Identity
HGNC
LOCATION
12q15
LOCUSID
ALIAS
CDC36,HSPC131,IDNADFS,NOT2,NOT2H
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4848
MIM: 604909
HGNC: 7878
Ensembl: ENSG00000111596
Variants:
dbSNP: 4848
ClinVar: 4848
TCGA: ENSG00000111596
COSMIC: CNOT2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34018673 | 2021 | CNOT2 haploinsufficiency in a 40-year-old man with intellectual disability, autism, and seizures. | 2 |
| 34680125 | 2021 | Inhibition of CNOT2 Induces Apoptosis via MID1IP1 in Colorectal Cancer Cells by Activating p53. | 10 |
| 34018673 | 2021 | CNOT2 haploinsufficiency in a 40-year-old man with intellectual disability, autism, and seizures. | 2 |
| 34680125 | 2021 | Inhibition of CNOT2 Induces Apoptosis via MID1IP1 in Colorectal Cancer Cells by Activating p53. | 10 |
| 31894259 | 2020 | CCR4‑NOT transcription complex subunit 2 regulates TRAIL sensitivity in non‑small‑cell lung cancer cells via the STAT3 pathway. | 0 |
| 31894259 | 2020 | CCR4‑NOT transcription complex subunit 2 regulates TRAIL sensitivity in non‑small‑cell lung cancer cells via the STAT3 pathway. | 0 |
| 31155293 | 2019 | CNOT2 facilitates dengue virus infection via negatively modulating IFN-Independent Non-Canonical JAK/STAT pathway. | 5 |
| 31155293 | 2019 | CNOT2 facilitates dengue virus infection via negatively modulating IFN-Independent Non-Canonical JAK/STAT pathway. | 5 |
| 29024811 | 2018 | CNOT2 promotes proliferation and angiogenesis via VEGF signaling in MDA-MB-231 breast cancer cells. | 31 |
| 29024811 | 2018 | CNOT2 promotes proliferation and angiogenesis via VEGF signaling in MDA-MB-231 breast cancer cells. | 31 |
| 28615693 | 2017 | The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription. | 15 |
| 28615693 | 2017 | The CCR4-NOT complex contributes to repression of Major Histocompatibility Complex class II transcription. | 15 |
| 27273514 | 2016 | The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression. | 24 |
| 27273514 | 2016 | The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression. | 24 |
| 24121232 | 2013 | Structure and assembly of the NOT module of the human CCR4-NOT complex. | 72 |
Citation
Dessen P
CNOT2 (CCR4-NOT transcription complex subunit 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/40114/cnot2
