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CNOT10 (CCR4-NOT transcription complex subunit 10)

Identity

Alias_namesCCR4-NOT transcription complex, subunit 10
Alias_symbol (synonym)FLJ12890
FLJ13165
Other alias-
HGNC (Hugo) CNOT10
LocusID (NCBI) 25904
Atlas_Id 61946
Location 3p22.3  [Link to chromosome band 3p22]
Location_base_pair Starts at 32685145 and ends at 32773875 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ACTN1 (14q24.1) / CNOT10 (3p22.3)HUNK (21q22.11) / CNOT10 (3p22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)CNOT10   23817
Cards
Entrez_Gene (NCBI)CNOT10  25904  CCR4-NOT transcription complex subunit 10
Aliases
GeneCards (Weizmann)CNOT10
Ensembl hg19 (Hinxton)ENSG00000182973 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000182973 [Gene_View]  chr3:32685145-32773875 [Contig_View]  CNOT10 [Vega]
ICGC DataPortalENSG00000182973
TCGA cBioPortalCNOT10
AceView (NCBI)CNOT10
Genatlas (Paris)CNOT10
WikiGenes25904
SOURCE (Princeton)CNOT10
Genetics Home Reference (NIH)CNOT10
Genomic and cartography
GoldenPath hg38 (UCSC)CNOT10  -     chr3:32685145-32773875 +  3p22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CNOT10  -     3p22.3   [Description]    (hg19-Feb_2009)
EnsemblCNOT10 - 3p22.3 [CytoView hg19]  CNOT10 - 3p22.3 [CytoView hg38]
Mapping of homologs : NCBICNOT10 [Mapview hg19]  CNOT10 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK021695 AK022576 AK022952 AK023227 AK027026
RefSeq transcript (Entrez)NM_001256741 NM_001256742 NM_015442
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)CNOT10
Cluster EST : UnigeneHs.444851 [ NCBI ]
CGAP (NCI)Hs.444851
Alternative Splicing GalleryENSG00000182973
Gene ExpressionCNOT10 [ NCBI-GEO ]   CNOT10 [ EBI - ARRAY_EXPRESS ]   CNOT10 [ SEEK ]   CNOT10 [ MEM ]
Gene Expression Viewer (FireBrowse)CNOT10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25904
GTEX Portal (Tissue expression)CNOT10
Human Protein AtlasENSG00000182973-CNOT10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H9A5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H9A5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H9A5
Splice isoforms : SwissVarQ9H9A5
PhosPhoSitePlusQ9H9A5
Domains : Interpro (EBI)TPR-like_helical_dom    TPR_repeat   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Domain families : Smart (EMBL)TPR (SM00028)  
Conserved Domain (NCBI)CNOT10
DMDM Disease mutations25904
Blocks (Seattle)CNOT10
SuperfamilyQ9H9A5
Human Protein Atlas [tissue]ENSG00000182973-CNOT10 [tissue]
Peptide AtlasQ9H9A5
HPRD16731
IPIIPI01014565   IPI00878368   IPI00396314   IPI00794753   IPI00791933   IPI01015949   IPI00790411   IPI00925558   IPI00926613   IPI00924836   
Protein Interaction databases
DIP (DOE-UCLA)Q9H9A5
IntAct (EBI)Q9H9A5
FunCoupENSG00000182973
BioGRIDCNOT10
STRING (EMBL)CNOT10
ZODIACCNOT10
Ontologies - Pathways
QuickGOQ9H9A5
Ontology : AmiGOnuclear-transcribed mRNA poly(A) tail shortening  protein binding  nucleus  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of translation  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  membrane  CCR4-NOT complex  gene silencing by RNA  
Ontology : EGO-EBInuclear-transcribed mRNA poly(A) tail shortening  protein binding  nucleus  cytosol  transcription, DNA-templated  regulation of transcription, DNA-templated  regulation of translation  DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest  membrane  CCR4-NOT complex  gene silencing by RNA  
Pathways : KEGGRNA degradation   
NDEx NetworkCNOT10
Atlas of Cancer Signalling NetworkCNOT10
Wikipedia pathwaysCNOT10
Orthology - Evolution
OrthoDB25904
GeneTree (enSembl)ENSG00000182973
Phylogenetic Trees/Animal Genes : TreeFamCNOT10
HOVERGENQ9H9A5
HOGENOMQ9H9A5
Homologs : HomoloGeneCNOT10
Homology/Alignments : Family Browser (UCSC)CNOT10
Gene fusions - Rearrangements
Tumor Fusion PortalCNOT10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNOT10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNOT10
dbVarCNOT10
ClinVarCNOT10
1000_GenomesCNOT10 
Exome Variant ServerCNOT10
ExAC (Exome Aggregation Consortium)ENSG00000182973
GNOMAD BrowserENSG00000182973
Genetic variants : HAPMAP25904
Genomic Variants (DGV)CNOT10 [DGVbeta]
DECIPHERCNOT10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCNOT10 
Mutations
ICGC Data PortalCNOT10 
TCGA Data PortalCNOT10 
Broad Tumor PortalCNOT10
OASIS PortalCNOT10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCNOT10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDCNOT10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch CNOT10
DgiDB (Drug Gene Interaction Database)CNOT10
DoCM (Curated mutations)CNOT10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)CNOT10 (select a term)
intoGenCNOT10
Cancer3DCNOT10(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETCNOT10
MedgenCNOT10
Genetic Testing Registry CNOT10
NextProtQ9H9A5 [Medical]
TSGene25904
GENETestsCNOT10
Target ValidationCNOT10
Huge Navigator CNOT10 [HugePedia]
snp3D : Map Gene to Disease25904
BioCentury BCIQCNOT10
ClinGenCNOT10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25904
Chemical/Pharm GKB GenePA134862503
Clinical trialCNOT10
Miscellaneous
canSAR (ICR)CNOT10 (select the gene name)
Probes
Litterature
PubMed30 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineCNOT10
EVEXCNOT10
GoPubMedCNOT10
iHOPCNOT10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:07:14 CET 2017

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