Atlas of Genetics and Cytogenetics in Oncology and Haematology


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CNTN2 (contactin 2)

Identity

Alias (NCBI)AXT
FAME5
TAG-1
TAX
TAX1
HGNC (Hugo) CNTN2
HGNC Alias symbTAG-1
TAX1
HGNC Previous nameTAX
 AXT
HGNC Previous namecontactin 2 (axonal)
LocusID (NCBI) 6900
Atlas_Id 40118
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 205043212 and ends at 205078289 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EDRF1 (10q26.13) / CNTN2 (1q32.1)MAT2A (2p11.2) / CNTN2 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)CNTN2   2172
Cards
Entrez_Gene (NCBI)CNTN2    contactin 2
AliasesAXT; FAME5; TAG-1; TAX; 
TAX1
GeneCards (Weizmann)CNTN2
Ensembl hg19 (Hinxton)ENSG00000184144 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184144 [Gene_View]  ENSG00000184144 [Sequence]  chr1:205043212-205078289 [Contig_View]  CNTN2 [Vega]
ICGC DataPortalENSG00000184144
TCGA cBioPortalCNTN2
AceView (NCBI)CNTN2
Genatlas (Paris)CNTN2
SOURCE (Princeton)CNTN2
Genetics Home Reference (NIH)CNTN2
Genomic and cartography
GoldenPath hg38 (UCSC)CNTN2  -     chr1:205043212-205078289 +  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)CNTN2  -     1q32.1   [Description]    (hg19-Feb_2009)
GoldenPathCNTN2 - 1q32.1 [CytoView hg19]  CNTN2 - 1q32.1 [CytoView hg38]
ImmunoBaseENSG00000184144
Genome Data Viewer NCBICNTN2 [Mapview hg19]  
OMIM190197   615400   
Gene and transcription
Genbank (Entrez)AB074271 AK095531 AK124736 AK289985 AK309108
RefSeq transcript (Entrez)NM_001346083 NM_005076
Consensus coding sequences : CCDS (NCBI)CNTN2
Gene ExpressionCNTN2 [ NCBI-GEO ]   CNTN2 [ EBI - ARRAY_EXPRESS ]   CNTN2 [ SEEK ]   CNTN2 [ MEM ]
Gene Expression Viewer (FireBrowse)CNTN2 [ Firebrowse - Broad ]
GenevisibleExpression of CNTN2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6900
GTEX Portal (Tissue expression)CNTN2
Human Protein AtlasENSG00000184144-CNTN2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02246   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02246  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02246
PhosPhoSitePlusQ02246
Domaine pattern : Prosite (Expaxy)FN3 (PS50853)    IG_LIKE (PS50835)   
Domains : Interpro (EBI)Basigin-like    Contactin-2    FN3_dom    FN3_sf    Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2   
Domain families : Pfam (Sanger)fn3 (PF00041)    I-set (PF07679)   
Domain families : Pfam (NCBI)pfam00041    pfam07679   
Domain families : Smart (EMBL)FN3 (SM00060)  IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)CNTN2
PDB (RSDB)2OM5   
PDB Europe2OM5   
PDB (PDBSum)2OM5   
PDB (IMB)2OM5   
Structural Biology KnowledgeBase2OM5   
SCOP (Structural Classification of Proteins)2OM5   
CATH (Classification of proteins structures)2OM5   
SuperfamilyQ02246
AlphaFold pdb e-kbQ02246   
Human Protein Atlas [tissue]ENSG00000184144-CNTN2 [tissue]
HPRD01826
Protein Interaction databases
DIP (DOE-UCLA)Q02246
IntAct (EBI)Q02246
BioGRIDCNTN2
STRING (EMBL)CNTN2
ZODIACCNTN2
Ontologies - Pathways
QuickGOQ02246
Ontology : AmiGOmicrotubule cytoskeleton organization  protein binding  plasma membrane  plasma membrane  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  axon guidance  axonal fasciculation  learning  adult walking behavior  cell surface  regulation of cell morphogenesis involved in differentiation  positive regulation of protein processing  cerebral cortex GABAergic interneuron migration  central nervous system myelination  carbohydrate binding  axon  regulation of axon diameter  receptor internalization  node of Ranvier  identical protein binding  neuronal cell body  myelin sheath  protein self-association  juxtaparanode region of axon  