ6P9H4
HPRD14349
IPIIPI00411298   IPI00515049   IPI00514513   IPI00940748   IPI00944970   
Protein Interaction databases
DIP (DOE-UCLA)Q6P9H4
IntAct (EBI)Q6P9H4
BioGRIDCNKSR3
STRING (EMBL)CNKSR3
ZODIACCNKSR3
Ontologies - Pathways
QuickGOQ6P9H4
Ontology : AmiGOprotein binding  cytoplasm  positive regulation of sodium ion transport  membrane  negative regulation of peptidyl-serine phosphorylation  negative regulation of ERK1 and ERK2 cascade  
Ontology : EGO-EBIprotein binding  cytoplasm  positive regulation of sodium ion transport  membrane  negative regulation of peptidyl-serine phosphorylation  negative regulation of ERK1 and ERK2 cascade  
NDEx NetworkCNKSR3
Atlas of Cancer Signalling NetworkCNKSR3
Wikipedia pathwaysCNKSR3
Orthology - Evolution
OrthoDB154043
Phylogenetic Trees/Animal Genes : TreeFamCNKSR3
HOVERGENQ6P9H4
HOGENOMQ6P9H4
Homologs : HomoloGeneCNKSR3
Homology/Alignments : Family Browser (UCSC)CNKSR3
Gene fusions - Rearrangements
Fusion : QuiverCNKSR3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNKSR3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNKSR3
dbVarCNKSR3
ClinVarCNKSR3
1000_GenomesCNKSR3 
Exome Variant ServerCNKSR3
Varsome BrowserCNKSR3
Genetic variants : HAPMAP154043
Genomic Variants (DGV)CNKSR3 [DGVbeta]
DECIPHERCNKSR3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCNKSR3 
Mutations
ICGC Data PortalCNKSR3 
TCGA Data PortalCNKSR3 
Broad Tumor PortalCNKSR3
OASIS PortalCNKSR3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCNKSR3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCNKSR3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CNKSR3
DgiDB (Drug Gene Interaction Database)CNKSR3
DoCM (Curated mutations)CNKSR3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CNKSR3 (select a term)
intoGenCNKSR3
Cancer3DCNKSR3(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETCNKSR3
MedgenCNKSR3
Genetic Testing Registry CNKSR3
NextProtQ6P9H4 [Medical]
TSGene154043
GENETestsCNKSR3
Target ValidationCNKSR3
Huge Navigator CNKSR3 [HugePedia]
snp3D : Map Gene to Disease154043
BioCentury BCIQCNKSR3
ClinGenCNKSR3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD154043
Chemical/Pharm GKB GenePA134880153
Clinical trialCNKSR3
Miscellaneous
canSAR (ICR)CNKSR3 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCNKSR3
EVEXCNKSR3
GoPubMedCNKSR3
iHOPCNKSR3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Jul 30 13:41:00 CEST 2018

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