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CNN2 (calponin 2)

Identity

Other alias-
HGNC (Hugo) CNN2
LocusID (NCBI) 1265
Atlas_Id 55186
Location 19p13.3  [Link to chromosome band 19p13]
Location_base_pair Starts at 1026274 and ends at 1039067 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CNN2 (19p13.3) / C2CD4C (19p13.3)CNN2 (19p13.3) / FBXO15 (18q22.3)CNN2 (19p13.3) / MED16 (19p13.3)
CNN2 (19p13.3) / SSU72 (1p36.33)CNN2 (19p13.3) / WAC (10p12.1)FCAR (19q13.42) / CNN2 (19p13.3)
KDSR (18q21.33) / CNN2 (19p13.3)PIK3C2A (11p15.1) / CNN2 (19p13.3)CNN2 19p13.3 / C2CD4C 19p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CNN2   2156
Cards
Entrez_Gene (NCBI)CNN2  1265  calponin 2
Aliases
GeneCards (Weizmann)CNN2
Ensembl hg19 (Hinxton)ENSG00000064666 [Gene_View]  chr19:1026274-1039067 [Contig_View]  CNN2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000064666 [Gene_View]  chr19:1026274-1039067 [Contig_View]  CNN2 [Vega]
ICGC DataPortalENSG00000064666
TCGA cBioPortalCNN2
AceView (NCBI)CNN2
Genatlas (Paris)CNN2
WikiGenes1265
SOURCE (Princeton)CNN2
Genetics Home Reference (NIH)CNN2
Genomic and cartography
GoldenPath hg19 (UCSC)CNN2  -     chr19:1026274-1039067 +  19p13.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)CNN2  -     19p13.3   [Description]    (hg38-Dec_2013)
EnsemblCNN2 - 19p13.3 [CytoView hg19]  CNN2 - 19p13.3 [CytoView hg38]
Mapping of homologs : NCBICNN2 [Mapview hg19]  CNN2 [Mapview hg38]
OMIM602373   
Gene and transcription
Genbank (Entrez)AA283126 AK024835 AK057960 AK093630 AK126391
RefSeq transcript (Entrez)NM_001303499 NM_001303501 NM_004368 NM_201277
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011295 NW_004929412
Consensus coding sequences : CCDS (NCBI)CNN2
Cluster EST : UnigeneHs.651512 [ NCBI ]
CGAP (NCI)Hs.651512
Alternative Splicing GalleryENSG00000064666
Gene ExpressionCNN2 [ NCBI-GEO ]   CNN2 [ EBI - ARRAY_EXPRESS ]   CNN2 [ SEEK ]   CNN2 [ MEM ]
Gene Expression Viewer (FireBrowse)CNN2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1265
GTEX Portal (Tissue expression)CNN2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99439   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99439  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99439
Splice isoforms : SwissVarQ99439
PhosPhoSitePlusQ99439
Domaine pattern : Prosite (Expaxy)CALPONIN_1 (PS01052)    CALPONIN_2 (PS51122)    CH (PS50021)   
Domains : Interpro (EBI)Calponin/LIMCH1    Calponin_repeat    CH-domain    CNN2    SM22_calponin   
Domain families : Pfam (Sanger)Calponin (PF00402)    CH (PF00307)   
Domain families : Pfam (NCBI)pfam00402    pfam00307   
Domain families : Smart (EMBL)CH (SM00033)  
Conserved Domain (NCBI)CNN2
DMDM Disease mutations1265
Blocks (Seattle)CNN2
PDB (SRS)1WYN   
PDB (PDBSum)1WYN   
PDB (IMB)1WYN   
PDB (RSDB)1WYN   
Structural Biology KnowledgeBase1WYN   
SCOP (Structural Classification of Proteins)1WYN   
CATH (Classification of proteins structures)1WYN   
SuperfamilyQ99439
Human Protein AtlasENSG00000064666
Peptide AtlasQ99439
HPRD03847
IPIIPI00015262   IPI00910272   IPI00910593   IPI00398735   
Protein Interaction databases
DIP (DOE-UCLA)Q99439
IntAct (EBI)Q99439
FunCoupENSG00000064666
BioGRIDCNN2
STRING (EMBL)CNN2
ZODIACCNN2
Ontologies - Pathways
QuickGOQ99439
Ontology : AmiGOstress fiber  actin binding  calmodulin binding  cytoskeleton  cell-cell junction  focal adhesion  cytoskeleton organization  membrane  actomyosin structure organization  regulation of actin filament-based process  extracellular exosome  cellular response to mechanical stimulus  
Ontology : EGO-EBIstress fiber  actin binding  calmodulin binding  cytoskeleton  cell-cell junction  focal adhesion  cytoskeleton organization  membrane  actomyosin structure organization  regulation of actin filament-based process  extracellular exosome  cellular response to mechanical stimulus  
NDEx NetworkCNN2
Atlas of Cancer Signalling NetworkCNN2
Wikipedia pathwaysCNN2
Orthology - Evolution
OrthoDB1265
GeneTree (enSembl)ENSG00000064666
Phylogenetic Trees/Animal Genes : TreeFamCNN2
HOVERGENQ99439
HOGENOMQ99439
Homologs : HomoloGeneCNN2
Homology/Alignments : Family Browser (UCSC)CNN2
Gene fusions - Rearrangements
Fusion : MitelmanCNN2/C2CD4C [19p13.3/19p13.3]  
Fusion: TCGACNN2 19p13.3 C2CD4C 19p13.3 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNN2
dbVarCNN2
ClinVarCNN2
1000_GenomesCNN2 
Exome Variant ServerCNN2
ExAC (Exome Aggregation Consortium)CNN2 (select the gene name)
Genetic variants : HAPMAP1265
Genomic Variants (DGV)CNN2 [DGVbeta]
DECIPHER (Syndromes)19:1026274-1039067  ENSG00000064666
CONAN: Copy Number AnalysisCNN2 
Mutations
ICGC Data PortalCNN2 
TCGA Data PortalCNN2 
Broad Tumor PortalCNN2
OASIS PortalCNN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCNN2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCNN2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CNN2
DgiDB (Drug Gene Interaction Database)CNN2
DoCM (Curated mutations)CNN2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CNN2 (select a term)
intoGenCNN2
Cancer3DCNN2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602373   
Orphanet
MedgenCNN2
Genetic Testing Registry CNN2
NextProtQ99439 [Medical]
TSGene1265
GENETestsCNN2
Huge Navigator CNN2 [HugePedia]
snp3D : Map Gene to Disease1265
BioCentury BCIQCNN2
ClinGenCNN2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1265
Chemical/Pharm GKB GenePA26666
Clinical trialCNN2
Miscellaneous
canSAR (ICR)CNN2 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCNN2
EVEXCNN2
GoPubMedCNN2
iHOPCNN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:57:02 CEST 2017

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