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CNNM2 (cyclin and CBS domain divalent metal cation transport mediator 2)

Identity

Alias (NCBI)ACDP2
HOMG6
HOMGSMR
HGNC (Hugo) CNNM2
HGNC Previous nameACDP2
HGNC Previous namecyclin M2
LocusID (NCBI) 54805
Atlas_Id 61943
Location 10q24.32  [Link to chromosome band 10q24]
Location_base_pair Starts at 102918318 and ends at 102927618 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
BOLA2 (16p11.2) / CNNM2 (10q24.32)CNNM2 (10q24.32) / NOTCH4 (6p21.32)CNNM2 (10q24.32) / SUFU (10q24.32)
TPM4 (19p13.12) / CNNM2 (10q24.32)CNNM2 SUFUCNNM2 NOTCH4

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CNNM2   103
Cards
Entrez_Gene (NCBI)CNNM2    cyclin and CBS domain divalent metal cation transport mediator 2
AliasesACDP2; HOMG6; HOMGSMR
GeneCards (Weizmann)CNNM2
Ensembl hg19 (Hinxton)ENSG00000148842 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148842 [Gene_View]  ENSG00000148842 [Sequence]  chr10:102918318-102927618 [Contig_View]  CNNM2 [Vega]
ICGC DataPortalENSG00000148842
TCGA cBioPortalCNNM2
AceView (NCBI)CNNM2
Genatlas (Paris)CNNM2
SOURCE (Princeton)CNNM2
Genetics Home Reference (NIH)CNNM2
Genomic and cartography
GoldenPath hg38 (UCSC)CNNM2  -     chr10:102918318-102927618 +  10q24.32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CNNM2  -     10q24.32   [Description]    (hg19-Feb_2009)
GoldenPathCNNM2 - 10q24.32 [CytoView hg19]  CNNM2 - 10q24.32 [CytoView hg38]
ImmunoBaseENSG00000148842
Genome Data Viewer NCBICNNM2 [Mapview hg19]  
OMIM607803   613882   616418   
Gene and transcription
Genbank (Entrez)AF216962 AK000071 AK023066 AK023479 AK090785
RefSeq transcript (Entrez)NM_017649 NM_199076 NM_199077
Consensus coding sequences : CCDS (NCBI)CNNM2
Gene ExpressionCNNM2 [ NCBI-GEO ]   CNNM2 [ EBI - ARRAY_EXPRESS ]   CNNM2 [ SEEK ]   CNNM2 [ MEM ]
Gene Expression Viewer (FireBrowse)CNNM2 [ Firebrowse - Broad ]
GenevisibleExpression of CNNM2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54805
GTEX Portal (Tissue expression)CNNM2
Human Protein AtlasENSG00000148842-CNNM2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H8M5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H8M5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H8M5
PhosPhoSitePlusQ9H8M5
Domaine pattern : Prosite (Expaxy)CBS (PS51371)    CNNM (PS51846)   
Domains : Interpro (EBI)CBS_dom    CNNM   
Domain families : Pfam (Sanger)CBS (PF00571)    DUF21 (PF01595)   
Domain families : Pfam (NCBI)pfam00571    pfam01595   
Conserved Domain (NCBI)CNNM2
PDB (RSDB)4IY0    4IY2    4IY4    4IYS    6DJ3    6N7E   
PDB Europe4IY0    4IY2    4IY4    4IYS    6DJ3    6N7E   
PDB (PDBSum)4IY0    4IY2    4IY4    4IYS    6DJ3    6N7E   
PDB (IMB)4IY0    4IY2    4IY4    4IYS    6DJ3    6N7E   
Structural Biology KnowledgeBase4IY0    4IY2    4IY4    4IYS    6DJ3    6N7E   
SCOP (Structural Classification of Proteins)4IY0    4IY2    4IY4    4IYS    6DJ3    6N7E   
CATH (Classification of proteins structures)4IY0    4IY2    4IY4    4IYS    6DJ3    6N7E   
SuperfamilyQ9H8M5
AlphaFold pdb e-kbQ9H8M5   
Human Protein Atlas [tissue]ENSG00000148842-CNNM2 [tissue]
HPRD07418
Protein Interaction databases
DIP (DOE-UCLA)Q9H8M5
IntAct (EBI)Q9H8M5
BioGRIDCNNM2
STRING (EMBL)CNNM2
ZODIACCNNM2
Ontologies - Pathways
QuickGOQ9H8M5
Ontology : AmiGOATP binding  plasma membrane  transport  magnesium ion homeostasis  magnesium ion homeostasis  magnesium ion transmembrane transporter activity  integral component of membrane  basolateral plasma membrane  transmembrane transporter activity  intracellular membrane-bounded organelle  intracellular membrane-bounded organelle  magnesium ion transmembrane transport  
Ontology : EGO-EBIATP binding  plasma membrane  transport  magnesium ion homeostasis  magnesium ion homeostasis  magnesium ion transmembrane transporter activity  integral component of membrane  basolateral plasma membrane  transmembrane transporter activity  intracellular membrane-bounded organelle  intracellular membrane-bounded organelle  magnesium ion transmembrane transport  
NDEx NetworkCNNM2
Atlas of Cancer Signalling NetworkCNNM2
Wikipedia pathwaysCNNM2
Orthology - Evolution
OrthoDB54805
GeneTree (enSembl)ENSG00000148842
Phylogenetic Trees/Animal Genes : TreeFamCNNM2
Homologs : HomoloGeneCNNM2
Homology/Alignments : Family Browser (UCSC)CNNM2
Gene fusions - Rearrangements
Fusion : QuiverCNNM2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNNM2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNNM2
dbVarCNNM2
ClinVarCNNM2
MonarchCNNM2
1000_GenomesCNNM2 
Exome Variant ServerCNNM2
GNOMAD BrowserENSG00000148842
Varsome BrowserCNNM2
ACMGCNNM2 variants
VarityQ9H8M5
Genomic Variants (DGV)CNNM2 [DGVbeta]
DECIPHERCNNM2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCNNM2 
Mutations
ICGC Data PortalCNNM2 
TCGA Data PortalCNNM2 
Broad Tumor PortalCNNM2
OASIS PortalCNNM2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCNNM2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCNNM2
Mutations and Diseases : HGMDCNNM2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCNNM2
DgiDB (Drug Gene Interaction Database)CNNM2
DoCM (Curated mutations)CNNM2
CIViC (Clinical Interpretations of Variants in Cancer)CNNM2
Cancer3DCNNM2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607803    613882    616418   
Orphanet10345   
DisGeNETCNNM2
MedgenCNNM2
Genetic Testing Registry CNNM2
NextProtQ9H8M5 [Medical]
GENETestsCNNM2
Target ValidationCNNM2
Huge Navigator CNNM2 [HugePedia]
ClinGenCNNM2
Clinical trials, drugs, therapy
MyCancerGenomeCNNM2
Protein Interactions : CTDCNNM2
Pharm GKB GenePA26669
PharosQ9H8M5
Clinical trialCNNM2
Miscellaneous
canSAR (ICR)CNNM2
HarmonizomeCNNM2
DataMed IndexCNNM2
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCNNM2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:46:25 CEST 2021

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