clustering of voltage-gated potassium channels  synapse  negative regulation of neuron differentiation  regulation of neuronal synaptic plasticity  regulation of astrocyte differentiation  positive regulation of adenosine receptor signaling pathway  dendrite self-avoidance  protein localization to juxtaparanode region of axon  establishment of protein localization to juxtaparanode region of axon  presynaptic membrane organization  cell-cell adhesion mediator activity  anchored component of postsynaptic membrane  anchored component of postsynaptic membrane  
Ontology : EGO-EBImicrotubule cytoskeleton organization  protein binding  plasma membrane  plasma membrane  cell adhesion  homophilic cell adhesion via plasma membrane adhesion molecules  axon guidance  axonal fasciculation  learning  adult walking behavior  cell surface  regulation of cell morphogenesis involved in differentiation  positive regulation of protein processing  cerebral cortex GABAergic interneuron migration  central nervous system myelination  carbohydrate binding  axon  regulation of axon diameter  receptor internalization  node of Ranvier  identical protein binding  neuronal cell body  myelin sheath  protein self-association  juxtaparanode region of axon  clustering of voltage-gated potassium channels  synapse  negative regulation of neuron differentiation  regulation of neuronal synaptic plasticity  regulation of astrocyte differentiation  positive regulation of adenosine receptor signaling pathway  dendrite self-avoidance  protein localization to juxtaparanode region of axon  establishment of protein localization to juxtaparanode region of axon  presynaptic membrane organization  cell-cell adhesion mediator activity  anchored component of postsynaptic membrane  anchored component of postsynaptic membrane  
Pathways : KEGGCell adhesion molecules (CAMs)   
NDEx NetworkCNTN2
Atlas of Cancer Signalling NetworkCNTN2
Wikipedia pathwaysCNTN2
Orthology - Evolution
OrthoDB6900
GeneTree (enSembl)ENSG00000184144
Phylogenetic Trees/Animal Genes : TreeFamCNTN2
Homologs : HomoloGeneCNTN2
Homology/Alignments : Family Browser (UCSC)CNTN2
Gene fusions - Rearrangements
Fusion : QuiverCNTN2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerCNTN2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)CNTN2
dbVarCNTN2
ClinVarCNTN2
MonarchCNTN2
1000_GenomesCNTN2 
Exome Variant ServerCNTN2
GNOMAD BrowserENSG00000184144
Varsome BrowserCNTN2
ACMGCNTN2 variants
VarityQ02246
Genomic Variants (DGV)CNTN2 [DGVbeta]
DECIPHERCNTN2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisCNTN2 
Mutations
ICGC Data PortalCNTN2 
TCGA Data PortalCNTN2 
Broad Tumor PortalCNTN2
OASIS PortalCNTN2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICCNTN2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DCNTN2
Mutations and Diseases : HGMDCNTN2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaCNTN2
DgiDB (Drug Gene Interaction Database)CNTN2
DoCM (Curated mutations)CNTN2
CIViC (Clinical Interpretations of Variants in Cancer)CNTN2
Cancer3DCNTN2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM190197    615400   
Orphanet11734   
DisGeNETCNTN2
MedgenCNTN2
Genetic Testing Registry CNTN2
NextProtQ02246 [Medical]
GENETestsCNTN2
Target ValidationCNTN2
Huge Navigator CNTN2 [HugePedia]
ClinGenCNTN2
Clinical trials, drugs, therapy
MyCancerGenomeCNTN2
Protein Interactions : CTDCNTN2
Pharm GKB GenePA26686
PharosQ02246
Clinical trialCNTN2
Miscellaneous
canSAR (ICR)CNTN2
HarmonizomeCNTN2
DataMed IndexCNTN2
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXCNTN2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Mon Oct 4 15:04:37 CEST 2021

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