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CNN3 (calponin 3)

Identity

Alias_namescalponin 3
Other alias-
HGNC (Hugo) CNN3
LocusID (NCBI) 1266
Atlas_Id 50569
Location 1p21.3  [Link to chromosome band 1p21]
Location_base_pair Starts at 94896949 and ends at 94927223 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CNN3 (1p21.3) / ALG14 (1p21.3)CNN3 (1p21.3) / CACHD1 (1p31.3)CNN3 (1p21.3) / CNN3 (1p21.3)
IGH (14q32.33) / CNN3 (1p21.3)IGHG1 (14q32.33) / CNN3 (1p21.3)CNN3 1p21.3 / ALG14 1p21.3
CNN3 1p21.3 / CACHD1 1p31.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CNN3   2157
Cards
Entrez_Gene (NCBI)CNN3  1266  calponin 3
Aliases
GeneCards (Weizmann)CNN3
Ensembl hg19 (Hinxton)ENSG00000117519 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000117519 [Gene_View]  chr1:94896949-94927223 [Contig_View]  CNN3 [Vega]
ICGC DataPortalENSG00000117519
TCGA cBioPortalCNN3
AceView (NCBI)CNN3
Genatlas (Paris)CNN3
WikiGenes1266
SOURCE (Princeton)CNN3
Genetics Home Reference (NIH)CNN3
Genomic and cartography
GoldenPath hg38 (UCSC)CNN3  -     chr1:94896949-94927223 -  1p21.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CNN3  -     1p21.3   [Description]    (hg19-Feb_2009)
EnsemblCNN3 - 1p21.3 [CytoView hg19]  CNN3 - 1p21.3 [CytoView hg38]
Mapping of homologs : NCBICNN3 [Mapview hg19]  CNN3 [Mapview hg38]
OMIM602374   
Gene and transcription
Genbank (Entrez)AK294141 AK298145 AK312370 AK316398 BC025372
RefSeq transcript (Entrez)NM_001286055 NM_001286056 NM_001839
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CNN3
Cluster EST : UnigeneHs.736112 [ NCBI ]
CGAP (NCI)Hs.736112
Alternative Splicing GalleryENSG00000117519
Gene ExpressionCNN3 [ NCBI-GEO ]   CNN3 [ EBI - ARRAY_EXPRESS ]   CNN3 [ SEEK ]   CNN3 [ MEM ]
Gene Expression Viewer (FireBrowse)CNN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1266
GTEX Portal (Tissue expression)CNN3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ15417   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ15417  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ15417
Splice isoforms : SwissVarQ15417
PhosPhoSitePlusQ15417
Domaine pattern : Prosite (Expaxy)CALPONIN_1 (PS01052)    CALPONIN_2 (PS51122)    CH (PS50021)   
Domains : Interpro (EBI)Calponin/LIMCH1    Calponin_repeat    CH-domain    SM22_calponin   
Domain families : Pfam (Sanger)Calponin (PF00402)    CH (PF00307)   
Domain families : Pfam (NCBI)pfam00402    pfam00307   
Domain families : Smart (EMBL)CH (SM00033)  
Conserved Domain (NCBI)CNN3
DMDM Disease mutations1266
Blocks (Seattle)CNN3
SuperfamilyQ15417
Human Protein AtlasENSG00000117519
Peptide AtlasQ15417
HPRD03848
IPIIPI00216682   IPI00642542   IPI00909623   
Protein Interaction databases
DIP (DOE-UCLA)Q15417
IntAct (EBI)Q15417
FunCoupENSG00000117519
BioGRIDCNN3
STRING (EMBL)CNN3
ZODIACCNN3
Ontologies - Pathways
QuickGOQ15417
Ontology : AmiGOactin binding  calmodulin binding  cytosol  cell-cell adherens junction  focal adhesion  microtubule binding  postsynaptic density  actin cytoskeleton  epithelial cell differentiation  actomyosin structure organization  negative regulation of ATPase activity  neuronal cell body  dendritic spine  cell-cell adhesion  cadherin binding involved in cell-cell adhesion  
Ontology : EGO-EBIactin binding  calmodulin binding  cytosol  cell-cell adherens junction  focal adhesion  microtubule binding  postsynaptic density  actin cytoskeleton  epithelial cell differentiation  actomyosin structure organization  negative regulation of ATPase activity  neuronal cell body  dendritic spine  cell-cell adhesion  cadherin binding involved in cell-cell adhesion  
NDEx NetworkCNN3
Atlas of Cancer Signalling NetworkCNN3
Wikipedia pathwaysCNN3
Orthology - Evolution
OrthoDB1266
GeneTree (enSembl)ENSG00000117519
Phylogenetic Trees/Animal Genes : TreeFamCNN3
HOVERGENQ15417
HOGENOMQ15417
Homologs : HomoloGeneCNN3
Homology/Alignments : Family Browser (UCSC)CNN3
Gene fusions - Rearrangements
Fusion : MitelmanCNN3/ALG14 [1p21.3/1p21.3]  
Fusion : MitelmanCNN3/CACHD1 [1p21.3/1p31.3]  [t(1;1)(p21;p31)]  
Fusion : MitelmanIGH/CNN3 [14q32.33/1p21.3]  [t(1;14)(p21;q32)]  
Fusion: TCGACNN3 1p21.3 ALG14 1p21.3 GBM
Fusion: TCGACNN3 1p21.3 CACHD1 1p31.3 SKCM
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNN3
dbVarCNN3
ClinVarCNN3
1000_GenomesCNN3 
Exome Variant ServerCNN3
ExAC (Exome Aggregation Consortium)CNN3 (select the gene name)
Genetic variants : HAPMAP1266
Genomic Variants (DGV)CNN3 [DGVbeta]
DECIPHERCNN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCNN3 
Mutations
ICGC Data PortalCNN3 
TCGA Data PortalCNN3 
Broad Tumor PortalCNN3
OASIS PortalCNN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCNN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCNN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CNN3
DgiDB (Drug Gene Interaction Database)CNN3
DoCM (Curated mutations)CNN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CNN3 (select a term)
intoGenCNN3
Cancer3DCNN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602374   
Orphanet
MedgenCNN3
Genetic Testing Registry CNN3
NextProtQ15417 [Medical]
TSGene1266
GENETestsCNN3
Target ValidationCNN3
Huge Navigator CNN3 [HugePedia]
snp3D : Map Gene to Disease1266
BioCentury BCIQCNN3
ClinGenCNN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1266
Chemical/Pharm GKB GenePA26667
Clinical trialCNN3
Miscellaneous
canSAR (ICR)CNN3 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCNN3
EVEXCNN3
GoPubMedCNN3
iHOPCNN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:28:57 CEST 2017

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